scholarly journals Diagnostic difficulties in neuroendocrine tumors — intrapancreatic accessory spleen

2017 ◽  
Vol 20 (2) ◽  
pp. 103-104
Author(s):  
Anna Skowrońska ◽  
Tomasz Bednarczuk ◽  
Joanna Podgórska ◽  
Dorota Kaczmarska-Turek ◽  
Jarosław Ćwikła
2016 ◽  
Vol 22 (7) ◽  
pp. 773-779 ◽  
Author(s):  
Ester Osher ◽  
Erez Scapa ◽  
Joseph Klausner ◽  
Yona Greenman ◽  
Karen Tordjman ◽  
...  

2016 ◽  
pp. 15 ◽  
Author(s):  
Marco Massani ◽  
Paola Maccatrozzo ◽  
Giovanni Morana ◽  
Luca Fabris ◽  
Cesare Ruffolo ◽  
...  

Author(s):  
Milan Radojkovic ◽  
Danijela Radojkovic ◽  
Natalija Premovic

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Virginia Liberini ◽  
Fotis Kotasidis ◽  
Valerie Treyer ◽  
Michael Messerli ◽  
Erika Orita ◽  
...  

AbstractTo evaluate whether quantitative PET parameters of motion-corrected 68Ga-DOTATATE PET/CT can differentiate between intrapancreatic accessory spleens (IPAS) and pancreatic neuroendocrine tumor (pNET). A total of 498 consecutive patients with neuroendocrine tumors (NET) who underwent 68Ga-DOTATATE PET/CT between March 2017 and July 2019 were retrospectively analyzed. Subjects with accessory spleens (n = 43, thereof 7 IPAS) and pNET (n = 9) were included, resulting in a total of 45 scans. PET images were reconstructed using ordered-subsets expectation maximization (OSEM) and a fully convergent iterative image reconstruction algorithm with β-values of 1000 (BSREM1000). A data-driven gating (DDG) technique (MOTIONFREE, GE Healthcare) was applied to extract respiratory triggers and use them for PET motion correction within both reconstructions. PET parameters among different samples were compared using non-parametric tests. Receiver operating characteristics (ROC) analyzed the ability of PET parameters to differentiate IPAS and pNETs. SUVmax was able to distinguish pNET from accessory spleens and IPAs in BSREM1000 reconstructions (p < 0.05). This result was more reliable using DDG-based motion correction (p < 0.003) and was achieved in both OSEM and BSREM1000 reconstructions. For differentiating accessory spleens and pNETs with specificity 100%, the ROC analysis yielded an AUC of 0.742 (sensitivity 56%)/0.765 (sensitivity 56%)/0.846 (sensitivity 62%)/0.840 (sensitivity 63%) for SUVmax 36.7/41.9/36.9/41.7 in OSEM/BSREM1000/OSEM + DDG/BSREM1000 + DDG, respectively. BSREM1000 + DDG can accurately differentiate pNET from accessory spleen. Both BSREM1000 and DDG lead to a significant SUV increase compared to OSEM and non-motion-corrected data.


2015 ◽  
Vol 40 (9) ◽  
pp. 744-745 ◽  
Author(s):  
Ujwal Bhure ◽  
Jürg Metzger ◽  
Franziska Aebersold Keller ◽  
Andrea Zander ◽  
Marisol Pérez Lago ◽  
...  

2011 ◽  
Vol 2 (6) ◽  
pp. 128-130 ◽  
Author(s):  
Niroshan Sothilingam ◽  
Toni Leedahl ◽  
Stefan Kriegler ◽  
Rani Kanthan ◽  
Michael A.J. Moser

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Willemijn P. M. van Dijck ◽  
Vincent P. Groot ◽  
Lodewijk A. A. Brosens ◽  
Jeroen Hagendoorn ◽  
Inne H. M. Borel Rinkes ◽  
...  

Epithelial cyst in an intrapancreatic accessory spleen (ECIPAS) is exceedingly rare with only 57 cases reported since the first publication in 1980. Comprehensive clinical and diagnostic features remain to be clarified. We present a case of ECIPAS in a 21-year-old Philippine woman who was admitted with right upper quadrant abdominal pain. A cystic lesion in the pancreatic tail was discovered and evaluated by computed tomography and magnetic resonance images. Based on clinical and radiological features a solid pseudopapillary neoplasm was suspected. The patient underwent robot-assisted spleen preserving distal pancreatectomy. Pathological evaluation revealed a 26 mm intrapancreatic accessory spleen with a 16 mm cyst, lined by multilayered epithelium in the tail of the pancreas. The postoperative course was uneventful. Differentiating ECIPAS from (pre)malignant cystic pancreatic neoplasms based on clinical and radiological features remains difficult. When typical radiological signs can be combined with scintigraphy using Technetium-99m labelled colloid or Technetium-99m labelled erythrocytes, which can identify the solid component of the lesion as splenic tissue, it should be possible to make the right diagnosis noninvasively. When pancreatectomy is inevitable due to symptoms or patient preference, minimally invasive laparoscopic or robot-assisted spleen preserving distal pancreatectomy should be considered.


Pancreatology ◽  
2019 ◽  
Vol 19 (1) ◽  
pp. 10-16 ◽  
Author(s):  
Bing-Qi Li ◽  
Jun Lu ◽  
Samuel Seery ◽  
Jun-Chao Guo

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Tomokatsu Kato ◽  
Yoichi Matsuo ◽  
Goro Ueda ◽  
Yoshinaga Aoyama ◽  
Kan Omi ◽  
...  

Abstract Background An epithelial cyst in an intrapancreatic accessory spleen (ECIPAS) is rare. We report a case of ECIPAS that was treated with robot-assisted distal pancreatectomy with splenectomy. Case presentation The case was a 59-year-old woman who was referred to our hospital after a pancreatic tail tumor was found on computed tomography prior to surgery for small bowel obstruction at another hospital. A cystic lesion in the pancreatic tail was discovered and evaluated by magnetic resonance imaging and endoscopic ultrasonography. Based on clinical and radiological features, mucinous cystic neoplasm was included in the differential diagnosis. The patient underwent robot-assisted distal pancreatectomy with splenectomy. The postoperative course was uneventful. Pathological evaluation revealed a 20-mm ECIPAS in the pancreatic tail. Conclusions If a pancreatic tail tumor is present, ECIPAS should be included in the differential diagnosis. However, preoperative diagnosis is difficult, and a definitive diagnosis is often not obtained until after surgery. Surgery should be minimally invasive. Laparoscopic distal pancreatectomy has become a standard surgical procedure because it is minimally invasive. Robot-assisted surgery is not only minimally invasive, but also advantageous, because it has a stereoscopic magnifying effect and allows the forceps to move smoothly. Robot-assisted distal pancreatectomy may be a good option, when performing surgery for a pancreatic tail tumor.


2018 ◽  
Vol 80 (4) ◽  
pp. 701-705 ◽  
Author(s):  
Shotaro NAKAGUN ◽  
Josué DÍAZ-DELGADO ◽  
Kátia R. GROCH ◽  
Yoshiyasu KOBAYASHI

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