scholarly journals Purification of EPA Ethyl Ester from Fish Oil with a Supercritical CO2 Temperature Gradient Rectification Column.

1997 ◽  
Vol 46 (3) ◽  
pp. 331-340 ◽  
Author(s):  
Hiromasa SUZUKI ◽  
JUN Chen ◽  
Tadafumi ADSCHIRI ◽  
Hiroshi INOMATA ◽  
Kunio ARAI
Keyword(s):  
Temperature Gradient ◽  
Fish Oil ◽  
Ethyl Ester ◽  
Supercritical Co2 ◽  
Rectification Column

Preparation of eicosapentaenoic acid ethyl ester from fish oil ethyl esters by continuous batch chromatography

2019 ◽  
Vol 42 (24) ◽  
pp. 3697-3702
Author(s):  
Yanmei Li ◽  
Lei Zhao ◽  
Xiaolei Huang ◽  
Liguang Zhang ◽  
Jingjing Li ◽  
...  
Keyword(s):  
Eicosapentaenoic Acid ◽  
Fish Oil ◽  
Ethyl Ester ◽  
Acid Ethyl Ester ◽  
Ethyl Esters ◽  
Eicosapentaenoic Acid Ethyl Ester

Individual effects of dietary EPA and DHA on the functioning of the isolated working rat heart

1998 ◽  
Vol 76 (7-8) ◽  
pp. 728-736 ◽  
Author(s):  
J -P Sergiel ◽  
L Martine ◽  
D Raederstorff ◽  
A Grynberg ◽  
L Demaison
Keyword(s):  
Fatty Acids ◽  
Cardiac Function ◽  
Polyunsaturated Fatty Acids ◽  
Fish Oil ◽  
Ethyl Ester ◽  
Coronary Flow ◽  
Aortic Flow ◽  
Pufa Ratio ◽  
Postischemic Reperfusion ◽  
Developed Pressure

The aim of this study was to evaluate the effects of dietary pure eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the physiology of the heart in normoxic conditions and during postischemic reperfusion. These effects were compared with those of dietary n-6 polyunsaturated fatty acids (PUFA). Rats were fed a diet containing either sunflower seed oil (75 g·kg-1, SSO group), or a mixture of EPA (20:5 n-3) ethyl ester and SSO (10:90, EPA group), or a mixture of DHA (22:6 n-3) ethyl ester and SSO (10:90, DHA group), or a mixture of EPA + DHA ethyl esters and SSO (4.2:5.8:90, e+D group) for 6 weeks. The hearts were then perfused according to the working mode. The perfusion was maintained either in normoxic conditions or stopped for 17 min (global zero-flow ischemia) and restored for 33 min (reperfusion). The aortic and coronary flows, aortic developed pressure, and electrocardiogram were continuously monitored. When rats were fed a diet containing either EPA and (or) DHA, the n-6/n-3 PUFA ratio of cardiac phospholipids decreased. The proportion of arachidonic acid was reduced more with DHA than dietary EPA. In the EPA group, the percentage of DHA was lower than in the DHA group, but the percentage of EPA and docosapentaenoic acid (22:5 n-3) was higher. These changes in membrane fatty acid composition altered the cardiac function. In normoxic conditions, the coronary flow was higher in the SSO group than in the DHA and EPA groups. The heart rate was lower in the DHA and e+D groups than in the EPA and SSO groups. The aortic flow, cardiac output, and aortic developed pressure were not affected. During postischemic reperfusion, the recovery of aortic flow, coronary flow, and aortic developed pressure was similar in the four groups. A slightly improved recovery of cardiac function was noticed in the EPA group, but the difference was not significant. Feeding rats 5% fish oil + 5% SSO instead of 10% SSO for 8 weeks increased the incorporation of EPA in cardiac phospholipids and favored the recovery (+120%) of aortic flow during postischemic reperfusion. In conclusion, the beneficial effect of dietary fish oil on the recovery of cardiac pump activity during reperfusion was not observed with DHA or EPA alone. It appears to be positively related to the accumulation of EPA in membrane phospholipids. The dietary conditions favouring EPA accumulation remain to be determined.Key words: dietary polyunsaturated fatty acids, myocardial ischemia, reperfusion.

scholarly journals Effect of Oxidative Sardin Fish Oil for Food Utilization

2017 ◽  
Vol 20 (2) ◽  
pp. 275
Author(s):  
Pitria Andriyani ◽  
Tati Nurhayati ◽  
Sugeng Heri Suseno
Keyword(s):  
Fatty Acid ◽  
Fish Oil ◽  
Palmitic Acid ◽  
Ethyl Ester ◽  
Fish Meal ◽  
P Value ◽  
Physical Parameters ◽  
Food Utilization ◽  
Refined Oil ◽  
Predominant Fatty Acid

