scholarly journals Erratum: Neuroprotective Effect of Lucium chinense Fruit on Trimethyltin-Induced Learning and Memory Deficits in the Rats

2011 ◽  
Vol 20 (4) ◽  
pp. 197-197
Author(s):  
Hyun-Jung Park ◽  
Hyun Soo Shim ◽  
Woong Ki Choi ◽  
Kyung Soo Kim ◽  
Hyunsu Bae ◽  
...  
Keyword(s):  
Learning And Memory ◽  
Neuroprotective Effect ◽  
Memory Deficits ◽  
Learning And Memory Deficits

scholarly journals Neuroprotective Effect of Lucium chinense Fruit on Trimethyltin-Induced Learning and Memory Deficits in the Rats

2011 ◽  
Vol 20 (3) ◽  
pp. 137-143 ◽  
Author(s):  
Hyun-Jung Park ◽  
Hyun Soo Shim ◽  
Woong Ki Choi ◽  
Kyung Soo Kim ◽  
Insop Shim
Keyword(s):  
Learning And Memory ◽  
Neuroprotective Effect ◽  
Memory Deficits ◽  
Learning And Memory Deficits

scholarly journals Neuroprotective Effect of Palmul-Chongmyeong-Tang on Ischemia-Induced Learning and Memory Deficits in the Rat

2007 ◽  
Vol 30 (2) ◽  
pp. 337-342 ◽  
Author(s):  
Young-Ju Yun ◽  
Bombi Lee ◽  
Dae-Hyun Hahm ◽  
Sung-Keel Kang ◽  
Seung-Moo Han ◽  
...  
Keyword(s):  
Learning And Memory ◽  
Neuroprotective Effect ◽  
Memory Deficits ◽  
Learning And Memory Deficits

scholarly journals Reversal of Trimethyltin-Induced Learning and Memory Deficits by 3,5-Dicaffeoylquinic Acid

2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Jin Yong Kang ◽  
Seon Kyeong Park ◽  
Tian Jiao Guo ◽  
Jeong Su Ha ◽  
Du Sang Lee ◽  
...  
Keyword(s):  
Learning And Memory ◽  
Neuroprotective Effect ◽  
Memory Deficits ◽  
Behavioral Tests ◽  
Dicaffeoylquinic Acid ◽  
Artemisia Argyi ◽  
Y Maze ◽  
Mda Content ◽  
Learning And Memory Deficits ◽  
Total Superoxide Dismutase

The antiamnesic effect of 3,5-dicaffeoylquinic acid (3,5-diCQA) as the main phenolic compound in Artemisia argyi H. extract on cognitive dysfunction induced by trimethyltin (TMT) (7.1 μg/kg of body weight; intraperitoneal injection) was investigated in order to assess its ameliorating function in mice. In several behavioral tests, namely, the Y-maze, passive avoidance, and Morris water maze (MWM) test, 3,5-diCQA significantly ameliorated learning and memory deficits. After the behavioral tests, brain tissues from the mice were analyzed to characterize the basis of the neuroprotective effect. Acetylcholine (ACh) levels increased, whereas the activity of acetylcholinesterase (AChE) decreased upon administration of 3,5-diCQA. In addition, 3,5-diCQA effectively protected against an increase in malondialdehyde (MDA) content, an increase in the oxidized glutathione (GSH) ratio, and a decline of total superoxide dismutase (SOD) level. 3,5-diCQA may prevent neuronal apoptosis through the protection of mitochondrial activities and the repression of apoptotic signaling molecules such as p-Akt, BAX, and p-tau (Ser 404).

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