scholarly journals Potential Association between Insulin-like Growth Factor-1 Receptor Activity and Surf Clam Spisula sachalinensis Larvae Survival

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Азимова Ф. В. ◽  
Ходжаева М. Б.

This article is devoted to the study of coregulators of androgen receptor activity in the pathogenesis of androgen-dependent dermatopathies, in particular, for acne - 25-OH-VD, cytochrome p 450 (17-alpha hydroxylase), insulin-like growth factor. There were 46 patients with acne from 14 to 25 years of age under observation. The results of studies showed significant violations of the enzymes regulating androgen receptors - 25-OH-VD, cytochrome p 450 (17-alpha hydroxylase), as well as the growth factor (insulin-like growth factor), which are important in the pathogenesis of fast non-genomic molecular cell reactions of peripheral androgens metabolism with acne.


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