scholarly journals A comparative study evaluating C-reactive protein, sputum eosinophils and forced expiratory volume in one second in obese and nonobese asthmatics

2020 ◽  
Vol 88 (5) ◽  
pp. 394-399
Author(s):  
Harish Mahender ◽  
Raja Amarnath ◽  
Sreenivasan Vadivelu
Keyword(s):  
Comparative Study ◽  
Forced Expiratory Volume ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Sputum Eosinophils

Cross-sectional and longitudinal associations between urinary zinc and lung function among urban adults in China

Thorax ◽  
2020 ◽  
Vol 75 (9) ◽  
pp. 771-779 ◽  
Author(s):  
Min Zhou ◽  
Lili Xiao ◽  
Shijie Yang ◽  
Bin Wang ◽  
Tingming Shi ◽  
...  
Keyword(s):  
Lung Function ◽  
Oxidative Damage ◽  
Systemic Inflammation ◽  
Secretory Protein ◽  
Forced Expiratory Volume ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Mediation Analyses ◽  
Reactive Protein

BackgroundExposure to zinc was suggested to be associated with pulmonary damage, but whether zinc exposure affects lung function remains unclear.ObjectivesTo quantify the association between urinary zinc and lung function and explore the potential mechanisms.MethodsUrinary zinc and lung function were measured in 3917 adults from the Wuhan-Zhuhai cohort and were repeated after 3 years of follow-up. Indicators of systemic inflammation (C reactive protein), lung epithelium integrity (club cell secretory protein-16) and oxidative damage (8-hydroxy-2′-deoxyguanosine and 8-isoprostane) were measured at baseline. Linear mixed models were used to estimate the exposure–response relationship between urinary zinc and lung function. Mediation analyses were conducted to assess mediating roles of inflammation and oxidative damage in above relationships.ResultsEach 1-unit increase in log-transformed urinary zinc values was associated with a 35.72 mL decrease in forced vital capacity (FVC) and a 24.89 mL decrease in forced expiratory volume in 1 s (FEV1) in the baseline analyses. In the follow-up analyses, there was a negative association between urinary zinc and FVC among participants with persistent high urinary zinc levels, with an estimated change of −93.31 mL (95% CI −178.47 to −8.14). Furthermore, urinary zinc was positively associated with restrictive ventilatory impairment. The mediation analyses suggested that C reactive protein mediated 8.62% and 8.71% of the associations of urinary zinc with FVC and FEV1, respectively.ConclusionUrinary zinc was negatively associated with lung function, and the systemic inflammation may be one of the underlying mechanisms.

A comparative study of optical techniques applied to particle-enhanced assays of C-reactive protein

1997 ◽  
Vol 205 (2) ◽  
pp. 151-156 ◽  
Author(s):  
J.L Ortega-Vinuesa ◽  
J.A Molina-Bolı́var ◽  
J.M Peula ◽  
R Hidalgo-Álvarez
Keyword(s):  
Comparative Study ◽  
C Reactive Protein ◽  
Optical Techniques ◽  
Reactive Protein

scholarly journals Comparative Study of C-Reactive Protein in Chronic Hepatiti B and Chronic Hepatitis C.

1996 ◽  
Vol 178 (3) ◽  
pp. 287-297 ◽  
Author(s):  
Masayoshi Shima ◽  
Kazuhiko Nakao ◽  
Yuji Kato ◽  
Keisuke Nakata ◽  
Nobuko Ishii ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Comparative Study ◽  
Chronic Hepatitis C ◽  
C Reactive Protein ◽  
Reactive Protein

scholarly journals CO-RADS versus CT-SS scores in predicting severe COVID-19 patients: retrospective comparative study

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Niveen E. Zayed ◽  
Manar A. Bessar ◽  
Samah Lutfy
Keyword(s):  
Comparative Study ◽  
Severe Disease ◽  
Scoring Systems ◽  
Rt Pcr ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Polymerase Chain ◽  
Retrospective Comparative Study ◽  
Rule Out

Abstract Background The role of CT in assessing and plotting viral pulmonary affection land marking is its potential among other investigation tools, and the aim of the study was to compare the ability of two different CT-based scoring systems in discriminating severe COVID-19 disease. Results Retrospective comparative study included 142 confirmed COVID-19 patients by real-time polymerase chain reaction (RT-PCR) test, with different degrees of disease (mild to severe), the data of patients collected from medical records, and patients with their first CT chest read for calculating CO-RADS and severity scoring system (CT-SS) score. The patients with severe COVID-19 disease were significantly older and had different comorbidities. The level of C-reactive protein, ESR, ferritin, and LDH were significantly higher in severe disease, P < 0.001. The ability of CT chest and its score bases (CT-SS and CO-RADS) were accurate in differentiation between mild/moderate and severe disease; AUC were 89% and 97%, respectively. The cutoff value of less than 7.5 and 4.5 for CT-SS and CO-RADS, respectively, can rule out severe COVID-19 by 90% and 97%, respectively. Conclusions CT chest play a segregate role in COVID-19 disease, add on an advantage in clinical data in triage, and highlight the decision of hospital admission.

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