Microvascular and Macrovascular Complications of Diabetes Mellitus

2005 ◽  
Vol 69 (5) ◽  
pp. 87 ◽  
Author(s):  
Keecia D. King ◽  
Jocelyn D. Jones ◽  
Jessica Warthen
Keyword(s):  
Diabetes Mellitus ◽  
Macrovascular Complications ◽  
Complications Of Diabetes ◽  
Microvascular And Macrovascular Complications

scholarly journals A prospective and observational study on complications of type 2 diabetes mellitus in correlation with body mass index

2019 ◽  
Vol 7 (12) ◽  
pp. 4723
Author(s):  
R. Siddarama ◽  
G. Thrinath ◽  
J. Bhagyasree ◽  
S. Afshaan Anjum ◽  
R. Anjanamma
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Observational Study ◽  
Diabetic Complications ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Mellitus Type ◽  
Macrovascular Complications ◽  
Complications Of Diabetes

Background: The aim of this study is to observe the prevalence of complications of diabetes mellitus (Type 2) among patients and to minimize their occurrence through patient education. The study helps to assess the clinical data of patients with diabetes mellitus (Type 2) along with the analysis of patterns, frequencies and predictive factors of microvascular, macrovascular complications and to educate and minimize the complications of diabetes mellitus among patients.Methods: Prospective and observational study was conducted among the type 2 diabetes mellitus patients at Sree Diabetes Clinic for a period of 6 months. The patients were interviewed using the patient data collection form which included demographic details, chief complaints and different diagnostic tools to detect type of complications. Both micro and macrovascular complications were evaluated.Results: A total of 150 type 2 diabetic cases were collected. Out of these 38(25.33%) patients were having BMI <25, and 112(74.67%) were having BMI ≥25 (overweight and obese). Out of 150 diabetic cases collected, a total of 131 diabetic complications were found. Out of these, 64(42.6%) were neuropathy, 3(2%) were nephropathy, 20(13.3%) were retinopathy and 17(11.3%) were having cardiovascular complications. Out of 112 patients with BMI ≥25, 60(54%) were found to have diabetic complications and out of 38 patients with BMI <25, 18(47%) were found to have diabetic complications. 90 out of 150 patients had a history of hypertension and 17 out of 150 patients had an abnormal lipid level.Conclusions: In this study, author found that obesity is a major risk factor for the development of diabetes mellitus and its complications.

scholarly journals 102 Jurnal Kesehatan Andalas. 2015; 4(1) Pola Komplikasi Kronis Penderita Diabetes Melitus Tipe 2 Rawat Inap di Bagian Penyakit Dalam RS. Dr. M. Djamil Padang Januari 2011 - Desember 2012

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Dwi Amelisa Edwina ◽  
Asman Manaf ◽  
Efrida Efrida
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Diabetic Nephropathy ◽  
Medical Record ◽  
Macrovascular Complications ◽  
Chronic Complications ◽  
Microvascular And Macrovascular Complications ◽  
Type 2 Diabetic ◽  
Diabetes Melitus

AbstrakDiabetes Melitus (DM) merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia. DM tipe 2 adalah yang paling sering ditemukan. Komplikasi kronis DM tipe 2 yaitu mikrovaskular dan makrovaskular yang dapat menurunkan kualitas hidup penderita. Tujuan penelitian ini adalah untuk memperoleh gambaran tentang insidensi penderita DM tipe 2 dengan komplikasi kronis. Penelitian deskriptif ini dilakukan dengan mengambil data pada rekam medik penderita DM tipe 2 dengan komplikasi kronis yang dirawat inap di bagian Penyakit Dalam RS.Dr. M. Djamil, Padang Januari 2011-Desember 2012. Penelitian dilakukan dari Februari 2013-April 2013 di bagian rekam medik RS. Dr. M. Djamil Padang. Data didapatkan sebanyak 261 pasien, dari jumlah tersebut didapatkan 197 pasien memiliki komplikasi kronis DM tipe 2. Data dikategorikan berdasarkan jenis komplikasi makrovaskular dan mikrovaskular. Hasil penelitian menunjukkan bahwa penderita dengan komplikasi kronis makrovaskular (66,5%) dan mikrovaskular (81,7%). Terdapat perubahan insidensi dalam dua tahun yaitu dari tahun 2011 dengan 2012. Komplikasi kronis yang paling sering terjadi adalah nefropati diabetik (42,6%) pada perempuan <60 tahun.Kata kunci: diabetes melitus, komplikasi mikrovaskular, komplikasi makrovaskularAbstractDiabetes mellitus is a group of metabolic diseases with characterized by hyperglycemia. Type 2 diabetes is the most common disease in the world. Chronic complications of type 2 diabetes are microvascular and macrovascular complications that can reduce the quality of life of patients. The objective of this study was to obtain a picture of the incidence of type 2 diabetic chronic complications. This descriptive study was conducted by taking medical record data of hospitalized type 2 diabetic patients with chronic complications inInternal Medicine Department Dr. M. Djamil hospital, Padang on January 2011-December 2012. The study was conducted from February 2013-April 2013 at the hospital medical record Dr. M. Djamil, Padang. This study was conducted on 261 patients, from that number 197 patients have chronic complications of type 2 diabetes mellitus. Data were categorized by type of macrovascular and microvascular complications.The results showed that patients with chronic complications of macrovascular (66,5%) and microvascular (81,7%). There is a change in incidence from 2011 to 2012. The most common of chronic complications is diabetic nephropathy (42.6%). Chronic microvascular and macrovascular complications are different incidence in two years, the most common is diabetic nephropathy which often occurs in women <60 years.Keyword: diabetes mellitus, microvascular complication, macrovacular complication.

