Sudden deterioration of CPAP adherence after myocardial infarction in a Chinese patient: potential effect of ACEI-induced airway hyperresponsiveness

2022 ◽  
Author(s):  
Yi-Hui Ou ◽  
As Tar Thant ◽  
Chi-Hang Lee
Keyword(s):  
Myocardial Infarction ◽  
Airway Hyperresponsiveness ◽  
Potential Effect ◽  
Chinese Patient ◽  
Cpap Adherence

scholarly journals Effect of regional living conditions on middle-term cardiovascular outcomes: data from prospective stage of the ESSE-RF study

2021 ◽  
Vol 20 (5) ◽  
pp. 2965
Author(s):  
S. A. Maksimov ◽  
S. A. Shalnova ◽  
V. A. Kutsenko ◽  
Yu. A. Balanova ◽  
G. A. Muromtseva ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Composite Endpoint ◽  
Potential Effect ◽  
Cardiovascular Death ◽  
Cardiovascular Outcomes ◽  
Living Conditions ◽  
Individual Risk ◽  
Middle Term ◽  
Wide Range

Aim. To assess regional living conditions with cardiovascular outcomes based on prospective stage of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation (ESSE-RF) study.Material and methods. We used data from a 3- and 5-year prospective stage of the ESSE-RF study (2012-2013). For initial screening, 16210 people aged 25-64 were included. To characterize the regions of residence, 5 regional indices (RIs) were used. The following endpoints were considered: cardiovascular death, myocardial infarction, stroke, composite endpoint (cardiovascular death + myocardial infarction + stroke). To assess the correlations, generalized estimating equations with nested data structure (individuals in the regions) were used. The studied associations were adjusted for a wide range of potential effect modifiers.Results. There are multiple direct associations of RIs with the likelihood of all endpoints. The exception was the reverse association of Industrial RI with cardiovascular death. The most stable associations regarded Mixed RI, Industrial RI and Socio-geographical RI, with a high RI significance in endpoint development, compared with well-known individual cardiovascular risk factors. Separate associations were noted for Economic RI and Demographic RI.Conclusion. The results indicate a significant contribution of a number of regional living conditions to individual risk of fatal and non-fatal cardiovascular outcomes.

scholarly journals “Summer Shift”: A Potential Effect of Sunshine on the Time Onset of ST‐Elevation Acute Myocardial Infarction

2018 ◽  
Vol 7 (8) ◽  
Author(s):  
Carlo Vittorio Cannistraci ◽  
Tuomo Nieminen ◽  
Masahiro Nishi ◽  
Levon M. Khachigian ◽  
Juho Viikilä ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Potential Effect ◽  
St Elevation ◽  
Elevation Acute Myocardial Infarction

scholarly journals On the potential effect of circadian rhythms of cardiac troponins on the diagnosis of acute myocardial infarction

2021 ◽  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Circadian Rhythms ◽  
Potential Effect ◽  
Diagnostic Process ◽  
Test Results ◽  
Laboratory Test Results ◽  
Increased Sensitivity ◽  
Cardiac Troponins

Methods for the determination of cardiac troponins have been significantly improved, facilitating further advancement of the therapeutic and diagnostic process of the cardiovascular diseases case management. In particular, acceleration of the acute myocardial infarction testing (early diagnostic algorithms: 0-1 h, 0-3 h) enabled earlier detection and choice of the optimal treatment tactics. At the same time, with the increased sensitivity in the laboratory test results interpretation, there emerged a necessity to take into account some additional factors that may affect the concentration of cardiac troponins in blood serum. Several recent studies have reported the existence of circadian rhythms in cardiac troponins. This article aims to discuss the possible mechanisms of how circadian rhythms of cardiac troponins develop and their influence on the diagnosis of acute myocardial infarction.

scholarly journals Immunomodulation and Reduction of Thromboembolic Risk in Hospitalized COVID-19 Patients: Systematic Review and Meta-Analysis of Randomized Trials

2021 ◽  
Vol 10 (22) ◽  
pp. 5366
Author(s):  
Dimitrios Sagris ◽  
Matilda Florentin ◽  
Panagiotis Tasoudis ◽  
Eleni Korompoki ◽  
Nikolaos Gatselis ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Usual Care ◽  
Thromboembolic Event ◽  
Randomized Trials ◽  
Meta Analysis ◽  
Potential Effect ◽  
Effect Estimate ◽  
Systemic Embolism ◽  
Thromboembolic Risk ◽  
Immunomodulatory Agents

Background: We aimed to investigate the potential beneficial effect of immunomodulation therapy on the thromboembolic risk in hospitalized COVID-19 patients. Methods: We searched PubMed and Scopus for randomized trials reporting the outcomes of venous thromboembolism (VTE), ischemic stroke or systemic embolism, myocardial infarction, any thromboembolic event, and all-cause mortality in COVID-19 patients treated with immunomodulatory agents. Odds ratios (OR) and 95% confidence intervals (CI) were calculated using the Mantel–Haenszel random effects method. Results: Among 8499 patients hospitalized with COVID-19, 4638 were treated with an immunomodulatory agent, 3861—with usual care only. Among the patients prescribed immunomodulatory agents, there were 1.77 VTEs per 100 patient-months compared to 2.30 among those treated with usual care (OR: 0.84, 95% CI: 0.61–1.16; I2: 0%). Among the patients who received an interleukin 6 (IL-6) antagonist, VTEs were reported in 12 among the 1075 patients compared to 20 among the 848 receiving the usual care (OR: 0.52, 95% CI: 0.22–1.20; I2: 6%). Immunomodulators as an add-on to usual care did not reduce the risk of stroke or systemic embolism (OR: 1.10, 95% CI: 0.50–2.40; I2: 0%) or of myocardial infarction (OR: 1.06, 95% CI: 0.47–2.39; I2: 0%) and there was a nonsignificant reduction in any thromboembolic event (OR: 0.86, 95% CI: 0.65–1.14; I2: 0%). Conclusions: We did not identify a statistically significant effect of immunomodulation on prevention of thromboembolic events in COVID-19. However, given the large effect estimate for VTE prevention, especially in the patients treated with IL-6 antagonists, we cannot exclude a potential effect of immunomodulation.

An electron microscopic study of the intra-myocardial lesions in cases of acute myocardial infarction

1978 ◽  
Vol 36 (2) ◽  
pp. 484-485
Author(s):  
Masahiro Ono ◽  
Kaoru Aihara ◽  
Gompachi Yajima
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Vessels ◽  
Vascular Wall ◽  
Vascular Changes ◽  
Electron Microscopic ◽  
Main Trunk ◽  
Mechanical Destruction ◽  
Transmission Electron ◽  
Myocardial Lesions

The pathogenesis of the arteriosclerosis in the acute myocardial infarction is the matter of the extensive survey with the transmission electron microscopy in experimental and clinical materials. In the previous communication,the authors have clarified that the two types of the coronary vascular changes could exist. The first category is the case in which we had failed to observe no occlusive changes of the coronary vessels which eventually form the myocardial infarction. The next category is the case in which occlusive -thrombotic changes are observed in which the myocardial infarction will be taken placed as the final event. The authors incline to designate the former category as the non-occlusive-non thrombotic lesions. The most important findings in both cases are the “mechanical destruction of the vascular wall and imbibition of the serous component” which are most frequently observed at the proximal portion of the coronary main trunk.

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