scholarly journals Sleep Apnea in Early Childhood Associated with Preterm Birth but Not Small for Gestational Age: A Population-Based Record Linkage Study

SLEEP ◽  
2012 ◽  
Vol 35 (11) ◽  
pp. 1475-1480 ◽  
Author(s):  
Camille H. Raynes-Greenow ◽  
Ruth M. Hadfield ◽  
Peter A. Cistulli ◽  
Jenny Bowen ◽  
Hugh Allen ◽  
...  
2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Lee K Taylor ◽  
Yuen Yi Cathy Lee ◽  
Kim Lim ◽  
Judy M Simpson ◽  
Christine L Roberts ◽  
...  

2018 ◽  
Vol 2 (1) ◽  
pp. e000316 ◽  
Author(s):  
Tomas Sjoberg Bexelius ◽  
Margareta Ahle ◽  
Anders Elfvin ◽  
Oscar Björling ◽  
Jonas F Ludvigsson ◽  
...  

Background and objectivePaediatric intestinal failure (IF) is a disease entity characterised by gut insufficiency often related to short bowel syndrome. It is commonly caused by surgical removal of a large section of the small intestine in association with necrotising enterocolitis (NEC), which usually affects premature infants. This study investigated the incidence and risk of IF in preterm infants with or without NEC.DesignA matched cohort study to investigate the incidence and risk factors for IF in a population-based setting in Sweden from 1987 to 2009 using the Swedish Patient Register.ParticipantsInfants with a diagnosis of NEC (n=720) were matched for gestational age and year of birth with reference individuals without NEC (n=3656). The study cohort was censored at death, IF or at end of follow-up (2 years of age). We calculated HRs with 95%CIs for IF using Cox regression, adjusting for pertinent perinatal factors.ResultsIF was 15 times more common in the infants with NEC compared with the reference infants (HR=7.2, with 95% CI 3.7 to 14.0). Other risk factors for IF were small for gestational age, extreme preterm birth and abdominal surgery. Neonatal mortality in infants with NEC decreased from 20.6% in 1987–1993 to 10.4% in 2007–2009.ConclusionIF was more common in the infants with NEC but was also linked to extreme preterm birth, a history of abdominal surgery and small for gestational age. IF was more common at the end of the study period, indicating that it increases when more preterm infants with NEC survive the neonatal period.


Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2573 ◽  
Author(s):  
Alexandra C. Purdue-Smithe ◽  
Tuija Männistö ◽  
Griffith A. Bell ◽  
Sunni L. Mumford ◽  
Aiyi Liu ◽  
...  

Normal maternal thyroid function during pregnancy is essential for fetal development and depends upon an adequate supply of iodine. Little is known about how iodine status is associated with preterm birth and small for gestational age (SGA) in mildly iodine insufficient populations. Our objective was to evaluate associations of early pregnancy serum iodine, thyroglobulin (Tg), and thyroid-stimulating hormone (TSH) with odds of preterm birth and SGA in a prospective, population-based, nested case-control study from all births in Finland (2012–2013). Cases of preterm birth (n = 208) and SGA (n = 209) were randomly chosen from among all singleton births. Controls were randomly chosen from among singleton births that were not preterm (n = 242) or SGA (n = 241) infants during the same time period. Women provided blood samples at 10–14 weeks’ gestation for serum iodide, Tg and TSH measurement. We used logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for preterm birth and SGA. Each log-unit increase in serum iodide was associated with higher odds of preterm birth (adjusted OR = 1.19, 95% CI = 1.02–1.40), but was not associated with SGA (adjusted OR = 1.01, 95% CI = 0.86–1.18). Tg was not associated with preterm birth (OR per 1 log-unit increase = 0.87, 95% CI = 0.73–1.05), but was inversely associated with SGA (OR per log-unit increase = 0.78, 95% CI = 0.65–0.94). Neither high nor low TSH (versus normal) were associated with either outcome. These findings suggest that among Finnish women, iodine status is not related to SGA, but higher serum iodide may be positively associated with preterm birth.


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