scholarly journals Diagnostic implications of bronchial lavage in patients with pleural tuberculosis

2020 ◽  
Vol 88 (5) ◽  
pp. 389-393
Author(s):  
Kamran Khan Sumalani ◽  
Nousheen Akhter ◽  
Maqbool Ahmed ◽  
Dimple Chawla ◽  
Nadeem Ahmed Rizvi
Keyword(s):  
Bronchial Lavage ◽  
Pleural Tuberculosis

Pleural fluid tumor necrosis factor for diagnosis of pleural tuberculosis: A systematic review and meta-analysis

Cytokine ◽  
2021 ◽  
Vol 141 ◽  
pp. 155467
Author(s):  
Ashutosh Nath Aggarwal ◽  
Ritesh Agarwal ◽  
Sahajal Dhooria ◽  
Kuruswamy Thurai Prasad ◽  
Inderpaul Singh Sehgal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Tumor Necrosis Factor ◽  
Pleural Fluid ◽  
Tumor Necrosis ◽  
Meta Analysis ◽  
Pleural Tuberculosis ◽  
Necrosis Factor

Extensive fibrosis caused by Pleural Tuberculosis: A lesson from a case without post-exposure-prophylaxis

2012 ◽  
Vol 48 (2) ◽  
pp. 206-209
Author(s):  
Julius Valentin Emmrich ◽  
Manja Kamprad ◽  
Ina Sorge ◽  
Stefan Hammerschmidt ◽  
Tanja Gradistanac ◽  
...  
Keyword(s):  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Pleural Tuberculosis ◽  
Exposure Prophylaxis

Diagnosis of Pleural Tuberculosis

CHEST Journal ◽  
2002 ◽  
Vol 121 (3) ◽  
pp. 1005 ◽  
Author(s):  
David Jiménez ◽  
Gema Díaz ◽  
Esteban Pérez-Rodríguez
Keyword(s):  
Pleural Tuberculosis

scholarly journals P5 Pleural tuberculosis in london: a persistent diagnostic challenge

2017 ◽  
Author(s):  
L Peters ◽  
GK Russell ◽  
LJ Martin ◽  
LY Han ◽  
M O’Donoghue ◽  
...  
Keyword(s):  
Diagnostic Challenge ◽  
Pleural Tuberculosis

Microbiological lung surveillance in mechanically ventilated patients, using non-directed bronchial lavage and quantitative culture

QJM ◽  
1993 ◽  
Vol 86 (10) ◽  
pp. 635-648 ◽  
Author(s):  
C.H.D. A'court ◽  
C.S. Garrard ◽  
D. Crook ◽  
I. Bowler ◽  
C. Conlon ◽  
...  
Keyword(s):  
Quantitative Culture ◽  
Mechanically Ventilated ◽  
Mechanically Ventilated Patients ◽  
Bronchial Lavage ◽  
Ventilated Patients

scholarly journals Epidemiology and diagnosis of pleural tuberculosis in a low incidence country with high rate of immigrant population: A retrospective study

2019 ◽  
Vol 78 ◽  
pp. 34-38
Author(s):  
Antonio Macías ◽  
Adrián Sánchez-Montalvá ◽  
Fernando Salvador ◽  
Ana Villar ◽  
Teresa Tórtola ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Immigrant Population ◽  
High Rate ◽  
Pleural Tuberculosis ◽  
Low Incidence

scholarly journals Correlation Between Pleural Fluid GenXpert® and Histopathology Finding of Pleural Biopsy in Tuberculous Pleural Effusion

2020 ◽  
Vol 38 (1) ◽  
pp. 1-6
Author(s):  
Sheilla Matheos ◽  
Isnin Anang Marhana ◽  
Anny Setijo Rahaju
Keyword(s):  
Pleural Effusion ◽  
Pleural Fluid ◽  
Standard Procedure ◽  
Nucleic Acid Amplification ◽  
Histopathological Analysis ◽  
Pleural Biopsy ◽  
Chi Square ◽  
Cross Sectional ◽  
Histopathological Findings ◽  
Pleural Tuberculosis

Backgrounds: Tuberculosis pleural effusion is the most common extrapulmonary TB after lymphadenitis TB, but a definite diagnosis is still a challenge. Pleural biopsy has historically been the gold standard procedure for the diagnosis of pleural tuberculosis. GenXpert® is a computerize test based in nucleic acid amplification tahat automatically detect MTB and rifampicin resistance. This study aimed to prove the correlation between pleural fluid GenXpert® and histopathological findings of pleural biopsy in patients with pleural tuberculosis. Methods: This study used an observational analytic design with a cross-sectional design conducted in Dr. Soetomo Hospital, Surabaya in March-June 2017. Statistic analysis was using chi square test and contingensi coofisient. The pleural GenXpert® was tested in 23 patients with pleural effusion and their biopsy speciments underwent histopathological analysis. Results: Histopathological findings of pleural biopsy was positive in 4 subjects and pleural fluid GenXpert® resulted positive in 6 subjects. There was significant correlation between pleural fluid GenXpert® and histopathological findings of specimen pleural biopsy in patients with pleural tuberculosis (P=0.040) with moderate strenght (P=0.014). Sensitivity and specificity of pleural fluid GenXpert® were 75.0% dan 84.2% respectively. Conclusions: There was significant correlation between pleural fluid GenXpert® and histopathological findings of pleural biopsy in patients with pleural tuberculosis. (J Respir Indo 2018; 38(1): 1-6)

scholarly journals Endobronchial tuberculosis: histopathological subsets and microbiological results

