scholarly journals Effects of Dietary Cimetidine, a Cytochrome P450 Inhibitor, on the Benzo[a]pyrene-induced Lipid Peroxidation of Liver in Olive Flounder, Paralichthys olivaceus

2002 ◽  
Vol 5 (1) ◽  
pp. 28-31
Author(s):  
Chun Soo Kim ◽  
Jae Hyuck Jung ◽  
Ki Hong Kim
Keyword(s):  
Lipid Peroxidation ◽  
Cytochrome P450 ◽  
Paralichthys Olivaceus ◽  
Olive Flounder ◽  
Olive Flounder Paralichthys Olivaceus

Roles of forkhead box protein L2 (foxl2) during gonad differentiation and maintenance in a fish, the olive flounder (Paralichthys olivaceus)

2019 ◽  
Vol 31 (11) ◽  
pp. 1742 ◽  
Author(s):  
Zhaofei Fan ◽  
Yuxia Zou ◽  
Dongdong Liang ◽  
Xungang Tan ◽  
Shuang Jiao ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Cytochrome P450 ◽  
High Temperature ◽  
Paralichthys Olivaceus ◽  
Sex Reversal ◽  
Olive Flounder ◽  
Gonad Differentiation ◽  
Forkhead Box ◽  
Cytochrome P450 Family ◽  
Olive Flounder Paralichthys Olivaceus

As an important maricultured fish, the olive flounder Paralichthys olivaceus shows sex-dimorphic growth. Thus, the molecular mechanisms involved in sex control in P. olivaceus have attracted researchers’ attention. Among the sex-related genes, forkhead box protein L2 (foxl2) exhibits significant sex-dimorphic expression patterns and plays an important role in fish gonad differentiation and development. The present study first investigated the expression levels and promoter methylation dynamics of foxl2 during flounder gonad differentiation under treatments of high temperature and exogenous 17β-oestradiol (E2). During high temperature treatment, the expression of flounder foxl2 may be repressed via maintenance of DNA methylation. Then, flounder with differentiated testis at Stages I–II were treated with exogenous 5ppm E2 or 5ppm E2+150ppm trilostane (TR) to investigate whether exogenous sex hormones could induce flounder sex reversal. The differentiated testis exhibited phenotypic variations of gonadal dysgenesis with upregulation of female-related genes (foxl2 and cytochrome P450 family 19 subfamily A (cyp19a)) and downregulation of male-related genes (cytochrome P450 family 11 subfamily B member 2 (cyp11b2), doublesex- and mab-3 related transcription factor 1 (dmrt1), anti-Mullerian hormone (amh) and SRY-box transcription factor 9 (sox9)). Furthermore, a cotransfection assay of the cells of the flounder Sertoli cell line indicated that Foxl2 was able alone or with nuclear receptor subfamily 5 group A member 2 (Nr5a2) jointly to upregulate expression of cyp19a. Moreover, Foxl2 and Nr5a2 repressed the expression of dmrt1. In summary, Foxl2 may play an important role in ovarian differentiation by maintaining cyp19a expression and antagonising the expression of dmrt1. However, upregulation of foxl2 is not sufficient to induce the sex reversal of differentiated testis.

scholarly journals Mealworm, Tenebrio molitor, as a feed ingredient for juvenile olive flounder, Paralichthys olivaceus

2021 ◽  
Vol 20 ◽  
pp. 100747
Author(s):  
Seong-Mok Jeong ◽  
Sanaz Khosravi ◽  
Kye-Yoon Yoon ◽  
Kang-Woong Kim ◽  
Bong-Joo Lee ◽  
...  
Keyword(s):  
Paralichthys Olivaceus ◽  
Tenebrio Molitor ◽  
Olive Flounder ◽  
Feed Ingredient ◽  
Olive Flounder Paralichthys Olivaceus

Evaluation of the three different sources of dietary starch in an extruded feed for juvenile olive flounder, Paralichthys olivaceus

Aquaculture ◽  
2021 ◽  
Vol 533 ◽  
pp. 736242
Author(s):  
Seong-Mok Jeong ◽  
Sanaz Khosravi ◽  
Sang Yoon Lee ◽  
Kang-Woong Kim ◽  
Bong-Joo Lee ◽  
...  
Keyword(s):  
Paralichthys Olivaceus ◽  
Olive Flounder ◽  
Extruded Feed ◽  
Dietary Starch ◽  
Different Sources ◽  
Olive Flounder Paralichthys Olivaceus
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