scholarly journals Uzefulness of the Serum 1,3-dimethyluric acid/Theophylline Concentration Ratio in Patients Treated with Sustained-release Theophylline Preparations of Various Designs

2011 ◽  
Vol 37 (4) ◽  
pp. 261-267 ◽  
Author(s):  
Yuko Watanabe ◽  
Naohiko Chohnabayashi ◽  
Hideki Nasu ◽  
Naoki Nishimura ◽  
Noboru Uchiyama ◽  
...  
Keyword(s):  
Sustained Release ◽  
Concentration Ratio ◽  
Theophylline Concentration ◽  
Sustained Release Theophylline

Treatment of Chronic Obstructive Pulmonary Disease with Two Sustained-Release Theophylline Preparations

1987 ◽  
Vol 15 (6) ◽  
pp. 352-360
Author(s):  
S. Giosue' ◽  
D Bernocchi ◽  
D. Parola ◽  
R. Munno ◽  
P. Mancini
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Sustained Release ◽  
Slow Release ◽  
Chronic Obstructive ◽  
Theophylline Concentration ◽  
Obstructive Pulmonary Disease ◽  
Blood Samples ◽  
Theophylline Preparation ◽  
Plasma Theophylline ◽  
Sustained Release Theophylline

A sustained-release theophylline preparation in capsule form was compared with standard slow-release theophylline tablets for variation in plasma theophylline concentration, effectiveness and tolerability in 30 adults with chronic broncho-obstructive pathology. They were administered every 12 h and blood samples were collected after 8 days of treatment during the steady-state period. In this double-dummy crossover study, the sequence of the two regimens (sustained-release capsules versus tablets) was selected at random. The results of this study demonstrate that plasma theophylline levels remain within the therapeutic range for both preparations. Effectiveness and tolerability of the two drugs were satisfactory.

Problems in the Prescription of Sustained-Release Theophylline

1990 ◽  
Vol 4 (3) ◽  
pp. 207-215
Author(s):  
GEORGE B. MALLORY ◽  
MARITA Q. NAZARIAN ◽  
GREGORY D. KEARNS
Keyword(s):  
Sustained Release ◽  
Sustained Release Theophylline

Sustained-release theophylline: A significant advance in the treatment of childhood asthma

1982 ◽  
Vol 100 (3) ◽  
pp. 489-492 ◽  
Author(s):  
Elvan Tabachnik ◽  
Peter Scott ◽  
Junita Correia ◽  
Alan Isles ◽  
Stuart MacLeod ◽  
...  
Keyword(s):  
Sustained Release ◽  
Childhood Asthma ◽  
Significant Advance ◽  
Sustained Release Theophylline
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