scholarly journals The role of immunohistochemical examination in diagnosis of papillary thyroid cancer in struma ovarii

2015 ◽  
Author(s):  
Ewelina Szczepanek-Parulska ◽  
Anna Pioch ◽  
Ewa Cyrańska-Chyrek ◽  
Kosma Wolinski ◽  
Donata Jarmołowska-Jurczyszyn ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Struma Ovarii ◽  
Papillary Thyroid ◽  
Immunohistochemical Examination

The Role of Different Molecular Markers in Papillary Thyroid Cancer Patients with Acromegaly

2018 ◽  
Vol 127 (07) ◽  
pp. 437-444 ◽  
Author(s):  
Fatma Ela Keskin ◽  
Hande Mefkure Ozkaya ◽  
Sina Ferahman ◽  
Ozlem Haliloglu ◽  
Adem Karatas ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Ex Vivo ◽  
Papillary Thyroid ◽  
Cerrahpasa Medical Faculty ◽  
Protein Expressions ◽  
Galectin 3 ◽  
Benign Nodules ◽  
Igf1 Expression

Abstract Purpose Prevalence of papillary thyroid cancer (PTC) is increased in patients with acromegaly. We aimed to determine the protein expression of BRAF, RAS, RET, insulin like growth factor 1(IGF1), Galectine 3, CD56 in patients with PTC related acromegaly and to compare the extensity of these expressions with normal PTC patients and benign thyroid nodules. Methods We studied 313 patients with acromegaly followed in Cerrahpasa Medical Faculty, Endocrinology and Metabolism Clinic between 1998 and 2015. On the basis of availability of pathological specimen of thyroid tissues, thyroid samples of 13 patients from 19 with acromegaly related PTC (APTC), 20 normal PTC and 20 patients with multinodulary goiter (MNG) were histopathologically evaluated. Protein expressions were determined via immunohistochemical staining in ex-vivo tumor samples and benign nodules. Results The incidence of PTC in acromegaly patients were 6% (n=19). Among patients with PTC, APTC and MNG, all the immunohistochemical protein expressions we have studied were higher in papillary thyroid cancer groups (p<0.01, for all). Between PTC group without acromegaly and APTC, galectin 3 and IGF1 expression was significantly higher in acromegalic patients (p<0.01 for all) while RAS was predominantly higher in PTC patients without acromegaly (p<0.01). Conclusion BRAF expression was not higher in PTC with acromegaly patients compared to PTC patients without acromegaly. Galectine 3 and IGF1 were expressed more intensively in APTC. These positive protein expressions may have more influence on determining malign nodules among acromegaly patients.

scholarly journals The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family

2016 ◽  
Vol 17 (6) ◽  
pp. 909 ◽  
Author(s):  
Ewelina Perdas ◽  
Robert Stawski ◽  
Dariusz Nowak ◽  
Maria Zubrzycka
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid

Role of Prophylactic Thyroid Neck Dissection in Papillary Thyroid Cancer

2017 ◽  
Vol 69 (6) ◽  
pp. 2694-2697
Author(s):  
Hisham Sameer Alhathloul ◽  
Mohammed Ahmed Almasabi ◽  
Abdulghani Mohammad Lodhi
Keyword(s):  
Thyroid Cancer ◽  
Neck Dissection ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid

Malignant struma ovarii with a focus of papillary thyroid cancer: a case report

2007 ◽  
Vol 277 (4) ◽  
pp. 371-373 ◽  
Author(s):  
Melike Doganay ◽  
Tayfun Gungor ◽  
Sabri Cavkaytar ◽  
Levent Sirvan ◽  
Leyla Mollamahmutoglu
Keyword(s):  
Thyroid Cancer ◽  
Case Report ◽  
Papillary Thyroid Cancer ◽  
Struma Ovarii ◽  
Papillary Thyroid ◽  
Malignant Struma Ovarii

Role of P53, E-cadherin and BRAF as predictors of regional nodal recurrence for papillary thyroid cancer

2019 ◽  
Vol 40 ◽  
pp. 59-65 ◽  
Author(s):  
Khadiga M. Ali ◽  
Shadi Awny ◽  
Dina Abdallah Ibrahim ◽  
Islam H. Metwally ◽  
Omar Hamdy ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Papillary Thyroid ◽  
Nodal Recurrence ◽  
Regional Nodal Recurrence ◽  
E Cadherin
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