scholarly journals Immunoglobulin G4-related inflammatory aortic aneurysm

Author(s):  
Hidetoshi Okabe ◽  
Mitsuaki Ishi
2019 ◽  
Vol 108 (3) ◽  
pp. e179-e181
Author(s):  
Robert Blazekovic ◽  
Mislav Planinc ◽  
Jasmina Catic ◽  
Davor Baric ◽  
Daniel Unic ◽  
...  

2012 ◽  
Vol 26 (1) ◽  
pp. 108.e1-108.e4 ◽  
Author(s):  
Magdiel Trinidad-Hernandez ◽  
Audra A. Duncan

2018 ◽  
Vol 47 (1) ◽  
pp. 31-35
Author(s):  
Osamu Tominaga ◽  
Tatsuhiko Komiya ◽  
Hiroshi Tsuneyoshi ◽  
Takeshi Shimamoto ◽  
Toshifumi Hiraoka ◽  
...  

Heart ◽  
2021 ◽  
pp. heartjnl-2020-318041
Author(s):  
Aamina Shakir ◽  
Yurong Wheeler ◽  
Guha Krishnaswamy

Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory disease characterised by multiorgan lymphoplasmacytic infiltration, obliterative phlebitis and storiform fibrosis. It can be associated with cardiovascular pathology. The objective of this narrative review is to summarise the published literature on cardiovascular manifestations of IgG4-RD and to provide a basis for diagnosis and management of the condition by the practising cardiologist.We propose the following categorisations of cardiovascular IgG4-RD: aortitis, medium-vessel arteritis, pulmonary vascular disease, phlebitis, valvulopathy, pericarditis, myocardial disease and antineutrophilic cytoplasmic antibody-associated vasculitis. We also review herein developments in radiological diagnosis and reported medical and surgical therapies. Cardiovascular lesions frequently require procedural and/or surgical interventions, such as aortic aneurysm repair and valve replacement. IgG4-RD of the cardiovascular system results in serious complications that can be missed if not evaluated aggressively. These are likely underdiagnosed, as clinical presentations frequently mimic cardiovascular disease due to more common aetiologies (myocardial infarction, abdominal aortic aneurysm and so on). While systemic corticosteroids are the mainstay of IgG4-RD treatment, biological and disease-modifying agents are becoming more widely used. Cardiologists should be aware of cardiovascular IgG4-RD as a differential diagnosis, and understand the roles of corticosteroids, disease-modifying agents and biologicals, as well as their integration with surgical approaches. There are several knowledge gaps, including diagnosis, risk factors, pathogenesis and appropriate management in Ig4-RD of the cardiovascular system. Areas lacking well-conducted randomized trials include safety of steroids in the setting of vascular aneurysms and the role of disease-modifying drugs and biological agents in patients with established cardiovascular complications of this multifaceted enigmatic disease.


2020 ◽  
Vol 70 (10) ◽  
pp. 812-819
Author(s):  
Satomi Kasashima ◽  
Atsuhiro Kawashima ◽  
Fuminori Kasashima ◽  
Yasushi Matsumoto ◽  
Satoru Ozaki

2017 ◽  
Vol 26 (3) ◽  
pp. 231-233
Author(s):  
Szabolcs Miskolczi ◽  
Mary N Sheppard ◽  
Gábor Bogáts ◽  
Laszlo Göbölös

Thoracic aortic aneurysm is an indication for major cardiovascular operative procedures. The etiology is usually hypertension and/or atherosclerotic disease; reaching a certain diameter often results in acute aortic syndrome. Immunoglobulin G4-related aortitis, characterized by lymphoplasmacytic vascular tunica media induration without well-defined underlying infectious or autoimmune systemic causes, is uncommon. Histological similarity to immunoglobulin G4 disease in other organs suggests that this aortitis might be a manifestation of systemic pathology. We describe a case of double-locus lymphoplasmacytic aortitis in a 72-year-old man who had the incidental finding of intramural hematoma on elective thoracic computed tomography as part of a respiratory work-up.


2008 ◽  
Vol 39 (6) ◽  
pp. 975-980 ◽  
Author(s):  
Yasushi Matsumoto ◽  
Satomi Kasashima ◽  
Atsuhiro Kawashima ◽  
Hisao Sasaki ◽  
Masamitsu Endo ◽  
...  

2003 ◽  
Vol 38 (3) ◽  
pp. 492-497 ◽  
Author(s):  
E.S Haug ◽  
J.F Skomsvoll ◽  
G Jacobsen ◽  
T.B Halvorsen ◽  
O.D Sæther ◽  
...  

2007 ◽  
Vol 203 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Noriyuki Sakata ◽  
Kazuki Nabeshima ◽  
Hiroshi Iwasaki ◽  
Tadashi Tashiro ◽  
Noriko Uesugi ◽  
...  

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