scholarly journals Secondary Metabolites of an of Streptomyces griseorubens Isolate Are Predominantly Pyrrole- and Linoleic-acid like Compounds

2020 ◽  
Vol 69 (10) ◽  
pp. 1273-1280 ◽  
Author(s):  
Serap Çetinkaya ◽  
Ali Fazıl Yenidünya ◽  
Kubilay Arslan ◽  
Dönsel Arslan ◽  
Özgül Doğan ◽  
...  
Keyword(s):  
Linoleic Acid ◽  
Secondary Metabolites ◽  
Streptomyces Griseorubens

Secondary metabolites with nematicidal and antimicrobial activity from nematophagous fungi and Ascomycetes

1995 ◽  
Vol 73 (S1) ◽  
pp. 932-939 ◽  
Author(s):  
H. Anke ◽  
M. Stadler ◽  
A. Mayer ◽  
O. Sterner
Keyword(s):  
Linoleic Acid ◽  
Secondary Metabolites ◽  
Biosynthetic Pathway ◽  
Nematophagous Fungi ◽  
Submerged Cultures ◽  
Daldinia Concentrica ◽  
Antimicrobial Metabolites ◽  
Natural Nematicides ◽  
Arthrobotrys Conoides ◽  
New Metabolites

Screening of nematode-trapping fungi for antimicrobial and nematicidal activities gave three new antimicrobial metabolites from cultures of five Arthrobotrys strains. The compounds exhibited no nematicidal activities towards Caenorhabditis elegans and Meloidogyne incognita. From trap-forming submerged cultures of Arthrobotrys conoides, linoleic acid was isolated as a nematicidal principle. Its production increased with the number of traps formed in both Arthrobotrys oligospora and Arthrobotrys conoides. Nematoctonus robustus and Nematoctonus concurrens produced pleurotin, dihydropleurotinic acid, and leucopleurotin, metabolites previously isolated from cultures of Hohenbuehelia species, suggesting that the same biosynthetic pathways function in both the teleomorph and anamorph. Several strains of Ascomycetes had nematicidal activities; linoleic acid was responsible for the activity in cultures of a Chlorosplenium species, 14-epicochlioquinone B in cultures of Neobulgaria pura, and two naphthalenes derived from the melanin biosynthetic pathway in Daldinia concentrica. 5-Pentyl-2-furaldehyde, previously known as a metabolite from a Basidiomycete, was produced by an unidentified Australian Ascomycete. More than 30 mostly new metabolites have been isolated from cultures of Lachnum papyraceum, many being chlorinated. Under different conditions the fungus incorporated bromine instead of chlorine. Key words: nematophagous fungi, natural nematicides, linoleic acid, chlorinated secondary metabolites.

scholarly journals Secondary Metabolites from Asperula lutea subsp. rigidula

2011 ◽  
Vol 6 (2) ◽  
pp. 1934578X1100600
Author(s):  
Olga Tzakou ◽  
Konstantinos Lempesis ◽  
Anargyros Loukis
Keyword(s):  
Fatty Acids ◽  
Linoleic Acid ◽  
Secondary Metabolites ◽  
Palmitic Acid ◽  
Chlorogenic Acid ◽  
Methanolic Extract ◽  
Polar Fraction ◽  
Ethyl Esters ◽  
Endemic Plant ◽  
Aerial Parts

From the aerial parts of Asperula lutea subsp. rigidula (Halacsy) Ehrend., an endemic plant of southeastern Greece, nine known compounds, β-sitosterol, geniposidic acid, deacetyl-asperuloside, scandoside, chlorogenic acid, quercetin, hyperin, isoquercitrin and rutin, were isolated. From the analysis of a non polar fraction of the methanolic extract by means of GC and GC-MS, eighteen compounds were identified, mainly esters of fatty acids. The major components were the ethyl esters of palmitic acid (32.7%), linolenic acid (20.1%) and linoleic acid (10.5%).

Lycopene alleviates sulfamethoxazole-induced hepatotoxicity in grass carp (Ctenopharyngodon idellus) via suppression of oxidative stress, inflammation and apoptosis

2020 ◽  
Vol 11 (10) ◽  
pp. 8547-8559
Author(s):  
Hongjing Zhao ◽  
Yu Wang ◽  
Mengyao Mu ◽  
Menghao Guo ◽  
Hongxian Yu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Secondary Metabolites ◽  
Human Health ◽  
Grass Carp ◽  
Aquatic Environment ◽  
Ctenopharyngodon Idellus

Antibiotics are used worldwide to treat diseases in humans and other animals; most of them and their secondary metabolites are discharged into the aquatic environment, posing a serious threat to human health.

Conjugated Linoleic Acid Causes a Marked Increase in Liver α-Tocopherol and Liver α-Tocopherol Transfer Protein in C57BL/6 J Mice

2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw
Keyword(s):  
Antioxidant Enzymes ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Thiobarbituric Acid ◽  
Control Group ◽  
Thiobarbituric Acid Reactive Substances ◽  
Control Groups ◽  
Protein Levels ◽  
Transfer Protein ◽  
And Control

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.

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