scholarly journals Effect on Workers’ Health Owing to Pesticides Exposure: Endocrine Target

10.5772/18203 ◽  
2011 ◽  
Author(s):  
Lidia Caporossi ◽  
Bruno Papaleo
Keyword(s):  
Pesticides Exposure

Glutathione S-transferase M1 null genotype, household pesticides exposure and cutaneous melanoma

2016 ◽  
Vol 26 (6) ◽  
pp. 625-630 ◽  
Author(s):  
Cristina Fortes ◽  
Simona Mastroeni ◽  
Giordano Bottà ◽  
Paolo Boffetta ◽  
Gianluca Antonelli ◽  
...  
Keyword(s):  
Cutaneous Melanoma ◽  
Glutathione S Transferase ◽  
Pesticides Exposure ◽  
Household Pesticides

Pesticides Exposure and Dopaminergic Neurodegeneration

2021 ◽  
Author(s):  
Jingsong Xiao ◽  
Xunhu Dong ◽  
Xi Zhang ◽  
Feng Ye ◽  
Jin Cheng ◽  
...  
Keyword(s):  
Dopaminergic Neurodegeneration ◽  
Pesticides Exposure

scholarly journals Exposure to low doses of pesticides induces an immune response and the production of nitric oxide in honeybees

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Merle T. Bartling ◽  
Susanne Thümecke ◽  
José Herrera Russert ◽  
Andreas Vilcinskas ◽  
Kwang-Zin Lee
Keyword(s):  
Nitric Oxide ◽  
Immune Responses ◽  
Bacterial Pathogen ◽  
Wild Plants ◽  
P450 Monooxygenase ◽  
Abiotic Stressors ◽  
Genes Encoding ◽  
Pesticides Exposure ◽  
Colony Survival ◽  
Oxide Synthase

AbstractHoneybees are essential pollinators of many agricultural crops and wild plants. However, the number of managed bee colonies has declined in some regions of the world over the last few decades, probably caused by a combination of factors including parasites, pathogens and pesticides. Exposure to these diverse biotic and abiotic stressors is likely to trigger immune responses and stress pathways that affect the health of individual honeybees and hence their contribution to colony survival. We therefore investigated the effects of an orally administered bacterial pathogen (Pseudomonas entomophila) and low-dose xenobiotic pesticides on honeybee survival and intestinal immune responses. We observed stressor-dependent effects on the mean lifespan, along with the induction of genes encoding the antimicrobial peptide abaecin and the detoxification factor cytochrome P450 monooxygenase CYP9E2. The pesticides also triggered the immediate induction of a nitric oxide synthase gene followed by the delayed upregulation of catalase, which was not observed in response to the pathogen. Honeybees therefore appear to produce nitric oxide as a specific defense response when exposed to xenobiotic stimuli. The immunity-related and stress-response genes we tested may provide useful stressor-dependent markers for ecotoxicological assessment in honeybee colonies.

scholarly journals Airborne occupational exposures and the risk of developing respiratory symptoms and airway obstruction in the Lifelines Cohort Study

Thorax ◽  
2021 ◽  
pp. thoraxjnl-2020-216721
Author(s):  
Md Omar Faruque ◽  
H Marike Boezen ◽  
Hans Kromhout ◽  
Roel Vermeulen ◽  
Ute Bültmann ◽  
...  
Keyword(s):  
Cohort Study ◽  
Airway Obstruction ◽  
Chronic Bronchitis ◽  
Chronic Cough ◽  
Respiratory Symptoms ◽  
Occupational Exposures ◽  
Control Measures ◽  
High Exposure ◽  
Pesticides Exposure

ObjectivesTo date, only a few studies have investigated the associations between occupational exposures and respiratory outcomes longitudinally in the general population. We investigated the associations between occupational exposures and the development of respiratory symptoms and airway obstruction in the Lifelines Cohort Study.MethodsWe included 35 739 occupationally active subjects with data on chronic cough, chronic phlegm, chronic bronchitis or airway obstruction at baseline and approximately 4.5 years follow-up. Exposures to biological dust, mineral dust, gases/fumes, pesticides, solvents and metals in the current job at baseline were estimated with the ALOHA+job-exposure matrix (JEM). Airway obstruction was defined as FEV1/FVC below the lower limit of normal. Logistic regression analysis adjusted for baseline covariates was used to investigate the associations.ResultsAt follow-up, 1888 (6.0%), 1495 (4.7%), 710 (2.5%) and 508 (4.5%) subjects had developed chronic cough, chronic phlegm, chronic bronchitis and airway obstruction, respectively. High exposure to biological dust was associated with a higher odds to develop chronic cough and chronic bronchitis. High exposure to pesticides was associated with a higher odds for the development of all respiratory symptoms and airway obstruction. In the multiple exposures analyses, only the association between pesticides exposure and respiratory symptoms remained.ConclusionsSubjects exposed to high pesticides had a higher odds to develop respiratory symptoms on average 4.5 years later. Control measures should be taken to reduce pesticides exposure among the working population to prevent respiratory symptoms and airway obstruction.

scholarly journals Which Factors Influence Farmers’ Use of Protective Measures During Pesticides Exposure?

