scholarly journals Prevention of Melanin Formation by Yeast Cerebroside in B16 Mouse Melanoma Cells

2007 ◽  
Vol 56 (12) ◽  
pp. 645-648 ◽  
Author(s):  
Mikio Kinoshita ◽  
Naofumi Hori ◽  
Kazuhiko Aida ◽  
Tatsuya Sugawara ◽  
Masao Ohnishi
Keyword(s):  
Melanoma Cells ◽  
Mouse Melanoma ◽  
Melanin Formation ◽  
B16 Mouse Melanoma

scholarly journals Inhibition of Mushroom Tyrosinase and Melanogenesis B16 Mouse Melanoma Cells by Components Isolated from Curcuma longa

2008 ◽  
Vol 3 (10) ◽  
pp. 1934578X0800301 ◽  
Author(s):  
Jeong Ah Kim ◽  
Jong Keun Son ◽  
Hyun Wook Chang ◽  
Yurngdong Jahng ◽  
Youngsoo Kim ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Curcuma Longa ◽  
Melanoma Cells ◽  
Preparative Hplc ◽  
Mushroom Tyrosinase ◽  
Active Compounds ◽  
Mouse Melanoma ◽  
Melanin Formation ◽  
B16 Mouse Melanoma

The methanol extract of the rhizomes of Curcuma longa was found to inhibit tyrosinase activity. After partition, various column chromatographic and preparative HPLC procedures were used for bioassay guided isolation from the active ethyl acetate-soluble fraction. Various spectroscopic (1D-, 2D-NMR) and mass spectrometric techniques, and Mosher's esterification were applied to elucidate the structures of the isolated compounds. The isolates were tested using an in vitro mushroom tyrosinase assay. Inhibition of melanin formation by the active compounds was further evaluated using B16 mouse melanoma cells. Eleven compounds (1 – 11) were isolated from the rhizomes of C. longa by bioassay guided fractionation. The configuration at the C-4 position of 4-hydroxy-1,3(15),10-bisabolatrien-9-one (11) was confirmed by Mosher's method. Of the isolates, curcuminoids 5 - 7 showed potent inhibitory activity in the tyrosinase assay. Melanin formation of the active compounds in the B16 mouse melanoma cells corresponded with the tyrosinase inhibitory activity. The findings support the view that either curcuminoids or the extract of C. longa rhizomes containing them may be useful for the treatment of hyperpigmentation.

Methyl p-coumarate, a melanin formation inhibitor in B16 mouse melanoma cells

2004 ◽  
Vol 12 (20) ◽  
pp. 5349-5354 ◽  
Author(s):  
Isao Kubo ◽  
Ken-ichi Nihei ◽  
Kazuo Tsujimoto
Keyword(s):  
Melanoma Cells ◽  
Mouse Melanoma ◽  
Melanin Formation ◽  
B16 Mouse Melanoma

Non-malignant migration of B16 mouse melanoma cells in the neural crest and invasive growth in the eye cup of the chick embryo

2007 ◽  
Vol 17 (1) ◽  
pp. 17-30 ◽  
Author(s):  
Matthias Oppitz ◽  
Christian Busch ◽  
Gernot Schriek ◽  
Marco Metzger ◽  
Lothar Just ◽  
...  
Keyword(s):  
Chick Embryo ◽  
Neural Crest ◽  
Melanoma Cells ◽  
Invasive Growth ◽  
Mouse Melanoma ◽  
B16 Mouse Melanoma

scholarly journals Cycloalliin Inhibits Melanin Biosynthesis in B16 Mouse Melanoma Cells

2018 ◽  
Vol 24 (4) ◽  
pp. 627-633 ◽  
Author(s):  
Tomohiro Bito ◽  
Kyohei Koseki ◽  
Tomohiro Moriguchi ◽  
Yu Sasaki ◽  
Yukinori Yabuta ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
Melanin Biosynthesis ◽  
Mouse Melanoma ◽  
B16 Mouse Melanoma

Procyanidin Trimers to Pentamers Fractionated from Apple Inhibit Melanogenesis in B16 Mouse Melanoma Cells

2005 ◽  
Vol 53 (15) ◽  
pp. 6105-6111 ◽  
Author(s):  
Toshihiko Shoji ◽  
Saeko Masumoto ◽  
Nina Moriichi ◽  
Masuko Kobori ◽  
Tomomasa Kanda ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
Mouse Melanoma ◽  
B16 Mouse Melanoma
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