scholarly journals Microvascular and Macrovascular Complications In Type 2 Diabetes Milletus

2020 ◽  
Vol 3 (2) ◽  
pp. 16-19
Author(s):  
Prakash Ajmera ◽  
P Sailaja ◽  
P Raghu Ramulu
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Risk Factor ◽  
Individual Case ◽  
Macrovascular Complications ◽  
Organ Systems ◽  
Number Of Patients ◽  
Artery Disease ◽  
Microvascular And Macrovascular Complications

Background: Long-term damage and malfunction of various organ systems can be linked to diabetes and its related complications. The objective is to evaluate the microvascular and macrovascular complications of Type 2 Diabetes Mellitus. Subjects and Methods: Patients with confirmed diabetes attending OPD were included. A detailed history is recorded for each individual case with diabetes mellitus, obesity, symptoms and family history with individuals suffering from diabetes mellitus. The physical examination was done for sensory and motor signs. Prevalence rates were typically calculated and standardized for age and sex for microvascular and macrovascular complications at baseline. Results: The overall number of patients examined was 100, of which 54% were male and 46% were female. The mean age of the patients in the sample was 53 years. The prevalence of diabetes increased with age. The prevalence of diabetes in elderly patients was maximum for 61 to 70 years of age. 29 percent of patients have a positive history of diabetes in the family. 13% of patients were smokers and all of them were males. The risk factor – Hypertension –19%, Obesity – 25% and hypercholesterolemia – 43% were present at the time of diagnosis. Conclusion: The general risk of microvascular and macrovascular problems is severe in patients with type 2 diabetes that are relatively early in the disease phase. Such findings indicate that the early risk factor may be actively changed, especially in regions with a high prevalence of complications. There are important correlations between predominant diabetes and the rising circumference and body mass index. Coronary artery disease, nephropathy and retinopathy have become particularly prevalent.

scholarly journals Diabetes and Rheumatology

2021 ◽  
pp. 445-460
Author(s):  
Alaa Monjed
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Chronic Disease ◽  
Diabetic Complications ◽  
Macrovascular Complications ◽  
Morbidity And Mortality ◽  
Insulin Deficiency ◽  
Pancreatic Insulin ◽  
Rheumatic Manifestations ◽  
Microvascular And Macrovascular Complications

AbstractDiabetes mellitus (DM) is a chronic disease characterized by persistent hyperglycaemia that happens as a result of a pancreatic insulin deficiency and/or insulin resistance. Its morbidity and mortality are primarily related to the resultant microvascular and macrovascular complications. Its prevalence has grown widely, which will result in higher rates of diabetic complications including rheumatic manifestations.

Prevention of Vascular Complications in Diabetes Mellitus Patients: Focus on the Arterial Wall

2018 ◽  
Vol 17 (1) ◽  
pp. 6-15 ◽  
Author(s):  
Mojca Lunder ◽  
Miodrag Janić ◽  
Mišo Šabovič
Keyword(s):  
Diabetes Mellitus ◽  
Arterial Wall ◽  
Microvascular Complications ◽  
Vascular Complications ◽  
Vascular Wall ◽  
Current Treatment ◽  
Macrovascular Complications ◽  
Major Adverse Cardiovascular Events ◽  
Protective Effects ◽  
Microvascular And Macrovascular Complications

In Diabetes Mellitus (DM), hyperglycaemia and insulin resistance progressively lead to both microvascular and macrovascular complications. Whereas the incidence of microvascular complications is closely related to tight glycaemic control, this does not apply to macrovascular complications. Hyperglycaemia influences many interweaving molecular pathways that initially lead to increased oxidative stress, increased inflammation and endothelial dysfunction. The latter represents the initial in both types of vascular complications; it represents the “obligatory damage” in microvascular complications development and only “introductory damage” in macrovascular complications development. Other risk factors, such as arterial hypertension and dyslipidaemia, also play an important role in the progression of macrovascular complications. All these effects accumulate and lead to functional and structural arterial wall damage. In the end, all factors combined lead to the promotion of atherosclerosis and consequently major adverse cardiovascular events. If we accept the pivotal role of vascular wall impairment in the pathogenesis and progression of microvascular and macrovascular complications, treatment focused directly on the arterial wall should be one of the priorities in prevention of vascular complications in patients with DM. In this review, an innovative approach aimed at improving arterial wall dysfunction is described, which may show efficacy in clinical studies. In addition, the potential protective effects of current treatment approaches targeting the arterial wall are summarised.

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