scholarly journals Genome–wide association study of carcass weight in commercial Hanwoo cattle

2018 ◽  
Vol 31 (3) ◽  
pp. 327-334 ◽  
Author(s):  
Zewdu Edea ◽  
Yeong Ho Jeoung ◽  
Sung-Sub Shin ◽  
Jaeul Ku ◽  
Sungbo Seo ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Carcass Weight ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Hanwoo Cattle

scholarly journals Haplotype-Based Genome-Wide Association Study and Identification of Candidate Genes Associated with Carcass Traits in Hanwoo Cattle

Genes ◽  
2020 ◽  
Vol 11 (5) ◽  
pp. 551
Author(s):  
Swati Srivastava ◽  
Krishnamoorthy Srikanth ◽  
Sohyoung Won ◽  
Ju-Hwan Son ◽  
Jong-Eun Park ◽  
...  
Keyword(s):  
Association Study ◽  
Candidate Genes ◽  
Haplotype Block ◽  
Genome Wide Association Study ◽  
Carcass Traits ◽  
Gene Set Enrichment Analysis ◽  
Genome Wide Association ◽  
Haplotype Blocks ◽  
Genome Wide ◽  
Hanwoo Cattle

Hanwoo, is the most popular native beef cattle in South Korea. Due to its extensive popularity, research is ongoing to enhance its carcass quality and marbling traits. In this study we conducted a haplotype-based genome-wide association study (GWAS) by constructing haplotype blocks by three methods: number of single nucleotide polymorphisms (SNPs) in a haplotype block (nsnp), length of genomic region in kb (Len) and linkage disequilibrium (LD). Significant haplotype blocks and genes associated with them were identified for carcass traits such as BFT (back fat thickness), EMA (eye Muscle area), CWT (carcass weight) and MS (marbling score). Gene-set enrichment analysis and functional annotation of genes in the significantly-associated loci revealed candidate genes, including PLCB1 and PLCB4 present on BTA13, coding for phospholipases, which might be important candidates for increasing fat deposition due to their role in lipid metabolism and adipogenesis. CEL (carboxyl ester lipase), a bile-salt activated lipase, responsible for lipid catabolic process was also identified within the significantly-associated haplotype block on BTA11. The results were validated in a different Hanwoo population. The genes and pathways identified in this study may serve as good candidates for improving carcass traits in Hanwoo cattle.

scholarly journals Genome-Wide Association Study Identifies Major Loci for Carcass Weight on BTA14 in Hanwoo (Korean Cattle)

PLoS ONE ◽  
2013 ◽  
Vol 8 (10) ◽  
pp. e74677 ◽  
Author(s):  
Seung Hwan Lee ◽  
Bong Hwan Choi ◽  
Dajeong Lim ◽  
Cedric Gondro ◽  
Young Min Cho ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Carcass Weight ◽  
Genome Wide Association ◽  
Korean Cattle ◽  
Genome Wide

scholarly journals Genome-wide association study identified three major QTL for carcass weight including the PLAG1-CHCHD7 QTN for stature in Japanese Black cattle

BMC Genetics ◽  
2012 ◽  
Vol 13 (1) ◽  
pp. 40 ◽  
Author(s):  
Shota Nishimura ◽  
Toshio Watanabe ◽  
Kazunori Mizoshita ◽  
Ken Tatsuda ◽  
Tatsuo Fujita ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Carcass Weight ◽  
Genome Wide Association ◽  
Japanese Black Cattle ◽  
Genome Wide ◽  
Major Qtl

Genome wide association study on memory in schizophrenia patients and unaffected probands

2009 ◽  
Vol 42 (05) ◽  
Author(s):  
B Konte ◽  
I Giegling ◽  
AM Hartmann ◽  
H Konnerth ◽  
P Muglia ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Genome Wide
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