Liaise with pathologists to refine understanding of the prostate‐specific antigen test

2013 ◽  
Vol 199 (10) ◽  
pp. 656-658 ◽  
Author(s):  
Kenneth A Sikaris ◽  
Bronwen A Ross ◽  
Teck Y Khong
Keyword(s):  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Antigen Test ◽  
Prostate Specific Antigen Test

scholarly journals Clinical diagnosis of prostate cancer using digital rectal examination and prostate-specific antigen tests: a systematic review and meta-analysis of sensitivity and specificity

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Nelson C. Okpua ◽  
Simon I. Okekpa ◽  
Stanley Njaka ◽  
Augusta N. Emeh
Keyword(s):  
Prostate Cancer ◽  
Prostate Specific Antigen ◽  
Sensitivity And Specificity ◽  
Specific Antigen ◽  
Digital Rectal Examination ◽  
Antigen Test ◽  
Rectal Examination ◽  
Prostate Specific Antigen Test ◽  
Prostate Cancers ◽  
Antigen Tests

Abstract Background Being diagnosed with cancer, irrespective of type initiates a serious psychological concern. The increasing rate of detection of indolent prostate cancers is a source of worry to public health. Digital rectal examination and prostate-specific antigen tests are the commonly used prostate cancer screening tests. Understanding the diagnostic accuracies of these tests may provide clearer pictures of their characteristics and values in prostate cancer diagnosis. This review compared the sensitivities and specificities of digital rectal examination and prostate-specific antigen test in detection of clinically important prostate cancers using studies from wider population. Main body We conducted literature search in PubMed, Medline, Science Direct, Wiley Online, CINAHL, Scopus, AJOL and Google Scholar, using key words and Boolean operators. Studies comparing the sensitivity and specificity of digital rectal examination and prostate-specific antigen tests in men 40 years and above, using biopsy as reference standard were retrieved. Data were extracted and analysed using Review manager (RevMan 5.3) statistical software. The overall quality of the studies was good, and heterogeneity was observed across the studies. The result comparatively shows that prostate-specific antigen test has higher sensitivity (P < 0.00001, RR 0.74, CI 0.67–0.83) and specificity (P < 0.00001, RR 1.81, CI 1.54–2.12) in the detection of prostate cancers than digital rectal examination. Conclusion Prostate-specific antigen test has higher sensitivity and specificity in detecting prostate cancers from men of multiple ethnic origins. However, combination of prostate-specific antigen test and standardized digital rectal examination procedure, along with patients history, may improve the accuracy and minimize over-diagnoses of indolent prostate cancers.

Occupation as a predictor of prostate cancer screening behaviour in Canada

2020 ◽  
Vol 27 (4) ◽  
pp. 215-222
Author(s):  
Cheryl E Peters ◽  
Paul J Villeneuve ◽  
Marie-Élise Parent
Keyword(s):  
Prostate Cancer ◽  
Cancer Screening ◽  
Prostate Specific Antigen ◽  
Prostate Cancer Screening ◽  
Specific Antigen ◽  
Digital Rectal Examination ◽  
Antigen Test ◽  
Screening Practices ◽  
Rectal Examination ◽  
Prostate Specific Antigen Test

Objectives If prostate cancer screening practices relate to occupation, this would have important implications when studying the aetiological role of workplace exposures on prostate cancer. We identified variations in screening by occupation among men in Montreal, Canada (2005–2012). Methods Prostate specific antigen testing and digital rectal examination (ever-screened and frequency of screening, previous five years) were examined among population controls from the Prostate Cancer & Environment Study. Face-to-face interviews elicited lifestyle and occupational histories. Multivariable logistic regression was used to estimate the odds of ever-screening for the longest-held occupation, adjusting for potential confounders. Negative binomial models were used to examine relationships with screening frequency. Results Among 1989 controls, 81% reported ever having had a prostate specific antigen test, and 77% a digital rectal examination. Approximately 40% of men reported having a prostate specific antigen test once a year, on average. Compared with those in management or administrative jobs, men in primary industry (odds ratio 0.26, 95% confidence interval 0.10–0.65), construction (0.44, 0.25–0.79), machining (0.45, 0.21–0.97), and teaching (0.37, 0.20–0.70) were less likely to have undergone prostate specific antigen screening. Results were similar when considering the most recent job. Conclusions Our findings highlight substantial variations in prostate cancer screening by occupation. Men in occupations where carcinogen exposures are more common are less likely to participate in prostate screening activities. This could be an important source of bias, and occupational studies of prostate cancer should account for screening practices.

10 minute consultation: High result in prostate specific antigen test

BMJ ◽  
2003 ◽  
Vol 327 (Suppl S4) ◽  
pp. 0310367
Author(s):  
M Mokete ◽  
K J O'Flynn ◽  
A R Palmer
Keyword(s):  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Antigen Test ◽  
Prostate Specific Antigen Test ◽  
High Result

scholarly journals Prostate specific antigen test uptake: a cross sectional study on elderly men in Western Iran

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Mehdi Mirzaei-Alavijeh ◽  
Farzad Jalilian ◽  
Laleh Solaimanizadeh ◽  
Abdollah Saadatfar ◽  
Shima Khashij ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Cross Sectional Study ◽  
Antigen Test ◽  
Sectional Study ◽  
Elderly Men ◽  
Cross Sectional ◽  
Western Iran ◽  
Prostate Specific Antigen Test

Liaise with pathologists to refine understanding of the prostate‐specific antigen test

2014 ◽  
Vol 200 (10) ◽  
pp. 577-578 ◽  
Author(s):  
Christopher B Del Mar ◽  
R Gordon Wright ◽  
Paul P Glasziou
Keyword(s):  
Prostate Specific Antigen ◽  
Specific Antigen ◽  
Antigen Test ◽  
Prostate Specific Antigen Test

scholarly journals Prostate-specific antigen test use reported in the 2000 National Health Interview Survey

2004 ◽  
Vol 38 (6) ◽  
pp. 732-744 ◽  
Author(s):  
Louie E Ross ◽  
Ralph J Coates ◽  
Nancy Breen ◽  
Robert J Uhler ◽  
Arnold L Potosky ◽  
...  
Keyword(s):  
Prostate Specific Antigen ◽  
National Health ◽  
National Health Interview Survey ◽  
Specific Antigen ◽  
Antigen Test ◽  
Health Interview Survey ◽  
Prostate Specific Antigen Test ◽  
Health Interview ◽  
Interview Survey ◽  
Test Use
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