scholarly journals Roles and Mechanisms of Estrogen and Estrogen Receptors in Breast Cancer Resistant to Chemotherapy

10.5772/21786 ◽  
2011 ◽  
Author(s):  
Weimin Fan ◽  
Meihua Sui
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptors

Phytoestrogens and Mitochondrial Biogenesis in Breast Cancer. Influence of Estrogen Receptors Ratio

2014 ◽  
Vol 20 (35) ◽  
pp. 5594-5618 ◽  
Author(s):  
Pilar Roca ◽  
Jorge Sastre-Serra ◽  
Mercedes Nadal-Serrano ◽  
Daniel Pons ◽  
Ma Blanquer-Rossello ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptors ◽  
Mitochondrial Biogenesis

Nuclear and cytoplasmic estrogen receptors and progesterone receptors in breast cancer

1980 ◽  
Vol 16 (8) ◽  
pp. 1027-1033 ◽  
Author(s):  
R. Hähnel ◽  
R.K. Partridge ◽  
L. Gavet ◽  
E. Twaddle ◽  
T. Ratajczak
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptors ◽  
Progesterone Receptors

scholarly journals Curcumin inhibits leptin gene expression and secretion in breast cancer cells by estrogen receptors

2014 ◽  
Vol 14 (1) ◽  
pp. 66 ◽  
Author(s):  
Kazem Nejati-Koshki ◽  
Abolfazl Akbarzadeh ◽  
Mohammad Pourhassan-Moghaddam
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Estrogen Receptors ◽  
Cancer Cells ◽  
Breast Cancer Cells

Contribution of Estrogen Receptors to the Strategy of Breast Cancer Treatment

1981 ◽  
pp. 267-285 ◽  
Author(s):  
J. C. Heuson ◽  
R. Paridaens ◽  
E. Ferrazzi ◽  
N. Legros ◽  
G. Leclercq ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Estrogen Receptors ◽  
Breast Cancer Treatment

scholarly journals Symbiotic Gene Activation is Interrupted by Endocrine Disrupting Chemicals

2001 ◽  
Vol 1 ◽  
pp. 653-655 ◽  
Author(s):  
Jennifer E. Fox ◽  
Matthew E. Burow ◽  
John A. McLachlan
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Estrogen Receptors ◽  
Mammalian Cell Culture ◽  
Endocrine Disrupting Chemicals ◽  
Gene Activation ◽  
Symbiotic Gene ◽  
Endocrine Disrupting ◽  
Plant Chemicals ◽  
By Products

Endocrine disrupting chemicals (EDCs) include organochlorine pesticides, plastics manufacturing by-products, and certain herbicides[1]. These chemicals have been shown to disrupt hormonal signaling in exposed wildlife, lab animals, and mammalian cell culture by binding to estrogen receptors (ER-α and ER-β) and affecting the expression of estrogen responsive genes[2,3]. Additionally, certain plant chemicals, termed phytoestrogens, are also able to bind to estrogen receptors and modulate gene expression, and as such also may be considered EDCs[4]. One example of phytoestrogen action is genistein, a phytochemical produced by soybeans, binding estrogen receptors, and changing expression of estrogen responsive genes which certain studies have linked to a lower incidence of hormonally related cancers in Japanese populations[5]. Why would plants make compounds that are able to act as estrogens in the human body? Obviously, soybeans do not intentionally produce phytoestrogens to prevent breast cancer in Japanese women.

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