scholarly journals Clinicopathological Diagnosis of Gliomatosis Cerebri

10.5772/22244 ◽  
2011 ◽  
Author(s):  
Jiro Akimoto
Keyword(s):  
Gliomatosis Cerebri

Gliomatosis cerebri que simula encefalitis

2008 ◽  
Vol 47 (05) ◽  
pp. 271
Author(s):  
Mario Martínez Galdámez ◽  
Ana Piazza Dobarganes ◽  
Gertrudis Saucedo Díaz ◽  
Beatriz Brea Álvarez ◽  
Eduardo Fandiño Benito ◽  
...  
Keyword(s):  
Gliomatosis Cerebri

Neuroradiology case of the day. Gliomatosis cerebri.

1995 ◽  
Vol 165 (1) ◽  
pp. 214-214
Author(s):  
D S Enterline ◽  
N C Davey ◽  
R D Tien
Keyword(s):  
Gliomatosis Cerebri

Epilepsia partialis continua associated with widespread gliomatosis cerebri

2002 ◽  
Vol 27 (5) ◽  
pp. 392-396 ◽  
Author(s):  
Eli Shahar ◽  
Uri Kramer ◽  
Dvora Nass ◽  
David Savitzki
Keyword(s):  
Gliomatosis Cerebri ◽  
Epilepsia Partialis Continua

Gliomatosis cerebri: Results with radiation therapy

Cancer ◽  
1996 ◽  
Vol 78 (8) ◽  
pp. 1789-1793 ◽  
Author(s):  
Scott C. Cozad ◽  
Patrick Townsend ◽  
Robert A. Morantz ◽  
Arthur B. Jenny ◽  
John J. Kepes ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Gliomatosis Cerebri

Gliomatosis cerebri mimicking Rasmussen encephalitis

2007 ◽  
Vol 107 (2) ◽  
pp. 143-146 ◽  
Author(s):  
Samer Ghostine ◽  
Ravi Raghavan ◽  
David Michelson ◽  
Barbara Holshouser ◽  
Karen Tong
Keyword(s):  
Gliomatosis Cerebri ◽  
Rasmussen Encephalitis

Gliomatosis Cerebri: A Review of 296 Cases from the ANOCEF Database and the Literature

2005 ◽  
Vol 76 (2) ◽  
pp. 201-205 ◽  
Author(s):  
Sophie Taillibert ◽  
Catherine Chodkiewicz ◽  
Florence Laigle-Donadey ◽  
Massimo Napolitano ◽  
Stéphanie Cartalat-Carel ◽  
...  
Keyword(s):  
Gliomatosis Cerebri

scholarly journals Patterns of presentation and failure in patients with gliomatosis cerebri treated with partial-brain radiation therapy

Cancer ◽  
2014 ◽  
Vol 120 (17) ◽  
pp. 2713-2720 ◽  
Author(s):  
Shravan Kandula ◽  
Amit M. Saindane ◽  
Roshan S. Prabhu ◽  
Sheela Hanasoge ◽  
Kirtesh R. Patel ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Gliomatosis Cerebri ◽  
Brain Radiation

Gliomatosis Cerebri in Six Dogs

2003 ◽  
Vol 40 (1) ◽  
pp. 97-102 ◽  
Author(s):  
B. Porter ◽  
A. DeLahunta ◽  
B. Summers
Keyword(s):  
Cranial Nerve ◽  
Gliomatosis Cerebri ◽  
Clinical Findings ◽  
Human Medicine ◽  
Glial Fibrillary Acid Protein ◽  
Neoplastic Cells ◽  
Diffuse Infiltration ◽  
Acid Protein ◽  
Pathologic Features ◽  
The Brain

Gliomatosis cerebri is a well-recognized entity in human medicine characterized by unusually widespread infiltration of the neuraxis by neoplastic glial cells with relative preservation of brain architecture. This report describes the pathologic features of the disease in six dogs. The dogs ranged from 3 to 9 years of age (mean 6.1 years) without evidence of breed predilection; five of the six dogs were neutered or intact males. The clinical findings were mixed (including depression, circling, cranial nerve deficits), reflecting the diffuse nature of the disease. Histologically, there was remarkably diffuse infiltration of the white and gray matter of the brain by small numbers of elongated neoplastic cells. Areas of greater cellularity formed grossly visible lesions in four cases. Anisocytosis and pleomorphism were greater in areas of higher cellularity. Other features of tumor growth included subpial accumulation, neuronal satellitosis, perivascular cuffing, and tropism for cranial nerve and brain stem nuclei. Neoplastic cells were negative on immunohistochemical stains for glial fibrillary acid protein (GFAP) and leukocyte markers, reflecting the uncertain histogenesis of these unusual neoplasms.

NCOG-34. A DESCRIPTIVE ANALYSIS OF GLIOMATOSIS CEREBRI CASES, COMPARED ACCORDING TO IDH STATUS

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi159-vi159
Author(s):  
Lisa Boris ◽  
Elizabeth Vera ◽  
Alvina Acquaye ◽  
Nicole Briceno ◽  
Anna Choi ◽  
...  
Keyword(s):  
Descriptive Analysis ◽  
Symptom Burden ◽  
Gliomatosis Cerebri ◽  
Molecular Characteristics ◽  
Study Cohort ◽  
Depression And Anxiety ◽  
Natural History Study ◽  
Adjuvant Temozolomide ◽  
Patient Reported ◽  
Grade Ii

Abstract Gliomatosis cerebri (GC) is a controversial entity no longer recognized as a histopathologic-defined diagnosis, characterized by diffuse, commonly bilateral infiltration of cerebral hemispheres. The purpose of this report is to describe clinical, imaging, patient-reported outcomes (PRO’s) and pathologic characteristics of clinically-defined cases from a large natural history study cohort (N=769). Of 19 patients, 10 male, 16 white, mean age at diagnosis 43 (19-70), seventeen presented as primary GC, while 2 developed GC after treatment. Ten patients were IDH-WT, 7 IDH-M, and 2 IDH undetermined. The majority (7/10) IDH-WT patients presented acutely (5 with seizures), whereas, 3 had a protracted presentation of 2 weeks-3months with 6/10 having enhancing tumors and 8/10 undergoing biopsy only. On histopathologic review, 4 were anaplastic astrocytoma (AA), 3 GBMs, 2 grade II astrocytoma, and 1 histone-mutated glioma. Nearly all (9/10) IDH-WT patients received radiation with concurrent and adjuvant temozolomide. 7/10 IDH-WT patients had a survival of only 1.5yrs or less from diagnosis. Of the 7 IDH-M patients, 4 had protracted presentations of 1 month-5 years. 6/7 had non-enhancing tumors at presentation. 4 had biopsy only and 3 underwent partial resection. 3 were AA, 2 grade II astrocytoma, 1 grade II oligodendroglioma, and 1 grade IV astrocytoma. 3/7 received radiation with concurrent and adjuvant temozolomide, 3/7 chemotherapy alone, and 1 RT alone. All 7 IDH-M patients survived 3+ years from diagnosis (range 3-10+ yrs). Both patients who developed GC later, were IDH-M, with prolonged survival (3.5yrs and the other still alive 10+yrs). PRO's at time of last clinical assessment revealed GC patients to be highly symptomatic with mean overall symptom burden, depression, and anxiety higher than our overall glioma population. GC patients have a varied clinical course mandating further investigation to enable better prognostic definition to refine treatments based on the varying clinical and molecular characteristics.

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