scholarly journals Pulse-train Stimulation of Primary Somatosensory Cortex Blocks Pain Perception in Tail Clip Test

2017 ◽  
Vol 26 (2) ◽  
pp. 90-96 ◽  
Author(s):  
Soohyun Lee ◽  
Eunjin Hwang ◽  
Dongmyeong Lee ◽  
Jee Hyun Choi
Keyword(s):  
Somatosensory Cortex ◽  
Pulse Train ◽  
Pain Perception ◽  
Primary Somatosensory Cortex ◽  
Train Stimulation ◽  
Tail Clip ◽  
Stimulation Of

scholarly journals Cutaneous stimulation of the digits and lips evokes responses with different adaptation patterns in primary somatosensory cortex

NeuroImage ◽  
2010 ◽  
Vol 52 (4) ◽  
pp. 1477-1486 ◽  
Author(s):  
Mihai Popescu ◽  
Steven Barlow ◽  
Elena-Anda Popescu ◽  
Meredith E. Estep ◽  
Lalit Venkatesan ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Primary Somatosensory Cortex ◽  
Cutaneous Stimulation ◽  
Stimulation Of

Intrinsic discharge patterns and somatosensory inputs for neurons in raccoon primary somatosensory cortex

1994 ◽  
Vol 72 (6) ◽  
pp. 2827-2839 ◽  
Author(s):  
P. J. Istvan ◽  
P. Zarzecki
Keyword(s):  
Somatosensory Cortex ◽  
Cortical Neurons ◽  
Primary Somatosensory Cortex ◽  
Membrane Properties ◽  
Postsynaptic Potentials ◽  
Synaptic Inputs ◽  
Ionic Conductances ◽  
Discharge Patterns ◽  
Intrinsic Membrane Properties ◽  
Stimulation Of

1. Discharge patterns of neurons are regulated by synaptic inputs and by intrinsic membrane properties such as their complement of ionic conductances. Discharge patterns evoked by synaptic inputs are often used to identify the source and modality of sensory input. However, the interpretation of these discharge patterns may be complicated if different neurons respond to the same synaptic input with a variety of discharge patterns due to differences in intrinsic membrane properties. The purposes of this study were 1) to investigate intrinsic discharge patterns of neurons in primary somatosensory cortex of raccoon in vivo and 2) to use somatosensory postsynaptic potentials evoked by stimulation of forepaw digits to determine thalamocortical connectivity for the same neurons. 2. Conventional intracellular recordings with sharp electrodes were made from 121 neurons in the cortical representation of glabrous skin of digit four (d4). Intracellular injection of identical current pulses (100-120 ms in duration) elicited various patterns of discharge in different neurons. Neurons were classified on the basis of these intrinsic patterns of discharge, rates of spike adaptation, and characteristics of spike waveforms. Three main groups were identified: regular spiking (RS) neurons, intrinsic bursting (IB) neurons, and fast spiking (FS) neurons. Subclasses were identified for the RS and IB groups. 3. Neurons were tested for somatosensory inputs by stimulating electrically d3, d4, and d5. Excitatory postsynaptic potentials (EPSPs) were elicited in 100% of the neurons by electrical stimulation of d4, the "on-focus" digit. EPSPs were usually followed by inhibitory postsynaptic potentials (IPSPs). Many neurons (41%) responded with EPSP-IPSP sequences after stimulation of d3 or d5, the "off-focus" digits. 4. Latencies of somatosensory EPSPs and IPSPs were used to determine the synaptic order in the cortical circuitry of RS, IB, and FS neurons. EPSPs with monosynaptic thalamocortical latencies were recorded in RS, IB, and FS neurons. 5. We conclude that precise patterns of neural discharge in primary somatosensory cortex cannot be reliable estimates of sensory inputs reaching these neurons because patterns of discharge are so strongly influenced by intrinsic membrane properties. Ionic conductances governing patterns of neuronal discharge seem almost identical in intact cortex of raccoon, rat, and cat, and in slices of rodent cortex, because similar patterns of discharge are found. The consistency of patterns of discharge across species and types of preparation suggests that these intrinsic membrane properties are a general property of cerebral cortical neurons and should be considered when evaluation sensory coding by these neurons.

Effect of tactile interference stimulation of the ear in human primary somatosensory cortex: a magnetoencephalographic study

2003 ◽  
Vol 114 (10) ◽  
pp. 1866-1878 ◽  
Author(s):  
T Nihashi ◽  
R Kakigi ◽  
M Hoshiyama ◽  
K Miki ◽  
Y Kajita ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Primary Somatosensory Cortex ◽  
Stimulation Of

Stimulation of the somatosensory cortex using HD-tDCS modulates others' pain perception; Combined evidence from behaviour, EEG, fMRI data

2017 ◽  
Vol 10 (2) ◽  
pp. 466
Author(s):  
S. Gallo ◽  
T. Maskaljunas ◽  
B. Lammes ◽  
C. Henriques ◽  
J. Suttrup ◽  
...  
Keyword(s):  
Somatosensory Cortex ◽  
Pain Perception ◽  
Fmri Data ◽  
Stimulation Of

Differential Organization of Touch and Pain in Human Primary Somatosensory Cortex

2000 ◽  
Vol 83 (3) ◽  
pp. 1770-1776 ◽  
Author(s):  
Markus Ploner ◽  
Frank Schmitz ◽  
Hans-Joachim Freund ◽  
Alfons Schnitzler
Keyword(s):  
Somatosensory Cortex ◽  
Pain Perception ◽  
Hierarchical Organization ◽  
Primary Somatosensory Cortex ◽  
Nociceptive Response ◽  
Tactile Stimuli ◽  
Somatosensory Cortices ◽  
Cortical Responses ◽  
Nociceptive Processing ◽  
Nociceptive Afferents

Processing of tactile stimuli within somatosensory cortices has been shown to be complex and hierarchically organized. However, the precise organization of nociceptive processing within these cortices has remained largely unknown. We used whole-head magnetoencephalography to directly compare cortical responses to stimulation of tactile and nociceptive afferents of the dorsum of the hand in humans. Within the primary somatosensory cortex (SI), nociceptive stimuli activated a single source whereas tactile stimuli activated two sequentially peaking sources. Along the postcentral gyrus, the nociceptive SI source was located 10 mm more medially than the early tactile SI response arising from cytoarchitectonical area 3b and corresponded spatially to the later tactile SI response. Considering a mediolateral location difference between the hand representations of cytoarchitectonical areas 3b and 1, the present results suggest generation of the single nociceptive response in area 1, whereas tactile stimuli activate sequentially peaking sources in areas 3b and 1. Thus nociceptive processing apparently does not share the complex and hierarchical organization of tactile processing subserving elaborated sensory capacities. This difference in the organization of both modalities may reflect that pain perception rather requires reactions to and avoidance of harmful stimuli than sophisticated sensory capacities.

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