2019 ◽  
Vol 67 (7) ◽  
pp. 338-349
Author(s):  
Maryam Afshari ◽  
Jalal Poorolajal ◽  
Forouzan Rezapur-Shahkolai ◽  
Mohammad Javad Assari ◽  
Akram Karimi-Shahanjarini
Keyword(s):  
Positive Impact ◽  
Contextual Factors ◽  
Physiological Arousal ◽  
Protective Behaviors ◽  
Protective Measures ◽  
Safety Measures ◽  
Factors Affecting ◽  
Face To Face ◽  
Pesticides Exposure ◽  
Positive Effect

Farmers in developing countries use harmful pesticides while taking few or no protective measures. There is limited evidence on factors affecting their safety measures. The objective of this study was to identify the underlying factors influencing farmers’ protective behaviors (PBs) and use of personal protective equipment (PPE) during the exposure to pesticides. From April to August 2017, a descriptive study was conducted in Twiserkan County in western Iran among 474 farmers from 104 villages. A questionnaire was developed to measure demographic characteristics and factors suggested in integrated agent-centered (IAC) framework. The questionnaire was validated in terms of content validity through expert reviews and tested for reliability in a group of farmers. Data were collected by face-to-face interviews with farmers. Physiological arousal (β = .154, p < .05), intention (β = .345, p < .05), habit (β = .188, p < .05), and contextual factors (β = .101, p < .05) had a significant and positive impact on farmers engaging in pesticide PBs. Among the assessed factors, only physiological arousal (β = .122, p < .05) and habit (β = .646, p < .05) were found to have a significant and positive effect on the use of PPE, but the intention (β = –.039, p > .05) and contextual factors (β = –.009, p > .05) had no significant relation with the use of PPE. The results of this study identified determinants of farmers’ safety measures. Our results suggest that the IAC framework could serve as a guide to developing a more effective intervention for safety measures of Iranian farmers.

scholarly journals Bioconcentration of glyphosate in wetland biofilms

2020 ◽  
Author(s):  
Laura Beecraft ◽  
Rebecca Rooney
Keyword(s):  
Trophic Levels ◽  
Breakdown Product ◽  
Exposure Risk ◽  
Surrounding Water ◽  
Wetland Water ◽  
Pesticides Exposure ◽  
Wetland Water Quality ◽  
Herbicide Glyphosate

AbstractWetland biofilms were exposed to the herbicide glyphosate via in situ field exposures and controlled microcosm experiments to measure bioconcentration and metabolism of glyphosate by biofilm organisms. Glyphosate concentrations in biofilms were orders of magnitude higher than the surrounding water, bioconcentration factors averaged 835 and 199 in field- and lab-exposed biofilms, respectively. Glyphosate in water where it had been detected in biofilms at field-exposed sites ranged from below detection (<0.001 ppm) up to 0.13 ppm. Glyphosate bioconcentration in biofilms was inversely proportional to levels in the surrounding water, and the retention kinetics were similar to both adsorption and enzymatic models. Microorganisms present in both the water and biofilms metabolized glyphosate to its primary breakdown product aminomethyl phosphonic acid (AMPA), with increased rates of breakdown in and around the biofilms. Photosynthetic efficiency of the algae within the biofilms was not affected by 24 h glyphosate controlled exposures. Our results demonstrate the role of biofilms in improving wetland water quality by removing contaminants like glyphosate, but also as a potential exposure route to higher trophic levels via consumption. Due to bioconcentration of pesticides, exposure risk to organisms consuming or living in biofilms may be much higher than indicated by concentrations in ambient water samples.

scholarly journals The level of residue of pesticides in vegetables by GC-MS, health risk and the negligence in implementation of policies, India

2020 ◽  
Vol 8 (1) ◽  
pp. 407
Author(s):  
Azra Khan ◽  
J. P. Srivastava ◽  
Dipak Kumar Bose
Keyword(s):  
Health Risk ◽  
Small Scale ◽  
Daily Consumption ◽  
Pesticides Residues ◽  
Maximum Residue Level ◽  
Residual Level ◽  
Pesticides Exposure ◽  
Vegetable Farming ◽  
Small Scale Farmers ◽  
Anxiety Depression

Background: Over the past years there has been an increase in the use of pesticides in vegetable farming developing countries. This study describes over spraying pesticide use among small-scale farmers in Jasra block of Allahabad district of Uttar Pradesh.Methods: The purpose of this study was proposed to determine the pesticide residual level in 120 vegetable samples like brinjal, lady finger, tomato, chili, cabbage analysed by (GC-MS) gas chromatography mass spectrophotometry technique. Assessing the health risk due to the daily consumption of contaminated vegetables Jasra block of Allahabad district.Results: Samples were contaminated with organophosphorus group namely chlorpyriphos in bringal 1.215 mg/kg, and less carbamate (carbaryl) from 0.025 mg/kg, ladyfinger with the concentration of  chlorpyriphos 0.418 mg/kg carbaryl 0.092 with very less residue of dichlorvos 0.005, green chilli with the concentration of chloropyriphos 1.507 mg/kg. Carbaryl 0.033 mg/kg, tomato with the concentration of chlorpyriphos 1.631mg/kg followed by less carbaryl 0.026 mg/kg, malathione, 1.890 mg/kg followed by cabbage with the concentration of chlorphyriphos 1.907 mg/kg. And less carbaryl concentration was recorded 0.064 mg/kg.Conclusions: Five vegetable with pesticides residues, exceeding the maximum residue level (MRL) recommended by FSSAI, FAO/WHO. Farmers over spraying methods leads to acute diseases like respiratory tract infection, extreme weakness, and longer use  pesticides exposure leads to chronic diseases like asthma, anxiety, depression, cancer, leukemia, allergies, nausea, vomiting, headache, blur vision, skin itching etc.to minimize the risk of diseases policy making and farmer protection standard and proper handling techniques, trained professionals to improve health safety.

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