The association between serum serglycin level and coronary artery disease severity in patients with stable angina pectoris

2018 ◽  
pp. 783-790 ◽  
Author(s):  
Hasan Ata Bolayır ◽  
Tarık Kıvrak ◽  
Hakan Gunes ◽  
Aslı Bolayır ◽  
Ilgın Karaca
Angiology ◽  
2021 ◽  
pp. 000331972199885
Author(s):  
Omer Faruk Cirakoglu ◽  
Ayşe Gül Karadeniz ◽  
Ali Riza Akyüz ◽  
Cihan Aydın ◽  
Sinan Şahin ◽  
...  

Accurately identifying coronary artery disease (CAD) is the key element in guiding the work-up of patients with suspected angina. Thickening of the arterial wall is a hallmark of atherosclerosis. Therefore, the main purpose of this study was to determine whether abdominal aortic intima-media thickness (AAIMT), which is the earliest zone of atherosclerotic manifestations, has a predictive value in CAD severity. A total of 255 consecutive patients who were referred for invasive coronary angiography due to suspected stable angina pectoris were prospectively included in the study. B-mode ultrasonography was used to determine AAIMT before coronary angiography. Coronary artery disease severity was assessed with the SYNTAX score (SS). A history of hypertension, age, dyslipidemia, and higher AAIMT (odds ratio: 2.570; 95%CI 1.831-3.608; P < .001) were independent predictors of intermediate or high SS. An AAIMT <1.3 mm had a negative predictive value of 98% for the presence of intermediate or high SS and 83% for obstructive CAD. In conclusion, AAIMT showed a significant and independent predictive value for intermediate or high SS. Therefore, AAIMT may be a noninvasive and useful tool for decision-making by cardiologists (eg, to use a more invasive approach).


Circulation ◽  
1987 ◽  
Vol 76 (1) ◽  
pp. 15-20 ◽  
Author(s):  
C Rainer ◽  
D T Kawanishi ◽  
P A Chandraratna ◽  
R M Bauersachs ◽  
C L Reid ◽  
...  

2020 ◽  
Author(s):  
Mustafa Duran ◽  
Deniz Elcik ◽  
Mehmet T Inanc ◽  
Mikail Yarlıoglues ◽  
Ibrahim E Celik ◽  
...  

Aim: We investigated the relationship between mild renal dysfunction (MRD) and the presence of coronary artery disease (CAD) in people under 60. Materials & methods: A total of 634 (317 patients with vessel stenosis ≥50% and 317 with normal angiography) individuals diagnosed with stable angina pectoris and estimated glomerular filtration rate (eGFR) ≥60 ml/min/1.73 m2 were included in the present study. Results: The mean eGFR was lower (95.3 ± 23.7 vs 109.7 ± 22.3, respectively, p = 0.002) and the number of patients with MRD was higher in patients with CAD (137, 43.2%) than in the control group (52, 16.4%, p < 0.001). The multivariate analysis showed that lower eGFR is an independent risk factor for presence of CAD in people under 60 with stable angina pectoris. Conclusion: According to our retrospective study, the risk of developing CAD appears to be slightly increased in individuals under 60 with MRD.


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