scholarly journals Effects of Achyranthes Bidentata Polysaccharide on Growth Performance, Immunological, Adrenal, and Somatotropic Responses of Weaned Pigs Challenged with Escherichia coli Lipopolysaccharide

2008 ◽  
Vol 21 (8) ◽  
pp. 1189-1195 ◽  
Author(s):  
Guanglun Guo ◽  
Yulan Liu ◽  
Wei Fan ◽  
Jie Han ◽  
Yongqing Hou ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Growth Performance ◽  
Weaned Pigs ◽  
Achyranthes Bidentata ◽  
Escherichia Coli Lipopolysaccharide

Effects of dietary β-glucan supplementation on growth performance and immunological and metabolic parameters of weaned pigs administered with Escherichia coli lipopolysaccharide

2018 ◽  
Vol 9 (6) ◽  
pp. 3338-3343 ◽  
Author(s):  
Cheng Wu ◽  
Qin Xu ◽  
Ru Wang ◽  
Linlin Qin ◽  
Xie Peng ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Growth Performance ◽  
Blood Parameters ◽  
Metabolic Parameters ◽  
Weaned Pigs ◽  
Escherichia Coli Lipopolysaccharide

The objective of this study was to determine the effects of dietary β-glucan (BG) supplementation on growth performance and blood parameters in weaned pigs administered with Escherichia coli lipopolysaccharide (LPS).

Fructooligosaccharides improve growth performance and intestinal epithelium function in weaned pigs exposed to enterotoxigenic Escherichia coli

2020 ◽  
Vol 11 (11) ◽  
pp. 9599-9612
Author(s):  
Lei Liu ◽  
Daiwen Chen ◽  
Bing Yu ◽  
Heng Yin ◽  
Zhiqing Huang ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Growth Performance ◽  
Intestinal Epithelium ◽  
Intestinal Injury ◽  
Enterotoxigenic Escherichia Coli ◽  
Weaned Pigs ◽  
Protective Potential

This study was conducted to explore the protective potential of fructooligosaccharides (FOS) against enterotoxigenic Escherichia coli (ETEC)-induced inflammation and intestinal injury in weaned pigs.

scholarly journals Growth performance and gut health of Escherichia coli-challenged weaned pigs fed diets supplemented with a Bacillus subtilis direct-fed microbial

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Sangwoo Park ◽  
Jung Wook Lee ◽  
Kevin Jerez Bogota ◽  
David Francis ◽  
Jolie Caroline González-Vega ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Bacillus Subtilis ◽  
Growth Performance ◽  
Feed Efficiency ◽  
Basal Diet ◽  
Feed Additives ◽  
Growth Promoter ◽  
Gut Health ◽  
Weaned Pigs ◽  
E Coli

Abstract This study was conducted to investigate the effects of a direct-fed microbial (DFM) product (Bacillus subtilis strain DSM 32540) in weaned pigs challenged with K88 strain of Escherichia coli on growth performance and indicators of gut health. A total of 21 weaned pigs [initial body weight (BW) = 8.19 kg] were housed individually in pens and fed three diets (seven replicates per diet) for 21 d in a completely randomized design. The three diets were a corn-soybean meal-based basal diet without feed additives, a basal diet with 0.25% antibiotics (neo-Oxy 10-10; neomycin + oxytetracycline), or a basal diet with 0.05% DFM. All pigs were orally challenged with a subclinical dose (6.7 × 108 CFU/mL) of K88 strain of E. coli on day 3 of the study (3 d after weaning). Feed intake and BW data were collected on days 0, 3, 7, 14, and 21. Fecal scores were recorded daily. On day 21, pigs were sacrificed to determine various indicators of gut health. Supplementation of the basal diet with antibiotics or DFM did not affect the overall (days 0–21) growth performance of pigs. However, antibiotics or DFM supplementation increased (P = 0.010) gain:feed (G:F) of pigs during the post-E. coli challenge period (days 3–21) by 23% and 24%, respectively. The G:F for the DFM-supplemented diet did not differ from that for the antibiotics-supplemented diet. The frequency of diarrhea for pigs fed a diet with antibiotics or DFM tended to be lower (P = 0.071) than that of pigs fed the basal diet. The jejunal villous height (VH) and the VH to crypt depth ratio (VH:CD) were increased (P < 0.001) by 33% and 35%, respectively, due to the inclusion of antibiotics in the basal diet and by 43% and 41%, respectively due to the inclusion of DFM in the basal diet. The VH and VH:CD for the DFM-supplemented diet were greater (P < 0.05) than those for the antibiotics-supplemented diet. Ileal VH was increased (P < 0.05) by 46% due to the inclusion of DFM in the basal diet. The empty weight of small intestine, cecum, or colon relative to live BW was unaffected by dietary antibiotics or DFM supplementation. In conclusion, the addition of DFM to the basal diet improved the feed efficiency of E. coli-challenged weaned pigs to a value similar to that of the antibiotics-supplemented diet and increased jejunal VH and VH:CD ratio to values greater than those for the antibiotics-supplemented diet. Thus, under E. coli challenge, the test DFM product may replace the use of antibiotics as a growth promoter in diets for weaned pigs to improve feed efficiency and gut integrity.

