scholarly journals Poly (L-glutamic acid)-Paclitaxel Conjugates for Cancer Treatment

10.5772/21474 ◽  
2012 ◽  
Author(s):  
Shuang-Qing Zhang
Keyword(s):  
Glutamic Acid ◽  
Cancer Treatment

Nano-rods of doxorubicin with poly(l-glutamic acid) as a carrier-free formulation for intratumoral cancer treatment

2016 ◽  
Vol 4 (45) ◽  
pp. 7283-7292 ◽  
Author(s):  
Saina Yang ◽  
Feiyan Zhu ◽  
Qian Wang ◽  
Fuxin Liang ◽  
Xiaozhong Qu ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Cancer Treatment ◽  
Survival Time ◽  
Release Profile ◽  
Intratumoral Administration ◽  
Tumor Bearing ◽  
Carrier Free ◽  
Nano Rods

Nano-rods of doxorubicin (DOX) were prepared by co-assembly with poly(l-glutamic acid) (PGA) and demonstrated a desired release profile for intratumoral administration that significantly prolonged the survival time of tumor-bearing mice.

scholarly journals Tumor microenvironment-targeted poly-L-glutamic acid-based combination conjugate for enhanced triple negative breast cancer treatment

Biomaterials ◽  
2018 ◽  
Vol 186 ◽  
pp. 8-21 ◽  
Author(s):  
Juan J. Arroyo-Crespo ◽  
Ana Armiñán ◽  
David Charbonnier ◽  
Leandro Balzano-Nogueira ◽  
Francisco Huertas-López ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Microenvironment ◽  
Glutamic Acid ◽  
Cancer Treatment ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Breast Cancer Treatment

1077: A Novel Apoptosis-Inducing Gene and its Application in Prostate Cancer Treatment

2004 ◽  
Vol 171 (4S) ◽  
pp. 284-284
Author(s):  
Yi Lu ◽  
Jun Zhang ◽  
Ben Beheshti ◽  
Ximing J. Yang ◽  
Syamal K. Bhattacharya ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Treatment ◽  
Prostate Cancer Treatment

Molecular Mechanism of Apoptosis Induction by Resveratrol, a Natural Cancer Chemopreventive Agent

2008 ◽  
Vol 78 (1) ◽  
pp. 3-8 ◽  
Author(s):  
Fan ◽  
Jiang ◽  
Zhang ◽  
Bai
Keyword(s):  
Cancer Treatment ◽  
Molecular Mechanism ◽  
Apoptosis Induction ◽  
Protective Agents ◽  
Chemopreventive Agent ◽  
Naturally Occurring ◽  
Apoptosis Pathways ◽  
Present Understanding

In efforts to identify naturally occurring compounds that act as protective agents, resveratrol, a phytoalexin existing in wine, has attracted much interest because of its diverse pharmacological characteristics. Considering that apoptosis induction is the most potent defense approach for cancer treatment, we have tried to summarize our present understanding of apoptosis induction by resveratrol based on the two major apoptosis pathways.

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