scholarly journals Effects of dietary supplementation of lipid-coated zinc oxide on intestinal mucosal morphology and expression of the genes associated with growth and immune function in weanling pigs

2018 ◽  
Vol 31 (3) ◽  
pp. 403-409 ◽  
Author(s):  
Young Min Song ◽  
Myeong Hyeon Kim ◽  
Ha Na Kim ◽  
Insurk Jang ◽  
Jeong Hee Han ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Immune Function ◽  
Dietary Supplementation ◽  
Weanling Pigs ◽  
Mucosal Morphology

Effects of the lipid-coated zinc oxide dietary supplement on intestinal mucosal morphology and gene expression associated with the gut health in weanling pigs challenged with enterotoxigenic Escherichia coli K88

2018 ◽  
Vol 98 (3) ◽  
pp. 538-547 ◽  
Author(s):  
Jeong Hee Han ◽  
Min Hye Song ◽  
Ha Na Kim ◽  
Insurk Jang ◽  
C. Young Lee ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Zinc Oxide ◽  
Mrna Level ◽  
Enterotoxigenic Escherichia Coli ◽  
Mrna Levels ◽  
Gut Health ◽  
Weanling Pigs ◽  
Epithelial Barrier Function ◽  
Colony Forming Units ◽  
Mucosal Morphology

Effects of a lipid-coated zinc oxide (ZnO) Shield Zn® (SZ) vs. ZnO were evaluated. Forty 25-d-old weanling pigs were fed a nursery diet supplemented with 100 mg kg−1 Zn with ZnO (ZnO-100), ZnO-2500, SZ-100, -200, or -400. All piglets were challenged orally with 5 × 108 colony-forming units of enterotoxigenic Escherichia coli K88 on day 7 and euthanized on day 14. The fecal consistency score (FCS) was less for the SZ group vs. ZnO-100 (P < 0.05). The intestinal villus height:crypt depth ratio and goblet cell density were greater for the SZ group vs. ZnO-100. By regression analyses, SZ-100 to -200 and SZ-300 to -400 were comparable to ZnO-2500 in the FCS and intestinal variables, respectively. The jejunal mucosal mRNA level did not differ between the SZ group and either ZnO group in insulin-like growth factor-I and multiple structural proteins and cytokines including zonula occludens protein (ZO) 1 and interleukin (IL) 10 except for lower ZO-1 and IL-10 mRNA levels for the SZ group than for ZnO-2500 and ZnO-100, respectively. The ZO-1 mRNA level regressed positively on the supplemental SZ concentration. Results suggest that SZ play a role in epithelial barrier function and inflammation by modulating the expression of ZO-1 and IL-10.

scholarly journals Effects of dietary supplementation of bacteriophage with or without zinc oxide on the performance and gut development of weanling pigs

2016 ◽  
Vol 15 (3) ◽  
pp. 412-418 ◽  
Author(s):  
Suhyup Lee ◽  
Abdolreza Hosseindoust ◽  
Akshat Goel ◽  
Yohan Choi ◽  
Ill Kyong Kwon ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Dietary Supplementation ◽  
Gut Development ◽  
Weanling Pigs

scholarly journals Dietary Supplementation with Zinc Oxide Increases IGF-I and IGF-I Receptor Gene Expression in the Small Intestine of Weanling Piglets1

2006 ◽  
Vol 136 (7) ◽  
pp. 1786-1791 ◽  
Author(s):  
Xilong Li ◽  
Jingdong Yin ◽  
Defa Li ◽  
Xingjie Chen ◽  
Jianjun Zang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Zinc Oxide ◽  
Small Intestine ◽  
Receptor Gene ◽  
Dietary Supplementation ◽  
Igf I ◽  
Receptor Gene Expression

Effects of a Quillaja saponaria extract on growth performance and immune function of weanling pigs challenged with Salmonella typhimurium1

2002 ◽  
Vol 80 (7) ◽  
pp. 1939-1946 ◽  
Author(s):  
J. L. Turner ◽  
S. S. Dritz ◽  
J. J. Higgins ◽  
K. L. Herkelman ◽  
J. E. Minton
Keyword(s):  
Immune Function ◽  
Growth Performance ◽  
Weanling Pigs ◽  
Quillaja Saponaria
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