226 Soluble fiber improved growth performance of weaned pigs challenged with enterotoxigenic Escherichia coli

2017 ◽  
Vol 95 (suppl_2) ◽  
pp. 108-109
Author(s):  
Q. Li ◽  
C. L. Loving ◽  
N. K. Gabler ◽  
E. R. Burrough ◽  
J. F. Patience
Keyword(s):  
Escherichia Coli ◽  
Growth Performance ◽  
Enterotoxigenic Escherichia Coli ◽  
Soluble Fiber ◽  
Weaned Pigs

scholarly journals Fructooligosaccharides improves growth performance and intestinal epithelium function in weaned pigs exposure to Enterotoxigenic  Escherichia coli

2020 ◽  
Author(s):  
Lei Liu ◽  
daiwen Chen ◽  
Bing Yu ◽  
Yin Heng ◽  
Zhiqing Huang ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Amino Acid ◽  
Growth Performance ◽  
Intestinal Epithelium ◽  
Amino Acid Transporter ◽  
Enterotoxigenic Escherichia Coli ◽  
Villus Height ◽  
Weaned Pigs ◽  
Glucose Transporter 2 ◽  
Acid Transporter

Abstract Background This study was conducted to explore the protective potential of Fructooligosaccharides (FOS) against Enterotoxigenic Escherichia coli (ETEC)-induced inflammation and intestinal injury in weaned pigs. Methods Twenty-four weaned pigs were randomly assigned into three groups: (1) non-challenge (CON), (2) ETEC-challenge (ECON), and (3) ETEC challenge + 250 mg/kg FOS (EFOS). On day 19, non-challenged pigs were orally infused with sterilized culture while pigs in other groups were orally infused with ETEC (2.5 × 1010 colony-forming units). After 3 days, pigs were slaughtered for sample collection. Results We show that ETEC-challenged significantly reduced average daily gain (ADG); however, FOS improved the ADG (P < 0.05) and apparent digestibility of crude protein (CP), gross energy (GE), and ash in the ETEC-challenged pigs (P < 0.05). FOS reduced plasma concentrations of IL-1β and TNF-α, and elevated the concentrations of immunoglobulin A (IgA) and immunoglobulin M (IgM) (P < 0.05). Interestingly, FOS elevated villus height in duodenum, and elevated the ratio of villus height to crypt depth in the duodenum and ileum in the ETEC-challenged pigs (P < 0.05). Moreover, FOS increased lactase activity in the duodenum and ileum (P < 0.05). The activities of sucrase and alkaline phosphatase (AKP) were higher in EFOS group than in the ECON group (P < 0.05). Importantly, FOS up-regulated the expressions of critical genes in intestinal epithelium function such as zonula occludens-1 (ZO-1), L-type amino acid transporter-1 (LAT1), and cationic amino acid transporter-1 (CAT1) in the duodenum and the expressions of ZO-1 and glucose transporter-2 (GLUT2) in the jejunum (P < 0.05). FOS also up-regulated the expressions of occludin, fatty acid transporter-4 (FATP4), sodium glucose transport protein 1 (SGLT1), and GLUT2 in the ileum (P < 0.05). FOS significantly increased the concentrations of acetic acid, propionic acid and butyric acid in the cecal digesta. Additionally, FOS reduced the populations of Escherichia coli, but elevated the populations of Bacillus and Bifidobacterium in the caecal digesta (P < 0.05). Conclusions These results suggested that FOS can improve the growth performance and intestinal health in weaned pigs upon ETEC challenge, which was associated with suppressed inflammatory responses and improved intestinal epithelium functions and microbiota.

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