scholarly journals Mitochondrial donation: is Australia ready?

2021 ◽  
Author(s):  
Marie A Dziadek ◽  
Carolyn M Sue
Keyword(s):  
Mitochondrial Donation

UK becomes first country to allow mitochondrial donation

BMJ ◽  
2015 ◽  
Vol 350 (feb25 14) ◽  
pp. h1103-h1103 ◽  
Author(s):  
Z. Kmietowicz
Keyword(s):  
Mitochondrial Donation

scholarly journals Public attitudes towards novel reproductive technologies: a citizens’ jury on mitochondrial donation

2019 ◽  
Vol 34 (4) ◽  
pp. 751-757 ◽  
Author(s):  
A J Newson ◽  
S de Lacey ◽  
D K Dowling ◽  
S Murray ◽  
C M Sue ◽  
...  
Keyword(s):  
Public Attitudes ◽  
Reproductive Technologies ◽  
Mitochondrial Donation

scholarly journals Mitochondrial donation in translational medicine; from imagination to reality

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Hesam Saghaei Bagheri ◽  
Farhad Bani ◽  
Savas Tasoglu ◽  
Amir Zarebkohan ◽  
Reza Rahbarghazi ◽  
...  
Keyword(s):  
Translational Medicine ◽  
Specific Activity ◽  
Current Knowledge ◽  
Review Article ◽  
Target Cells ◽  
Therapeutic Effects ◽  
Cellular Mechanisms ◽  
Pathological Conditions ◽  
Mitochondrial Transfer ◽  
Mitochondrial Donation

Abstract The existence of active crosstalk between cells in a paracrine and juxtacrine manner dictates specific activity under physiological and pathological conditions. Upon juxtacrine interaction between the cells, various types of signaling molecules and organelles are regularly transmitted in response to changes in the microenvironment. To date, it has been well-established that numerous parallel cellular mechanisms participate in the mitochondrial transfer to modulate metabolic needs in the target cells. Since the conception of stem cells activity in the restoration of tissues’ function, it has been elucidated that these cells possess a unique capacity to deliver the mitochondrial package to the juxtaposed cells. The existence of mitochondrial donation potentiates the capacity of modulation in the distinct cells to achieve better therapeutic effects. This review article aims to scrutinize the current knowledge regarding the stem cell’s mitochondrial transfer capacity and their regenerative potential.

Ethics of mitochondrial donation

The Lancet ◽  
2012 ◽  
Vol 379 (9834) ◽  
pp. 2314 ◽  
Author(s):  
The Lancet
Keyword(s):  
Mitochondrial Donation
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