scholarly journals Reconstruction of Secondary Type Congenital Hallux Varus with Modification of the Farmer Technique for Cover of Skin Defect: Report of Three Cases

2019 ◽  
Vol 13 (3) ◽  
pp. 72-76
Author(s):  
Sulaiman AR ◽  
Munajat I ◽  
M-Yusuf H ◽  
Nik-Jaffar NMS ◽  
Zarullail NH ◽  
...  
1998 ◽  
Vol 11 (01) ◽  
pp. 19-22 ◽  
Author(s):  
A. Steiner ◽  
Gaby Hirsbrunner

SummaryA newborn calf was admitted for evaluation of a primarily closed comminuted metaphyseal fracture of metacarpus III/IV. Closed reduction and application of transfixation pins and a fibreglass cast were performed. Ten days after pin removal, radiographs revealed that the initially healed fracture had collapsed, and osteomyelitis was diagnosed. Bacteriological culture from the deep draining tract yielded Actinomyces pyogenes and Staphylococcus aureus. Standard treatment of delayed union or nonunion caused by septic osteomyelitis consists of surgical debridement, rigid fixation, and long-time administration of antibiotics. In this case, we used surgical debridement, administration of a new long-acting local antibiotic (gentamicin- impregnated collagen sponges), and minimal external stabilization. At day 27 after initiation of this treatment, the skin defect had healed, and the fracture was stable on manual palpation.Standard treatment of delayed union or nonunion caused by septic osteomyelitis consists of surgical debridement, rigid fixation and prolonged administration of antibiotics. In the case described, we used surgical debridement, administration of a long-acting local antibiotic (gentamicin-impregnated collagen sponges), and minimal external stabilization. The promising outcome of this case and the good results in human surgery warrant further investigation in the use of gentamicin-impregnated collagen sponges in veterinary orthopaedics.


2021 ◽  
Vol 8 (1) ◽  
pp. 102-104
Author(s):  
Martin Aman ◽  
Arne Boecker ◽  
Ulrich Kneser ◽  
Leila Harhaus
Keyword(s):  

2014 ◽  
Vol 936 ◽  
pp. 1168-1172 ◽  
Author(s):  
Zhong Ping Chen ◽  
Chao Jian Xiang ◽  
Hua Qing Li

The oxide skin defect during hot rolling process for Cu-Ni-Si alloy strip was investigated. Oxide skin defects were analyzed by means of alloy elements detection and microstructures characterization. The characterization and test results showed that high temperature oxidation and silicon segregation are the main causes of the oxide skin defect. Pilot scale tests indicated that hot processing temperature for C70250 alloy should be lower than 950°C. Reducing atmosphere is recommended during the thermal treatment of Cu-Ni-Si alloys.


2013 ◽  
Vol 369 (22) ◽  
pp. 2137-2137
Author(s):  
Katie Ryan ◽  
Paul Moroney
Keyword(s):  

Biomolecules ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 834
Author(s):  
Ekaterina Blinova ◽  
Dmitry Pakhomov ◽  
Denis Shimanovsky ◽  
Marina Kilmyashkina ◽  
Yan Mazov ◽  
...  

Background: The main goal of our study was to explore the wound-healing property of a novel cerium-containing N-acethyl-6-aminohexanoate acid compound and determine key molecular targets of the compound mode of action in diabetic animals. Methods: Cerium N-acetyl-6-aminohexanoate (laboratory name LHT-8-17) as a 10 mg/mL aquatic spray was used as wound experimental topical therapy. LHT-8-17 toxicity was assessed in human skin epidermal cell culture using (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. A linear wound was reproduced in 18 outbred white rats with streptozotocin-induced (60 mg/kg i.p.) diabetes; planar cutaneous defect was modelled in 60 C57Bl6 mice with streptozotocin-induced (200 mg/kg i.p.) diabetes and 90 diabetic db/db mice. Firmness of the forming scar was assessed mechanically. Skin defect covering was histologically evaluated on days 5, 10, 15, and 20. Tissue TNF-α, IL-1β and IL-10 levels were determined by quantitative ELISA. Oxidative stress activity was detected by Fe-induced chemiluminescence. Ki-67 expression and CD34 cell positivity were assessed using immunohistochemistry. FGFR3 gene expression was detected by real-time PCR. LHT-8-17 anti-microbial potency was assessed in wound tissues contaminated by MRSA. Results: LHT-8-17 4 mg twice daily accelerated linear and planar wound healing in animals with type 1 and type 2 diabetes. The formulated topical application depressed tissue TNF-α, IL-1β, and oxidative reaction activity along with sustaining both the IL-10 concentration and antioxidant capacity. LHT-8-17 induced Ki-67 positivity of fibroblasts and pro-keratinocytes, upregulated FGFR3 gene expression, and increased tissue vascularization. The formulation possessed anti-microbial properties. Conclusions: The obtained results allow us to consider the formulation as a promising pharmacological agent for diabetic wound topical treatment.


Author(s):  
Christophe Piat ◽  
Cyrille Cazeau ◽  
Yves Stiglitz

BMJ ◽  
2011 ◽  
Vol 342 (may18 2) ◽  
pp. d874-d874
Author(s):  
A. W. N. Reid ◽  
O. P. Shelley
Keyword(s):  

1986 ◽  
Vol 26 (2) ◽  
pp. 85-92 ◽  
Author(s):  
Takayuki MIURA ◽  
Ryougo NAKAMURA ◽  
Syuuhei TORII ◽  
Kazuharu HANAKI ◽  
Yuuji YOSHIHASHI

Sign in / Sign up

Export Citation Format

Share Document