scholarly journals Comparison of Anti-müllerian Hormone (AMH) and Hormonal Assays for Phenotypic Classification of Polycystic Ovary Syndrome

2020 ◽  
Vol 91 (11) ◽  
pp. 661-667
Author(s):  
Ali Cenk Ozay ◽  
Ozlen Emekcı Ozay ◽  
Bulent Gulekli
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Phenotypic Classification

scholarly journals Use of the serum anti-Müllerian hormone assay as a surrogate for polycystic ovarian morphology: impact on diagnosis and phenotypic classification of polycystic ovary syndrome

2017 ◽  
Vol 32 (8) ◽  
pp. 1716-1722 ◽  
Author(s):  
Alice Fraissinet ◽  
Geoffroy Robin ◽  
Pascal Pigny ◽  
Tiphaine Lefebvre ◽  
Sophie Catteau-Jonard ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Ovarian Morphology ◽  
Hormone Assay ◽  
Phenotypic Classification

Classification of polycystic ovary syndrome into three types according to response to human corticotropin-releasing hormone

1999 ◽  
Vol 72 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Yoshihito Kondoh ◽  
Tsuguo Uemura ◽  
Masahiko Ishikawa ◽  
Natsuko Yokoi ◽  
Fumiki Hirahara
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Corticotropin Releasing Hormone ◽  
Ovary Syndrome ◽  
Releasing Hormone

scholarly journals Data mining polycystic ovary morphology in electronic medical record ultrasound reports

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Jay Jojo Cheng ◽  
Shruthi Mahalingaiah
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Large Scale ◽  
Polycystic Ovary ◽  
Medical Center ◽  
Ultrasound Images ◽  
Dominant Follicle ◽  
Ovary Syndrome ◽  
Test Set ◽  
Report Text

Abstract Background Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenemia, oligo-anovulation, and numerous ovarian cysts. Hospital electronic medical records provide an avenue for investigating polycystic ovary morphology commonly seen in PCOS at a large scale. The purpose of this study was to develop and evaluate the performance of two machine learning text algorithms, for classification of polycystic ovary morphology (PCOM) in pelvic ultrasounds. Methods Pelvic ultrasound reports from patients at Boston Medical Center between October 1, 2003 and December 12, 2016 were included for analysis, which resulted in 39,093 ultrasound reports from 25,535 unique women. Following the 2003 Rotterdam Consensus Criteria for polycystic ovary syndrome, 2000 randomly selected ultrasounds were expert labeled for PCOM status as present, absent, or unidentifiable (not able to be determined from text alone). An ovary was marked as having PCOM if there was mention of numerous peripheral follicles or if the volume was greater than 10 ml in the absence of a dominant follicle or other confounding pathology. Half of the labeled data was used to develop and refine the algorithms, and the other half was used as a test set for evaluating its accuracy. Results On the evaluation set of 1000 random US reports, the accuracy of the classifiers were 97.6% (95% CI: 96.5, 98.5%) and 96.1% (94.7, 97.2%). Both models were more adept at identifying PCOM-absent ultrasounds than either PCOM-unidentifiable or PCOM-present ultrasounds. The two classifiers estimated prevalence of PCOM within the whole set of 39,093 ultrasounds to be 44% PCOM-absent, 32% PCOM-unidentifiable, and 24% PCOM-present. Conclusions Although accuracy measured on the test set and inter-rater agreement between the two classifiers (Cohen’s Kappa = 0.988) was high, a major limitation of our approach is that it uses the ultrasound report text as a proxy and does not directly count follicles from the ultrasound images themselves.

Sign in / Sign up

Export Citation Format

Share Document