Sardine is an economic fish industry product in Indonesia. Sardin fish oil of fish meal by-product can be processed into ethyl ester as a food grade product. The purpose of this study were to determine the chemical and physical the best ethyl ester of Semirefined and refined oil from sardine fish meal by-products. Results showed that heavy metals detected was cadmium (Cd) value, i.e. 0.02 ppm. SFA content of crude oil sardines was 29.39% with palmitic acid (16.24%) as the predominant fatty acids. The MUFA content amounted to 14.87% with palmitic acid as the predominant fatty acid (5.76%). The PUFA content were 35.47% with DHA (17.07%) as the predominant fatty acid, while EPA amounted to 13.82%. Semirefined oil  transformed into Semirefined ethyl ester oil was the best on oxidative and physical parameters. Oxidation process produced Semirefined ethyl ester with 1.50±0.00 mEq/kg peroxide value (PV), 0.90±0.15% fatty<br />acids (% FFA), 5.46±0.32 mEq/kg Anisidin p-value (p-AV), 8.46±0.32 mEq/kg oxidation (TOTOKS), 62.15±0.27%T viscosity and and 5.65±0,26 cP clarity.

Recent Advances in Supercritical CO2 Fracturing: New Theory, New Technology, and Application

2021 ◽  
Author(s):  
Wenguang Duan ◽  
Baojiang Sun ◽  
Deng Pan ◽  
Jianchun Xu ◽  
Jian Liu
Keyword(s):  
Temperature Gradient ◽  
Phase Behavior ◽  
Supercritical Co2 ◽  
Phase Control ◽  
Control Model ◽  
Injection Rate ◽  
Shale Oil ◽  
Fracturing Fluid ◽  
Fluid Filtration ◽  
Injection Temperature

Abstract The shale oil reservoir in Jimusaer has the characteristics of low porosity and low permeability, resulting in significant resistance in oil flow compared with conventional oil reservoirs. Fracturing is needed to increase shale oil production. Supercritical CO2 (SC-CO2) is an ideal choice for fracturing fluid due to its unique physical and chemical properties. SC-CO2 fracturing is able to make CO2 flow into microfractures and greatly reduce the pumping pressure. New progress has been made in the application of the supercritical CO2 fracturing technology in Jimusaer. A phase control model of SC-CO2 fracturing as a function of temperature and pressure is established, which takes into account the SC-CO2 features, intrinsic energy, flow behavior in fracture and fluid filtration. In this paper, the influences of injection pressure and temperature, injection rate, temperature-pressure field, temperature gradient, and phase behavior are analyzed extensively, in addition, the phase control model and its chart of fracture are presented. The proppant accumulation height reduces by a small amount with the increase of the fracturing fluid injection rate. It is necessary to improve the proppant pumping technology by the sand embankment section and proppant concentration. The liquid transforms into supercritical fluid, when flowing in wellbores and fractures. Different fractures have different phase points, and a lower injection temperature is affected by higher injection rate, lower temperature gradient and closer position from transformation point to the end of fracture. Therefore, in order to achieve a better fracturing effect, the injection temperature, pressure, and rate need to be optimized by surface equipment according to the reservoir conditions, to control the phase behavior of CO2. We built a phase control model for the SC-CO2 fracturing technology, which considers temperature control. We also developed some new techniques to improve SC-CO2 fracturing which is critically needed in the Jimusaer oilfield.

Comparative studies of DHA-enriched phosphatidylcholine and recombination of DHA-ethyl ester with egg phosphatidylcholine on ameliorating memory and cognitive deficiency in SAMP8 mice

2019 ◽  
Vol 10 (2) ◽  
pp. 938-950 ◽  
Author(s):  
Cheng-Cheng Wang ◽  
Ying Guo ◽  
Miao-Miao Zhou ◽  
Chang-Hu Xue ◽  
Yao-Guang Chang ◽  
...  
Keyword(s):  
Fish Oil ◽  
Ethyl Ester ◽  
Comparative Studies ◽  
Memory Loss ◽  
Commercial Fish ◽  
Age Related ◽  
Cognitive Deficiency ◽  
Samp8 Mice

DHA-PLs (DHA-PC) could not be substituted by recombination of commercial fish oil with DHA-free PC in alleviating age-related memory loss and cognitive deficiency in SAMP8 mice.

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