scholarly journals Relationship between Sleep Apnea, Fat Distribution, and Insulin Resistance in Obese Children

2011 ◽  
Vol 07 (03) ◽  
pp. 268-273 ◽  
Author(s):  
Craig A. Canapari ◽  
Alison G. Hoppin ◽  
T. Bernard Kinane ◽  
Bijoy J. Thomas ◽  
Martin Torriani ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Sleep Apnea ◽  
Fat Distribution ◽  
Obese Children

scholarly journals LDL particle size, fat distribution and insulin resistance in obese children

2005 ◽  
Vol 60 (3) ◽  
pp. 416-420 ◽  
Author(s):  
M Miyashita ◽  
T Okada ◽  
Y Kuromori ◽  
K Harada
Keyword(s):  
Insulin Resistance ◽  
Particle Size ◽  
Fat Distribution ◽  
Obese Children ◽  
Ldl Particle Size

scholarly journals 0868 THE ASSOCIATION BETWEEN OBSTRUCTIVE SLEEP APNEA WITH INSULIN RESISTANCE IN OBESE CHILDREN

SLEEP ◽  
2017 ◽  
Vol 40 (suppl_1) ◽  
pp. A322-A322
Author(s):  
R Siriwat ◽  
L wang ◽  
J Bena ◽  
V Shah ◽  
S Ibrahim
Keyword(s):  
Insulin Resistance ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obese Children ◽  
Obstructive Sleep

scholarly journals Importance of Android/Gynoid Fat Ratio in Predicting Metabolic and Cardiovascular Disease Risk in Normal Weight as well as Overweight and Obese Children

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Lennie Samsell ◽  
Michael Regier ◽  
Cheryl Walton ◽  
Lesley Cottrell
Keyword(s):  
Insulin Resistance ◽  
Cardiovascular Disease ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Fat Distribution ◽  
Normal Weight ◽  
Obese Children ◽  
Vldl Cholesterol ◽  
Body Sizes ◽  
Gynoid Fat

Numerous studies have shown that android or truncal obesity is associated with a risk for metabolic and cardiovascular disease, yet there is evidence that gynoid fat distribution may be protective. However, these studies have focused on adults and obese children. The purpose of our study was to determine if the android/gynoid fat ratio is positively correlated with insulin resistance, HOMA2-IR, and dislipidemia in a child sample of varying body sizes. In 7–13-year-old children with BMI percentiles ranging from 0.1 to 99.6, the android/gynoid ratio was closely associated with insulin resistance and combined LDL + VLDL-cholesterol. When separated by sex, it became clear that these relationships were stronger in boys than in girls. Subjects were stratified into BMI percentile based tertiles. For boys, the android/gynoid ratio was significantly related to insulin resistance regardless of BMI tertile with and LDL + VLDL in tertiles 1 and 3. For girls, only LDL + VLDL showed any significance with android/gynoid ratio and only in tertile 2. We conclude that the android/gynoid fat ratio is closely associated with insulin resistance and LDL + VLDL-, “bad,” cholesterol in normal weight boys and may provide a measurement of metabolic and cardiovascular disease risk in that population.

scholarly journals Obstructive Sleep Apnea as a Risk Factor of Insulin Resistance in Nondiabetic Adults

Life ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 50
Author(s):  
Monika Michalek-Zrabkowska ◽  
Piotr Macek ◽  
Helena Martynowicz ◽  
Pawel Gac ◽  
Grzegorz Mazur ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Obstructive Sleep Apnea ◽  
Risk Factor ◽  
Sleep Apnea ◽  
Glucose Concentration ◽  
Insulin Concentration ◽  
Fasting Insulin ◽  
Sleep Habits ◽  
Obstructive Sleep

Objective: The aim of this research was to assess the relationship between prevalence and severity of obstructive sleep apnea (OSA) and insulin resistance among patients with increased risk of OSA without diabetes mellitus. Method and materials: our study group involved 102 individuals with suspected OSA, mean age 53.02 ± 12.37 years. Data on medical history, medication usage, sleep habits, sleep quality and daytime sleepiness, were obtained using questionnaires. All patients underwent standardized full night polysomnography. Serum fasting insulin and glucose concentration were analyzed, the homeostatic model assessment-insulin resistance (HOMA-IR) index was calculated. Results: polysomnographic study indicated that in the group with OSA mean values of apnea–hypopnea index (AHI), oxygen desaturation index (ODI), duration of SpO2 < 90% and average desaturation drop were significantly higher compared to the group without OSA, while the minimum SpO2 was significantly lower. The carbohydrate metabolism parameters did not differ within those groups. Significantly higher fasting insulin concentration and HOMA-IR index were found in the group with AHI ≥ 15 compared to the group with AHI < 15 and in the group with AHI ≥ 30 compared to the group with AHI < 30. Higher AHI and ODI were independent risk factors for higher fasting insulin concentration and higher HOMA-IR index. Increased duration of SpO2 < 90% was an independent risk factor for higher fasting glucose concentration. Conclusions: Individuals with moderate to severe OSA without diabetes mellitus had a higher prevalence of insulin resistance.

Sign in / Sign up

Export Citation Format

Share Document