scholarly journals Intramuscular IL-12 Electrogene Therapy for Treatment of Spontaneous Canine Tumors

Author(s):  
Maja Cemazar ◽  
Gregor Sersa ◽  
Darja Pavlin ◽  
Natasa Tozo
Keyword(s):  
Immunobiology ◽  
2020 ◽  
Vol 225 (2) ◽  
pp. 151892 ◽  
Author(s):  
P. Cruz ◽  
E. Sosoniuk-Roche ◽  
I. Maldonado ◽  
C.G. Torres ◽  
A. Ferreira

Radiology ◽  
1978 ◽  
Vol 129 (1) ◽  
pp. 221-223 ◽  
Author(s):  
Tom R. Miller ◽  
Barry A. Siegel ◽  
William R. Fair ◽  
E. Kaye Smith ◽  
Michael J. Welch
Keyword(s):  

1994 ◽  
Vol 28 (4) ◽  
pp. 921-933 ◽  
Author(s):  
J.Mark Cline ◽  
Donald E Thrall ◽  
Gary L Rosner ◽  
James A Raleigh
Keyword(s):  

2020 ◽  
Author(s):  
Xiaobo Du ◽  
Bin Zhang ◽  
Fan Hu ◽  
Chuantao Xie ◽  
Haiyan Tian ◽  
...  

AbstractRegulating the immune system through tumor immunotherapy to defeat tumors is currently one of the most popular methods of tumor treatment. We previously found that the combinations of IL12, IL2 and GMCSF has superior antitumor activities. In this study, IL12IL2GMCSF fusion protein was produced from 293 cells transduced by expression lentiviral vector. IL12IL2GMCSF fusion protein was injected into canine tumors, and the efficacy was monitored to evaluate the potential of tumor immunotherapy. In 14 canines injected with IL12IL2GMCSF protein, 6 had a complete response (CR), 7 had a partial response (PR), and 1 had stable disease (SD). IL12IL2GMCSF fusion protein has great anti-tumor potential. Intratumoral injection of IL12IL2GMCSF can effectively treat tumors without severe adverse effects. It provides a promising immune therapeutics in canine cancers.


2011 ◽  
Vol 11 (1A) ◽  
pp. S42-S43
Author(s):  
A.E. Hansen ◽  
A.T. Kristensen ◽  
I. Law ◽  
J.T. Jorgensen ◽  
F.J. McEvoy ◽  
...  
Keyword(s):  

2013 ◽  
Vol 40 (6Part28) ◽  
pp. 477-477
Author(s):  
T Bradshaw ◽  
S Bowen ◽  
N Jallow ◽  
L Forrest ◽  
R Jeraj
Keyword(s):  

2020 ◽  
Vol 132 ◽  
pp. 466-473
Author(s):  
Yuki Hamamura ◽  
Takayuki Nakagawa ◽  
Masaru Okuda ◽  
Shunsuke Noguchi ◽  
Masaya Igase ◽  
...  

1995 ◽  
Vol 34 (3) ◽  
pp. 345-349 ◽  
Author(s):  
James A. Raleigh ◽  
Elaine M. Zeman ◽  
Dennise P. Calkins ◽  
Margaret C. McEntee ◽  
Donald E. Thrall
Keyword(s):  

2006 ◽  
Vol 182 (9) ◽  
pp. 518-524 ◽  
Author(s):  
Carla Rohrer Bley ◽  
Stefanie Ohlerth ◽  
Malgorzata Roos ◽  
Melanie Wergin ◽  
Roger Achermann ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document