scholarly journals Quantitative Analysis of an Antioxidant Additive in Insoluble Plastics by Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) Using TiO2 Nanoparticles

2010 ◽  
Vol 58 (4) ◽  
pp. 123-127 ◽  
Author(s):  
Issey OSAKA ◽  
Koji OKUMURA ◽  
Naoki MIYAKE ◽  
Takehiro WATANABE ◽  
Kazuyoshi NOZAKI ◽  
...  
RSC Advances ◽  
2015 ◽  
Vol 5 (70) ◽  
pp. 56455-56459 ◽  
Author(s):  
Gwangbin Lee ◽  
Sang-Eun Bae ◽  
Seong Huh ◽  
Sangwon Cha

A graphene oxide embedded sol–gel (GOSG) film was utilized as a substrate for surface-assisted laser desorption/ionization mass spectrometry (SALDI MS).


The Analyst ◽  
2015 ◽  
Vol 140 (5) ◽  
pp. 1555-1565 ◽  
Author(s):  
Hani Nasser Abdelhamid ◽  
Hui-Fen Wu

GO-modified sinapinic acid was synthesized and characterized; it was then investigated for use in SALDI-MS for proteomics and pathogenic bacterial biosensing.


2021 ◽  
pp. 146906672110060
Author(s):  
Alexander A Grechnikov ◽  
Alexey S Borodkov ◽  
Yaroslav O Simanovsky ◽  
Sergey M Nikiforov

The approach to quantitative analysis by silicon Surface Assisted Laser Desorption Ionization Mass Spectrometry (Si-SALDI) is proposed. The approach is based on the new method for forming an active surface layer on a silicon substrate by exposing to laser radiation directly in the ion source of a mass spectrometer. The method can be used repeatedly on the same substrate, providing high reproducibility of its surface ionization properties and high ionization efficiency of organic compounds. Within the proposed approach, the methods of improvement of signal reproducibility are also considered, including continuous monitoring of the silicon surface ionization properties using a Knudsen effusion cell; scanning the surface of a silicon substrate with a laser beam; selecting the optimal value of laser fluence and using a reproducible sample introduction technique. It is demonstrated that this approach can be successfully applied to quantify clinically relevant concentrations of pharmaceutical drugs in extracts of blood.


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