scholarly journals Creating Scalable and Addressable Biomimetic Membrane Arrays in Biomedicine

10.5772/14000 ◽  
2011 ◽  
Author(s):  
Jesper Sndergaard ◽  
Claus Helix
Keyword(s):  
Biomimetic Membrane

scholarly journals Development of FGF-2-loaded electrospun waterborne polyurethane fibrous membranes for bone regeneration

2020 ◽  
Author(s):  
Chi Zhang ◽  
Jianxiong Wang ◽  
Yujie Xie ◽  
Li Wang ◽  
Lishi Yang ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Periodontal Regeneration ◽  
Waterborne Polyurethane ◽  
Related Factors ◽  
Positive Meaning ◽  
Chain Extenders ◽  
Biomimetic Membrane ◽  
Fibrous Membranes ◽  
Green Chemical Synthesis ◽  
Gbr Membrane

Abstract Guided bone regeneration (GBR) membrane has been used to improve functional outcomes for periodontal regeneration. However, few studies have focused on the biomimetic membrane mimicking the vascularization of the periodontal membrane. This study aimed to fabricate waterborne polyurethane (WPU) fibrous membranes loaded fibroblast growth factor-2 (FGF-2) via emulsion electrospinning, which can promote regeneration of periodontal tissue via the vascularization of the biomimetic GBR membrane. A biodegradable WPU was synthesized by using lysine and dimethylpropionic acid as chain extenders according to the rule of green chemical synthesis technology. The WPU fibers with FGF-2 was fabricated via emulsion electrospinning. The results confirmed that controlled properties of the fibrous membrane had been achieved with controlled degradation, suitable mechanical properties and sustained release of the factor. The immunohistochemical expression of angiogenic-related factors was positive, meaning that FGF-2 loaded in fibers can significantly promote cell vascularization. The fiber scaffold loaded FGF-2 has the potential to be used as a functional GBR membrane to promote the formation of extraosseous blood vessels during periodontal repairing.

scholarly journals Doxycycline-Doped Polymeric Membranes Induced Growth, Differentiation and Expression of Antigenic Phenotype Markers of Osteoblasts

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1063
Author(s):  
Manuel Toledano-Osorio ◽  
Francisco J. Manzano-Moreno ◽  
Manuel Toledano ◽  
Antonio L. Medina-Castillo ◽  
Victor J. Costela-Ruiz ◽  
...  
Keyword(s):  
Composite Membranes ◽  
Polymeric Membranes ◽  
Potential Candidate ◽  
Polymeric Scaffold ◽  
Hla Dr ◽  
Proliferation And Differentiation ◽  
Physical Barriers ◽  
Antigenic Phenotype ◽  
Biomimetic Membrane ◽  
Phenotype Markers

Polymeric membranes are employed in guided bone regeneration (GBR) as physical barriers to facilitate bone in-growth. A bioactive and biomimetic membrane with the ability to participate in the healing and regeneration of the bone is necessary. The aim of the present study was to analyze how novel silicon dioxide composite membranes functionalized with zinc or doxycycline can modulate the osteoblasts’ proliferation, differentiation, and expression of selected antigenic markers related to immunomodulation. Nanostructured acrylate-based membranes were developed, blended with silica, and functionalized with zinc or doxycycline. They were subjected to MG63 osteoblast-like cells culturing. Proliferation was assessed by MTT-assay, differentiation by evaluating the alkaline phosphatase activity by a spectrophotometric method and antigenic phenotype was assessed by flow cytometry for selected markers. Mean comparisons were conducted by one-way ANOVA and Tukey tests (p < 0.05). The blending of silica nanoparticles in the tested non-resorbable polymeric scaffold improved the proliferation and differentiation of osteoblasts, but doxycycline doped scaffolds attained the best results. Osteoblasts cultured on doxycycline functionalized membranes presented higher expression of CD54, CD80, CD86, and HLA-DR, indicating a beneficial immunomodulation activity. Doxycycline doped membranes may be a potential candidate for use in GBR procedures in several challenging pathologies, including periodontal disease.

Assessment of the impact of nanoparticles on the activity of biomimetic membrane

2021 ◽  
Vol XXXVII (1) ◽  
pp. 89-100
Author(s):  
Dorota Kondej
Keyword(s):  
Occupational Safety ◽  
Biological Membranes ◽  
Structure And Function ◽  
Lipid Monolayer ◽  
Biomimetic Membranes ◽  
Safety And Health ◽  
Biomimetic Membrane ◽  
And Function ◽  
The Impact

This paper presents basic information on a structure and function of biological membranes. Types of biomimetic membranes modelling properties of biological membranes were introduced. The method of testing surface properties of a lipid monolayer, which is the basic type of biomimetic membranes, was described. The presented method makes it possible to evaluate the effect of nanoparticles on the surface activity of biomimetic membranes based on the determination of the surface index MA. This article discusses the problems of occupational safety and health, which are covered by health sciences and environmental engineering.

A facile synthesis of bifunctional phospholipids for biomimetic membrane engineering

Tetrahedron ◽  
2004 ◽  
Vol 60 (51) ◽  
pp. 11765-11770 ◽  
Author(s):  
Xue-Long Sun ◽  
Wanxing Cui ◽  
Toshistugu Kai ◽  
Elliot L. Chaikof
Keyword(s):  
Facile Synthesis ◽  
Biomimetic Membrane ◽  
Membrane Engineering

Biomimetic Membrane Simulation for Water Desalination

2018 ◽  
Author(s):  
Peter Ozaveshe Oviroh ◽  
Rokhsareh Akbarzadeh ◽  
Tien-Chien Jen
Keyword(s):  
Water Purification ◽  
Saline Water ◽  
New Technology ◽  
Pure Water ◽  
Water Desalination ◽  
Membrane Thickness ◽  
Nanoporous Membranes ◽  
Factors Affecting ◽  
Biomimetic Membrane ◽  
Low Efficiency

Reverse Osmosis (RO) for the desalination of saline water is associated with tremendous energy costs and low efficiency. Improvements in nanotechnology have led to the development of a variety of nanoporous membranes for water purification. Biomimetic membrane is an emerging new technology for water purification. Consequently, there is still much to study about the function and structure of these kinds of membranes. The purpose of this work was to determine which factors influence membrane performance. The focus was on those factors affecting membranes in pure water. Biomimetic membrane using MoS2 which has a higher rate of ion rejection and higher water permeability was studied through molecular dynamics simulations using reactive force fields (ReaxFF). The behaviour of the membrane before subjecting it to desalination was studied. The effect of water temperature, atmospheric pressure and membrane thickness on performance of membrane was studied. The permeability flux was calculated and compared in different conditions and the relation between these factors was revealed.

scholarly journals 3P208 Effects of lipid oxidation products on domain formation of biomimetic membrane(13A. Biological & Artifical membrane: Structure & Property,Poster)

2013 ◽  
Vol 53 (supplement1-2) ◽  
pp. S246
Author(s):  
Tsuyoshi Yoda ◽  
Wataru Inui ◽  
Huong Thi Than Phan ◽  
Naofumi Shimokawa ◽  
Mun'delanji C. Vestergaard ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Membrane Structure ◽  
Oxidation Products ◽  
Domain Formation ◽  
Structure Property ◽  
Lipid Oxidation Products ◽  
Biomimetic Membrane
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