scholarly journals Protein sparing effect and amino acid utilization in broilers fed two types of lysine

1995 ◽  
Vol 8 (4) ◽  
pp. 403-409 ◽  
Author(s):  
K. N. Heo ◽  
I. K. Han ◽  
H. Lee
Keyword(s):  
Amino Acid ◽  
Protein Sparing ◽  
Amino Acid Utilization ◽  
Sparing Effect

scholarly journals METABOLIC CONNECTION BETWEEN PROLINE AND GLYCINE IN THE AMINO ACID UTILIZATION OF TORULOPSIS UTILIS

1947 ◽  
Vol 169 (3) ◽  
pp. 759-760
Author(s):  
G. Ehrensvärd ◽  
E. Sperber ◽  
E. Saluste ◽  
L. Reio ◽  
R. Stjernholm
Keyword(s):  
Amino Acid ◽  
Amino Acid Utilization

scholarly journals Dietary Protein Quality in Humans—An Overview

2005 ◽  
Vol 88 (3) ◽  
pp. 874-876 ◽  
Author(s):  
Paul J Moughan
Keyword(s):  
Amino Acid ◽  
Nutritive Value ◽  
Protein Quality ◽  
Current Method ◽  
Protein Digestibility ◽  
Food Protein ◽  
Amino Acid Utilization ◽  
Dietary Amino Acid ◽  
Amino Acid Requirements ◽  
Amino Acid Score

Abstract The first objective in evaluating protein quality is to permit a ranking of proteins according to their potential nutritive value and to permit detection of changes in nutritive value due to processing and/or storage. The second objective is to permit prediction of the contribution a food protein, or mixture of food proteins, makes toward meeting nitrogen and amino acid requirements for growth or maintenance. Different approaches are used in meeting these distinct aims. The preferred current method to meet the second aim is the protein digestibility corrected amino acid score (PDCAAS). This article introduces the concept of PDCAAS and places it in the context of the series of papers published in this Special Guest Editor Section addressing aspects of dietary amino acid utilization.

Involvement of D-Amino-Acid Oxidase in D-Amino Acid Utilization in the Mouse

1984 ◽  
Vol 114 (9) ◽  
pp. 1617-1621 ◽  
Author(s):  
Ryuichi Konno ◽  
Yosihiro Yasumura
Keyword(s):  
Amino Acid ◽  
Acid Oxidase ◽  
Amino Acid Oxidase ◽  
Amino Acid Utilization

scholarly journals The Paralogous Transcription Factors Stp1 and Stp2 of Candida albicans Have Distinct Functions in Nutrient Acquisition and Host Interaction

2020 ◽  
Vol 88 (5) ◽  
Author(s):  
Pedro Miramón ◽  
Andrew W. Pountain ◽  
Ambro van Hoof ◽  
Michael C. Lorenz
Keyword(s):  
Candida Albicans ◽  
Transcription Factors ◽  
Amino Acid ◽  
Cell Damage ◽  
Nutrient Acquisition ◽  
Acid Uptake ◽  
Content Type ◽  
Host Interaction ◽  
Amino Acid Utilization

ABSTRACT Nutrient acquisition is a central challenge for all organisms. For the fungal pathogen Candida albicans, utilization of amino acids has been shown to be critical for survival, immune evasion, and escape, while the importance of catabolism of host-derived proteins and peptides in vivo is less well understood. Stp1 and Stp2 are paralogous transcription factors (TFs) regulated by the Ssy1-Ptr3-Ssy5 (SPS) amino acid sensing system and have been proposed to have distinct, if uncertain, roles in protein and amino acid utilization. We show here that Stp1 is required for proper utilization of peptides but has no effect on amino acid catabolism. In contrast, Stp2 is critical for utilization of both carbon sources. Commensurate with this observation, we found that Stp1 controls a very limited set of genes, while Stp2 has a much more extensive regulon that is partly dependent on the Ssy1 amino acid sensor (amino acid uptake and catabolism) and partly Ssy1 independent (genes associated with filamentous growth, including the regulators UME6 and SFL2). The ssy1Δ/Δ and stp2Δ/Δ mutants showed reduced fitness in a gastrointestinal (GI) colonization model, yet induced greater damage to epithelial cells and macrophages in a manner that was highly dependent on the growth status of the fungal cells. Surprisingly, the stp1Δ/Δ mutant was better able to colonize the gut but the mutation had no effect on host cell damage. Thus, proper protein and amino acid utilization are both required for normal host interaction and are controlled by an interrelated network that includes Stp1 and Stp2.

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