2012 ◽  
Vol 7 ◽  
Author(s):  
Sevket Ozkaya ◽  
Salih Bilgin ◽  
Serhat Findik ◽  
Hayriye Çete Kök ◽  
Canan Yuksel ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Lavage Fluid ◽  
Tracheobronchial Tree ◽  
Sputum Smear ◽  
Tuberculous Infection ◽  
Bronchial Lavage ◽  
Culture Positivity ◽  
Endobronchial Tuberculosis ◽  
Smear Negative ◽  
Histopathological Evidence

Background: Endobronchial tuberculosis (EBTB) is defined as a tuberculous infection of the tracheobronchial tree with microbial and histopathological evidence, with or without parenchymal involvement. Bronchoscopic appearances of EBTB have been divided into seven subtypes: actively caseating, edematous-hyperemic, fibrostenotic, tumorous, granular, ulcerative, and nonspecific bronchitic. However, information for establishing a definite microbiological diagnosis in each of these categories is lacking. We aimed to present bronchoscopic appearances and percentages for the EBTB subtypes and to compare bronchoscopic appearances with microbiological positivity in bronchial lavage fluid. Methods: From 2003 to 2009, 23 biopsy-proven EBTB patients were enrolled in the study. Diagnosis of EBTB was histopathologically confirmed in all patients. Results: The commonest subtype was the edematous-hyperemic type (34.7%); other subtypes in order of occurrence were: tumorous (21.7%), granular (17.3%), actively caseating (17.3%), fibrostenotic (4.3%), and nonspecific bronchitic (4.3%). Although all patients were sputum-smear-negative for acid-fast bacilli (AFB), 26% of patients were smear-positive for AFB in the bronchial lavage fluid. The bronchial lavage fluid grew Mycobacterium tuberculosis in 39.1% of all patients. The bronchial lavage smear positivity for AFB in the bronchial lavage fluid was 75%, 25%, 20%, 12.5%, 0%, and 0% for the granular, actively caseating, tumorous, edematous-hyperemic, fibrostenotic, and nonspecific bronchitic subtypes of EBTB, respectively. Culture positivity for Mycobacterium tuberculosis in bronchial lavage fluid was 75%, 50%, 40%, 25%, 0%, and 0%, respectively. Conclusion: The commonest subtype of EBTB was the edematous-hyperemic subtype. The granular type had the highest smear positivity and culture positivity for Mycobacterium tuberculosis in bronchial lavage fluid. Bronchoscopy should be performed in all patients suspected to have EBTB.

scholarly journals Pleural pathology in HIV-infected patients: features of morphological diagnostics

Morphologia ◽  
2021 ◽  
Vol 15 (3) ◽  
pp. 109-118
Author(s):  
I.V. Liskina ◽  
L.M. Zagaba
Keyword(s):  
Hiv Infection ◽  
Clinical Diagnosis ◽  
Molecular Genetic ◽  
Unknown Etiology ◽  
Pleural Effusions ◽  
Cd4 Cells ◽  
Morphological Examination ◽  
Genetic Studies ◽  
Pleural Tuberculosis ◽  
Morphological Diagnostics

Background. The progression of HIV infection is accompanied by the development of opportunistic diseases, including pleural effusions of various origins. Morphological examination of pleura tissue in cases of pleural effusion serves as the basis for establishing the etiology of the pathological process and, therefore, the final clinical diagnosis. Objective – analysis of results of morphological diagnostics of pleura lesions in HIV-infected patients in comparison with other laboratory tests and clinical diagnosis. Methods. 103 cases of pleurisy of various origins were studied. Pleural biopsies were obtained by various types of minimally invasive diagnostic interventions with subsequent morphological examination. Results were compared with the available data of microbiological and molecular genetic studies of pleural biopsies. Results. At the time of hospitalization the preliminary clinical diagnosis was pleurisy of unknown etiology in 96,1 % of cases. A combined disease was diagnosed – hepatitis C in a third of all observations according to the results of laboratory tests. Due to routine staining with hematoxylin and eosin, tuberculosis lesions of the pleura were diagnosed in 59,2 %, the second most frequent was the diagnosis of nonspecific pleurisy, 20,4 %. According to the duration of the process, acute pleural tuberculosis was established in 19,7 % of cases, the subacute form of tuberculosis pleurisy – in 54,1 % of cases, and chronic pleural tuberculosis was established in 22,9 % of cases. In 17,5 % of cases, in order to clarify the etiology of pleurisy, additional histochemical staining for infectious agents was performed. The results of microbiological and molecular genetic studies were established in 76,7 % of cases. The greatest number of M. tuberculosis detection was obtained during the culture study of the biopsy material and exudates. When comparing the final clinical diagnosis and the level of CD4 cells in peripheral blood, it was found that in most cases (74,5 %) pleural effusions developed at low counts of CD4 cells, less than 350/l. Conclusion. Tuberculosis predominates in the etiological structure of pleural effusions in patients with HIV infection. Pleural tuberculosis can be the main secondary disease or be combined with pulmonary tuberculosis. In second place in terms of frequency of occurrence, nonspecific pleurisy was diagnosed as a complication of the main secondary disease. Pleural effusions develop when CD4 cell counts are low. Morphological diagnostics of pleural lesions is the main research method in the diagnostic algorithm of cases of pleural effusions of unknown etiology against the background of HIV infection.

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