scholarly journals Fractionation of Conjugated Linoleic Acid Isomers by Selective Hydrolysis with Candida rugosa Lipase

2003 ◽  
Vol 52 (7) ◽  
pp. 367-374 ◽  
Author(s):  
Yoshie YAMAUCHI-SATO ◽  
Toshihiro NAGAO ◽  
Takaya YAMAMOTO ◽  
Tadamasa TERAI ◽  
Akio SUGIHARA ◽  
...  
2008 ◽  
Vol 106 (6) ◽  
pp. 559-562 ◽  
Author(s):  
Carlos F. Torres ◽  
Guzman Torrelo ◽  
Luis Vazquez ◽  
F. Javier Señorans ◽  
Guillermo Reglero

2012 ◽  
Vol 235 (1) ◽  
pp. 53-59 ◽  
Author(s):  
Laura Giua ◽  
Lina Cossignani ◽  
Maria Stella Simonetti ◽  
Germana Lombardi ◽  
Francesca Blasi

1998 ◽  
Vol 75 (11) ◽  
pp. 1581-1586 ◽  
Author(s):  
Yuji Shimada ◽  
Nobuhiro Fukushima ◽  
Hiroyuki Fujita ◽  
Yo Honda ◽  
Akio Sugihara ◽  
...  

2010 ◽  
Vol 80 (1) ◽  
pp. 65-73 ◽  
Author(s):  
Pei-Min Chao ◽  
Wan-Hsuan Chen ◽  
Chun-Huei Liao ◽  
Huey-Mei Shaw

Conjugated linoleic acid (CLA) is a collective term for the positional and geometric isomers of a conjugated diene of linoleic acid (C18:2, n-6). The aims of the present study were to evaluate whether levels of hepatic α-tocopherol, α-tocopherol transfer protein (α-TTP), and antioxidant enzymes in mice were affected by a CLA-supplemented diet. C57BL/6 J mice were divided into the CLA and control groups, which were fed, respectively, a 5 % fat diet with or without 1 g/100 g of CLA (1:1 mixture of cis-9, trans-11 and trans-10, cis-12) for four weeks. α-Tocopherol levels in plasma and liver were significantly higher in the CLA group than in the control group. Liver α-TTP levels were also significantly increased in the CLA group, the α-TTP/β-actin ratio being 2.5-fold higher than that in control mice (p<0.01). Thiobarbituric acid-reactive substances were significantly decreased in the CLA group (p<0.01). There were no significant differences between the two groups in levels of three antioxidant enzymes (superoxide dismutase, glutathione peroxidase, and catalase). The accumulation of liver α-tocopherol seen with the CLA diet can be attributed to the antioxidant potential of CLA and the ability of α-TTP induction. The lack of changes in antioxidant enzyme protein levels and the reduced lipid peroxidation in the liver of CLA mice are due to α-tocopherol accumulation.


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