scholarly journals Type 1 Diabetes Mellitus: Redefining the Future of Cardiovascular Complications with Novel Treatments

10.5772/22092 ◽  
2011 ◽  
Author(s):  
Anwar B. ◽  
Nadine S. ◽  
Sawsan M. Al Lafi ◽  
Shushan B. ◽  
Suzan S.
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Cardiovascular Complications ◽  
Novel Treatments ◽  
The Future

Cardiovascular complications in type 1 diabetes mellitus

2010 ◽  
Vol 36 (5) ◽  
pp. 341-344 ◽  
Author(s):  
M.-C. Brindisi ◽  
B. Bouillet ◽  
B. Vergès ◽  
S. Halimi
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Cardiovascular Complications

scholarly journals Formation of risk groups based on the QT interval and the corrected QT interval in children with type 1 diabetes

2021 ◽  
pp. 15-21
Author(s):  
V.G. Maidannik ◽  
◽  
I.O. Mituriayeva ◽  
G.V. Gnyloskurenko ◽  
Y.M. Kryvonos ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Insulin Therapy ◽  
Type 1 Diabetes Mellitus ◽  
Qt Interval ◽  
Risk Groups ◽  
Cardiovascular Complications ◽  
Qtc Interval ◽  
Long Qt

The course of type 1 diabetes in children can be complicated by cardiovascular disorders in the form of life-threatening arrhythmias, especially in patients with congenital long QT syndrome (LQTS). It remains relevant to determine the risk groups for developing such complications, to search for convenient diagnostic algorithms and subsequent management tactics for children with type 1 diabetes mellitus (T1DM) who have acquired and congenital long LQTS. Study purpose is to determine the risk groups for the development of cardiovascular complications of type 1 diabetes mellitus in children, by the QT and corrected (QTc) interval ranges. Materials and methods. The examination involved 53 children with type 1 diabetes, who were divided into 2 groups depending on the duration of the disease. To determine the parameters relevant for the study, the bioelectrical activity of the heart was assessed by ECG and Holter ECG monitoring. For additional assessment of the patients' condition over a long period of time, they were offered to keep a diary with monitoring of parameters important for the study. Statistical processing of the research results was carried out with the SPSS 22.0 program. Results and conclusions. Changes in the duration of the QTc interval and its variance have been proved depending on the duration of the disease and influence of the glycemia level plus insulin therapy on the value of these indicators. For children with newly diagnosed type 1 diabetes, an algorithm has been developed to identify risk groups for the development of cardiovascular complications associated with LQTS, which makes it possible to determine three risk groups and the tactics of their further management. According to the authors, the main goal of reducing the risk of developing cardiovascular complications in the form of ventricular arrhythmias (which can lead to sudden death syndrome) is the timely diagnosis of long QT interval syndrome. Recognition of congenital LQTS is important, since unstable glycemic levels and the appointment of insulin therapy can significantly worsen the child's condition. For children with newly diagnosed type 1 diabetes mellitus before the appointment of insulin therapy, the authors propose their own algorithm for identifying risk groups for the development of cardiovascular complications associated with long QT interval syndrome and tactics for their further management. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of these Institutes. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: type 1 diabetes, long QT syndrome, patient management algorithm.

Novel Treatments in Type 1 Diabetes Mellitus

2017 ◽  
pp. 14-14
Author(s):  
Paresh Dandona ◽  
Ajay Chaudhuri ◽  
Nitesh Kuhadiya ◽  
Husam Ghanim
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Novel Treatments

scholarly journals Early prediction of cardiovascular disease in patients with type 1 diabetes

2021 ◽  
Vol 30 (2) ◽  
pp. 17-21
Author(s):  
A.E. Petrosyan ◽  
M.L. Diane ◽  
E.O. Kotova
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Arterial Stiffness ◽  
Type 1 Diabetes Mellitus ◽  
Cardiovascular Complications ◽  
Early Prediction ◽  
Early Prevention ◽  
Vascular Bed

The authors review approaches to the early prediction of cardiovascular diseases in patients with type 1 diabetes mellitus, e.g. using central arterial pressure, arterial stiffness, and a loss of arterial stiffness gradient. The bulk of data was presented either on diabetes mellitus in general or on type 2 diabetes mellitus, while there is a clear gap in information on type 1 diabetes mellitus. The study of the elastic properties of the vascular bed in these patients can become the basis for the early prevention of cardiovascular complications.

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