scholarly journals Updated Adaptive Servo-Ventilation Recommendations for the 2012 AASM Guideline: “The Treatment of Central Sleep Apnea Syndromes in Adults: Practice Parameters with an Evidence-Based Literature Review and Meta-Analyses”

2016 ◽  
Vol 12 (05) ◽  
pp. 757-761 ◽  
Author(s):  
R. Nisha Aurora ◽  
Sabin R. Bista ◽  
Kenneth R. Casey ◽  
Susmita Chowdhuri ◽  
David A. Kristo ◽  
...  
SLEEP ◽  
2012 ◽  
Vol 35 (1) ◽  
pp. 17-40 ◽  
Author(s):  
R. Nisha Aurora ◽  
Susmita Chowdhuri ◽  
Kannan Ramar ◽  
Sabin R. Bista ◽  
Kenneth R. Casey ◽  
...  

2009 ◽  
Vol 4 ◽  
pp. S67
Author(s):  
Shingo Nakagawa ◽  
Yoshiko Nakagawa ◽  
Keisuke Ishimaru ◽  
Haruo Nakagawa ◽  
Takatoshi Kasai ◽  
...  

Author(s):  
Shi Nee Tan ◽  
Baharudin Abdullah

: Sleep-disordered breathing (SDB) is now a significant health problem in today's culture. It ranges from a spectrum of abnormal conditions during sleep from the primary snorer to mild, moderate, or severe obstructive sleep apnea (OSA). SDB also comprises other conditions, such as sleep-related hypoventilation, sleep-related hypoxemia, and central sleep apnea syndromes. One of the components of the pathophysiology of OSA that remain unclear is the association of allergic rhinitis (AR) in the evolution of OSA. Several studies relate OSA and AR's co-existence in the common clinical practice, but its correlation was not clear. This review article aimed to review the relationship between OSA and AR in terms of the role of chemical mediators and pathophysiological and the effect of AR treatment in support of OSA. The symptoms of AR further accelerate the clinical progression to OSA development. Inflammatory mediators such as histamine, cysteinyl leukotrienes, and interleukins are found at a high level in AR, which can aggravate AR symptoms such as nasal obstruction, rhinorrhea, and itchiness, which can then lead to sleep disruption in OSA patients. In addition, OSA patients also have increased chemical mediators such as tumor necrosis factor, interleukin 6, and 1, which would activate the T helper 2 phenotypes that can aggravate AR symptoms. This vicious cycle can potentiate each other and worsen the condition. Few studies have shown that treatment of AR can improve OSA, especially the use of intranasal steroid and leukotriene receptor antagonists. A detailed evaluation of rhinitis symptoms should be made for those OSA patients so that they can benefit not only from the improvement of AR but also the good sleep quality.


2013 ◽  
Vol 14 (4) ◽  
pp. 296-300 ◽  
Author(s):  
Emilia D’Elia ◽  
Emilio Vanoli ◽  
Maria T. La Rovere ◽  
Francesco Fanfulla ◽  
Alessandra Maggioni ◽  
...  

2014 ◽  
Vol 10 (1) ◽  
pp. 57 ◽  
Author(s):  
Roopika Reddy, MD ◽  
David Adamo, RPSGT ◽  
Thomas Kufel, MD ◽  
Jahan Porhomayon, MD ◽  
Ali A. El-Solh, MD, MPH

Objective: To systematically review the various modalities of positive airway pressure (PAP) in the treatment of opioid-related central sleep apnea (CSA).Design: Systematic review.Interventions: MEDLINE, the Cochrane Library, and EMBASE were screened through March 2013 to identify articles which investigated treatment of opioid-related CSA with PAP. Eligible articles were identified in a staged process and were assessed by two investigators independently. The methodological quality of the reporting of eligible articles was assessed using a set of questions addressing both general and statistical methodologies.Results: Five articles met the inclusion criteria for a total of 127 patients. All patients had been on opioids for at least 6 months. The dose ranged from 10 mg to 450 mg daily of morphine equivalent dose. Continuous positive airway pressure (CPAP) was proven mostly ineffective in reducing central apneic events. Bilevel positive airway pressure (BiPAP) with and without supplemental oxygen achieved elimination of central apneas in 62 percent of patients. Adaptive servo ventilation (ASV) yielded conflicting results with 58 percent of participants attaining a central apnea index <10 per hour. The presence of ataxic breathing predicted poor response to PAP.Conclusions: The available evidence on the efficacy of PAP in opioid-related CSA is inconclusive. With the increasing use of opioids, further studies are needed to assess optimal PAP therapy and predictors of success in this group of patients.


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