scholarly journals Relationship between maternal blood ceruloplasmin level, catalase and myeloperoxidase activity and neural tube defects

2017 ◽  
Vol 88 (3) ◽  
pp. 156-160 ◽  
Author(s):  
Orkun Cetin ◽  
Erbil Karaman ◽  
Baris Boza ◽  
Numan Cim ◽  
Murat Alisik ◽  
...  
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Maternal Blood ◽  
Myeloperoxidase Activity ◽  
Ceruloplasmin Level

scholarly journals Infl uence of selenium deficiency on neural tube defects

2014 ◽  
Vol 6 (2) ◽  
pp. 62-65
Author(s):  
Rajeev Vats
Keyword(s):  
Blood Serum ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Venous Blood ◽  
Cell Mass ◽  
Selenium Deficiency ◽  
Prenatal Development ◽  
Maternal Blood ◽  
Selenium Status ◽  
Medical Sciences

Objective: As for the role of selenium on human fetal development, a little data is available in literature.  The purpose of this manuscript was to study the influence of selenium on neural tube defects. This study will be helpful in planning strategies for prevention of neural   tube defects.Methodology: After collection of the venous blood the same was immediately centrifuged and after immediate centrifugation, the clear serum was transferred to deionized plastic vials, stored and frozen at –20º C until determination of the analysis was carried out. The selenium levels as ng/ml were determined on GBC 932 spectrophotometer by fluorometery.Results: The mean maternal blood serum and cell mass concentrations in NTD group (306.4 ± 10.95 ng/ml, 192.44 ± 6.12 ng/ml, 165.8 ± 16.99 ng/g respectively) were significantly lower than those of control mothers (363.75 ± 17.1 ng/ml, 242.34 ± 15.7 ng/ml, 260.0 ± 20.57 respectively).  A significant decrease in concentration of selenium in newborns with NTD (298.4 ± 12.3 ng/ml, 96.3 ± 7.15 ng/ml, 139.8 ± 27.5 ng/g respectively) as compared with healthy babies (358.1 ± 16.11 ng/ml, 122.44 ± 6.03 ng/ml, 268.6 ± 31.37 ng/g respectively).Conclusion: Selenium deficiency in mothers during pregnancy thought to be one of the factors responsible for NTDs.  However, the lowered selenium concentrations in blood, serum and cell mass can be secondary cause of an abnormal pregnancy and didn’t contribute to its production.  More investigations on selenium status in mothers during antenatal period, especially in prenatal development and antenatal selenium status including normal babies and NTD babies are required.DOI: http://dx.doi.org/10.3126/ajms.v6i2.11151Asian Journal of Medical Sciences Vol.6(2) 2015 62-65    

Lessons from dolutegravir and neural tube defects

2021 ◽  
Vol 8 (1) ◽  
pp. e3-e4
Author(s):  
Elaine Abrams ◽  
Landon Myer
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects

A Public Health Success Story: Folic Acid Fortification and Supplementation for Prevention of Neural Tube Defects

2004 ◽  
Author(s):  
Linda Longerich ◽  
Roy West ◽  
Ed Randell ◽  
Marian Crowley ◽  
Shiliang Liu ◽  
...  
Keyword(s):  
Public Health ◽  
Folic Acid ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Success Story ◽  
Folic Acid Fortification

Detection of spina bifida in the first trimester of gestation in association with triploidy

2017 ◽  
Author(s):  
K.K. Otaryan , C.G. Gagaev
Keyword(s):  
Spina Bifida ◽  
Early Detection ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
First Trimester ◽  
Termination Of Pregnancy ◽  
Diagnostic Tools ◽  
Prenatal Detection ◽  
Post Abortion

The case of prenatal detection of spina bifida at 12+3 weeks of gestation is described. Termination of pregnancy was performed at 13+3 weeks. Post-abortion karyotyping revealed triploidy (69XXX). Diagnostic tools for early detection of neural tube defects in the 1st trimester of gestation and subsequent appropriate management of pregnancy are discussed.

Neural tube defects: prenatal screening.

1996 ◽  
Vol 166 (2) ◽  
pp. 466-467 ◽  
Author(s):  
G K Sickler ◽  
D A Nyberg
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Prenatal Screening

scholarly journals Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects

Cell Reports ◽  
2019 ◽  
Vol 27 (2) ◽  
pp. 442-454.e5 ◽  
Author(s):  
Alex R.D. Delbridge ◽  
Andrew J. Kueh ◽  
Francine Ke ◽  
Natasha M. Zamudio ◽  
Farrah El-Saafin ◽  
...  
Keyword(s):  
X Chromosome ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
X Chromosome Inactivation ◽  
Chromosome Inactivation ◽  
Female Specific
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