scholarly journals Gender Differences in Regional Brain Activity in Patients with Chronic Primary Insomnia: Evidence from a Resting-State fMRI Study

2016 ◽  
Vol 12 (03) ◽  
pp. 363-374 ◽  
Author(s):  
Xi-Jian Dai ◽  
Xiao Nie ◽  
Xuming Liu ◽  
Li Pei ◽  
Jian Jiang ◽  
...  
Keyword(s):  
Gender Differences ◽  
Resting State ◽  
Brain Activity ◽  
Resting State Fmri ◽  
Primary Insomnia ◽  
Regional Brain ◽  
Fmri Study ◽  
Regional Brain Activity

Distinguishing hypochondriasis and schizophrenia using regional homogeneity: a resting-state fMRI study and support vector machine analysis

2021 ◽  
pp. 1-29
Author(s):  
Kangyu Jin ◽  
Zhe Shen ◽  
Guoxun Feng ◽  
Zhiyong Zhao ◽  
Jing Lu ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Resting State ◽  
Parietal Lobe ◽  
Brain Activity ◽  
Resting State Fmri ◽  
Brain Regions ◽  
Regional Homogeneity ◽  
Middle Temporal Gyrus ◽  
Support Vector ◽  
Fmri Study

Abstract Objective: A few former studies suggested there are partial overlaps in abnormal brain structure and cognitive function between Hypochondriasis (HS) and schizophrenia (SZ). But their differences in brain activity and cognitive function were unclear. Methods: 21 HS patients, 23 SZ patients, and 24 healthy controls (HC) underwent Resting-state functional magnetic resonance imaging (rs-fMRI) with the regional homogeneity analysis (ReHo), subsequently exploring the relationship between ReHo value and cognitive functions. The support vector machines (SVM) were used on effectiveness evaluation of ReHo for differentiating HS from SZ. Results: Compared with HC, HS showed significantly increased ReHo values in right middle temporal gyrus (MTG), left inferior parietal lobe (IPL) and right fusiform gyrus (FG), while SZ showed increased ReHo in left insula, decreased ReHo values in right paracentral lobule. Additionally, HS showed significantly higher ReHo values in FG, MTG and left paracentral lobule but lower in insula than SZ. The higher ReHo values in insula were associated with worse performance in MCCB in HS group. SVM analysis showed a combination of the ReHo values in insula and FG was able to satisfactorily distinguish the HS and SZ patients. Conclusion: our results suggested the altered default mode network (DMN), of which abnormal spontaneous neural activity occurs in multiple brain regions, might play a key role in the pathogenesis of HS, and the resting-state alterations of insula closely related to cognitive dysfunction in HS. Furthermore, the combination of the ReHo in FG and insula was a relatively ideal indicator to distinguish HS from SZ.

Altered baseline brain activity in type 2 diabetes: A resting-state fMRI study

2013 ◽  
Vol 38 (11) ◽  
pp. 2493-2501 ◽  
Author(s):  
Wenqing Xia ◽  
Shaohua Wang ◽  
Zilin Sun ◽  
Feng Bai ◽  
Yi Zhou ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Resting State ◽  
Brain Activity ◽  
Resting State Fmri ◽  
Fmri Study

scholarly journals Aberrant baseline brain activity in psychogenic erectile dysfunction patients: a resting state fMRI study

2017 ◽  
Vol 12 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Chenwang Jin ◽  
Min Guan ◽  
Minghao Dong ◽  
Jia Wu ◽  
Zhen He ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Resting State ◽  
Brain Activity ◽  
Resting State Fmri ◽  
Fmri Study
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