Hybrid approach for acute limb ischaemia after transcatheter aortic valve implantation

2015 ◽  
pp. 378-378
Author(s):  
Michał Ł. Lelek ◽  
Grzegorz Smolka ◽  
Michał Krejca ◽  
Andrzej Ochała ◽  
Katarzyna Mizia-Stec
Keyword(s):  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Hybrid Approach ◽  
Limb Ischaemia ◽  
Transcatheter Aortic Valve ◽  
Acute Limb Ischaemia ◽  
Aortic Valve Implantation ◽  
Valve Implantation

scholarly journals Major threats to early safety after transcatheter aortic valve implantation in a contemporary cohort of real-world patients

2021 ◽  
Author(s):  
D. J. van Ginkel ◽  
J. Brouwer ◽  
N. D. van Hemert ◽  
A. O. Kraaijeveld ◽  
B. J. W. M. Rensing ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Aortic Valve ◽  
Transcatheter Aortic Valve Implantation ◽  
Major Bleeding ◽  
Real World ◽  
Pacemaker Implantation ◽  
Limb Ischaemia ◽  
Transcatheter Aortic Valve ◽  
Aortic Valve Implantation ◽  
Valve Implantation

Abstract Introduction Despite considerable advances in the last decade, major adverse events remain a concern after transcatheter aortic valve implantation (TAVI). The aim of this study was to provide a detailed overview of their underlying causes and contributing factors in order to identify key domains for quality improvement. Methods This observational, prospective registry included all patients undergoing TAVI between 31 December 2015 and 1 January 2020 at the St. Antonius Hospital in Nieuwegein and the University Medical Centre in Utrecht. Outcomes of interest were all-cause mortality, stroke, major bleeding, life-threatening or disabling bleeding, major vascular complications, myocardial infarction, severe acute kidney injury and conduction disturbances requiring permanent pacemaker implantation within 30 days after TAVI, according to the Valve Academic Research Consortium‑2 criteria. Results Of the 1250 patients who underwent TAVI in the evaluated period, 146 (11.7%) developed a major complication. In 54 (4.3%) patients a thromboembolic event occurred, leading to stroke in 36 (2.9%), myocardial infarction in 13 (1.0%) and lower limb ischaemia in 11 (0.9%). Major bleeding occurred in 65 (5.2%) patients, most frequently consisting of acute cardiac tamponade (n = 25; 2.0%) and major access-site bleeding (n = 21; 1.7%). Most complications occurred within 1 day of the procedure. Within 30 days a total of 54 (4.3%) patients died, the cause being directly TAVI-related in 30 (2.4%). Of the patients who died from causes that were not directly TAVI-related, 14 (1.1%) had multiple hospital-acquired complications. Conclusion A variety of underlying mechanisms and causes form a wide spectrum of major threats affecting early safety in 11.7% of patients undergoing TAVI in a contemporary cohort of real-world patients.

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