scholarly journals Expiratory Positive Airway Pressure for Sleep Apnea after Stroke: A Randomized, Crossover Trial

2016 ◽  
Vol 12 (09) ◽  
pp. 1233-1238 ◽  
Author(s):  
Natalie C. Wheeler ◽  
Jeffrey J. Wing ◽  
Louise M. O'Brien ◽  
Rebecca Hughes ◽  
Teresa Jacobs ◽  
...  
Keyword(s):  
Sleep Apnea ◽  
Airway Pressure ◽  
Crossover Trial ◽  
Positive Airway Pressure ◽  
Randomized Crossover Trial ◽  
Expiratory Positive Airway Pressure

scholarly journals Effects of Pressure Control Device (SensAwake™) on Obstructive Sleep Apnea (OSA) Patients Who Remove the Mask for Unknown Reasons during Automatic Continuous Positive Airway Pressure (Auto-CPAP) Therapy: A Prospective Randomized Crossover Trial

Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 915
Author(s):  
Yen-Lung Chen ◽  
Li-Pang Chuang ◽  
Shih-Wei Lin ◽  
Hung-Yu Huang ◽  
Geng-Hao Liu ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Sleep Quality ◽  
Airway Pressure ◽  
Crossover Trial ◽  
Positive Airway Pressure ◽  
Cpap Therapy ◽  
Randomized Crossover Trial ◽  
Obstructive Sleep

Backgroundand Objectives: Obstructive sleep apnea (OSA) patients may remove their mask unconsciously during automatic continuous positive airway pressure (Auto-CPAP) therapy and therefore cannot receive good treatment. The discomfort from the airflow of Auto-CPAP may be one reason for interrupted sleep. Sens Awake (SA) can detect the arousal and lower the pressure to prevent patients from fully awakening from sleep. Materials and Methods: To evaluate the effect of SA, we designed a prospective, randomized, crossover trial comparing Auto-CPAP with and without SA on Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI), Nasal Obstruction Symptom Evaluation (NOSE) Scale and recorded data from the auto-CPAP machine. Results: In the 25 patients who completed the study, the gender, age, body mass index, neck circumference, polysomnography data, and previous CPAP use were not significantly different between the two arms. The average and 90th percentile pressures were significantly lower during SA on (SA on vs. off: 6.9 ± 2.7 vs. 7.3 ± 2.6 [p = 0.032] and 8.6 ± 3.0 vs. 9.2 ± 2.9 [p = 0.002], respectively). The time used, days used, compliance, average and 90th percentile leaks, and the residual Apnea-Hypopnea Index (AHI) were not significantly changed between the SA on-and-off. Based on the subjective evaluation, PSQI, ESS, and NOSE were not significantly different between the SA on-and-off; however, based on additional analyses which were compared with baseline data, the ESS was significantly lower when the SA was on (SA on vs. baseline: 11.1 ± 6.1 vs. 13.2 ± 6.0 [p = 0.023]). Conclusions: CPAP therapy with or without two weeks of the SA had a similar effect on CPAP use, sleep quality, daytime sleepiness, and nasal obstruction. The SA may have a tendency to improve daytime sleepiness, but needs further study with a longer duration of treatment.

Randomized Placebo-controlled Crossover Trial of Continuous Positive Airway Pressure for Mild Sleep Apnea/Hypopnea Syndrome

1999 ◽  
Vol 159 (2) ◽  
pp. 461-467 ◽  
Author(s):  
HEATHER M. ENGLEMAN ◽  
RUTH N. KINGSHOTT ◽  
PETER K. WRAITH ◽  
THOMAS W. MACKAY ◽  
IAN J. DEARY ◽  
...  
Keyword(s):  
Sleep Apnea ◽  
Continuous Positive Airway Pressure ◽  
Airway Pressure ◽  
Crossover Trial ◽  
Positive Airway Pressure ◽  
Hypopnea Syndrome
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