scholarly journals Biperiden dependence and differential diagnosis with neuroleptic malignant syndrome: A case report

Author(s):  
Mehmet Hamdi Örüm
2021 ◽  
Vol 9 ◽  
pp. 232470962110297
Author(s):  
Ryan Serdenes ◽  
Samuel Orr ◽  
Pamela Trio ◽  
Seetha Chandrasekhara ◽  
Meghan Musselman

In this report, we describe a case of atypical neuroleptic malignant syndrome (NMS) presenting with an isolated lesion in the splenium of the corpus callosum (ILSCC). There is a paucity of information regarding this topic within the literature and only 7 previous case reports have been published at the time of writing. To our knowledge, this case report is also the first to describe an atypical NMS variant in the context of an ILSCC. In this report, we describe the important considerations in formulating differential diagnosis for ILSCC and are the first report to propose a possible pathophysiological mechanism relating ILSCC with NMS.


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