scholarly journals The relationship of bone mineral density and vitamin D levels with steroid use and ambulation in patients with Duchenne muscular dystrophy

2019 ◽  
Vol 65 (3) ◽  
pp. 216-221
Author(s):  
Filiz Meryem Sertpoyraz
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Bone Mineral ◽  
Mineral Density ◽  
Steroid Use ◽  
Vitamin D Levels ◽  
Relationship Of ◽  
The Relationship

EFFECTS OF BISPHOSPHONATES ON OSTEOPOROSIS INDUCED BY DUCHENNE MUSCULAR DYSTROPHY: A PROSPECTIVE STUDY

2020 ◽  
Vol 26 (12) ◽  
pp. 1477-1485
Author(s):  
Wen-bin Zheng ◽  
Yi Dai ◽  
Jing Hu ◽  
Di-chen Zhao ◽  
Ou Wang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Alkaline Phosphatase ◽  
Duchenne Muscular Dystrophy ◽  
Zoledronic Acid ◽  
Muscular Dystrophy ◽  
Bone Mineral ◽  
Type I Collagen ◽  
Type I ◽  
Mineral Density

Objective: Duchenne muscular dystrophy (DMD) is a severe X-linked progressive neuromuscular disease that brings a significantly increased risk of osteoporosis and bone fractures. We prospectively evaluated the effects of oral and intravenous bisphosphonates on the bones of children with DMD. Methods: This study included a total of 52 children with DMD. They were divided into zoledronic acid (ZOL), alendronate (ALN), and control groups according to bone mineral density (BMD) and history of fragility fractures. For 2 years, all patients took calcium, vitamin D, and calcitriol. Meanwhile, 17 patients received infusions of ZOL, and 18 patients received ALN. BMD, serum levels of alkaline phosphatase (ALP) and the cross-linked C-telopeptide of type I collagen (β-CTX) were evaluated. Results: After 24 months of treatment, the percentage changes in lumbar spine BMD were 23.2 ± 9.7% and 23.6 ± 8.8% in the ZOL and ALN groups (all P<.01 vs. baseline). The increases did not differ between the ZOL and ALN groups, but were significantly larger than those of the control group ( P<.01). Serum β-CTX and ALP levels, respectively, were decreased by 44.4 ± 18.0% and 31.9 ± 26.7% in the ZOL group and by 36.0 ± 20.3% and 25.8 ± 14.4% in the ALN group (all P<.01 vs. baseline). Conclusion: Zoledronic acid and alendronate had similar protective effects to increase bone mineral density and reduce bone resorption in children with DMD, which were superior to treatment of calcium, vitamin D, and calcitriol. Abbreviations: 25OHD = 25 hydroxyvitamin D; ALN = alendro-nate; ALP = alkaline phosphatase; ALT = alanine aminotransferase; BMD = bone mineral density; BP = bisphosphonate; Ca = calcium; β-CTX = cross-linked C-telopeptide of type I collagen; DMD = Duchenne muscular dystrophy; FN = femoral neck; GC = glucocorticoid; LS = lumbar spine; ZOL = zoledronic acid

The relationship of vitamin D with bone mineral density in Parkinson's disease patients

2016 ◽  
Vol 7 (1) ◽  
pp. 18-22 ◽  
Author(s):  
M. Serdaroğlu Beyazal ◽  
S. Kırbaş ◽  
A. Tüfekçi ◽  
G. Devrimsel ◽  
A. Küçükali Türkyılmaz
Keyword(s):  
Bone Mineral Density ◽  
Parkinson’S Disease ◽  
Vitamin D ◽  
Parkinson's Disease ◽  
Bone Mineral ◽  
Mineral Density ◽  
Relationship Of ◽  
The Relationship

The relationship of vitamin D status to bone mineral density in an Italian population of postmenopausal women

2005 ◽  
Vol 16 (12) ◽  
pp. 1691-1697 ◽  
Author(s):  
Nazzarena Malavolta ◽  
Loredana Pratelli ◽  
Marilena Frigato ◽  
Rita Mulè ◽  
Maria Lucia Mascia ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Italian Population ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Relationship Of ◽  
The Relationship

scholarly journals The Relationship of Hand Grip Strength with Bone Mineral Density and Vitamin D in Postmenopausal Women

2016 ◽  
Vol 22 (1) ◽  
pp. 1-6
Author(s):  
Münevver Serdaroğlu Beyazal ◽  
Gül Devrimsel ◽  
Ayşegül Küçükali Türkyılmaz ◽  
Murat Yıldırım
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Grip Strength ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Hand Grip Strength ◽  
Mineral Density ◽  
Hand Grip ◽  
Relationship Of ◽  
The Relationship
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