scholarly journals Emulgel based topical delivery system for loratadine

ADMET & DMPK ◽  
2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Vijay Kumar ◽  
Sheefali Mahant ◽  
Sheefali Mahant ◽  
Rekha Rao ◽  
Sanju Nanda
Keyword(s):  
Delivery System ◽  
Topical Delivery

Microsponges: An Overview

2017 ◽  
Vol 4 (4) ◽  
Author(s):  
Hamid Hussain ◽  
Divya Juyal ◽  
Archana Dhyani
Keyword(s):  
Controlled Release ◽  
Delivery System ◽  
Oral Delivery ◽  
Active Agent ◽  
Topical Delivery ◽  
Water Soluble ◽  
Wide Range ◽  
Porous Beads

Microsponge and Nanosponge delivery System was originally developed for topical delivery of drugs can also be used for controlled oral delivery of drugs using water soluble and bioerodible polymers. Microsponge delivery system (MDS) can entrap wide range of drugs and then release them onto the skin over a time by difussion mechanism to the skin. It is a unique technology for the controlled release of topical agents and consists of nano or micro porous beads loaded with active agent and also use for oral delivery of drugs using bioerodible polymers.

scholarly journals Topical Delivery System of Ophthalmic Drugs by Periocular Injection with Viscous Solution.

1999 ◽  
Vol 22 (9) ◽  
pp. 961-965 ◽  
Author(s):  
Hitoshi SASAKI ◽  
Satsuki KASHIWAGI ◽  
Takahiro MUKAI ◽  
Koyo NISHIDA ◽  
Junzo NAKAMURA ◽  
...  
Keyword(s):  
Delivery System ◽  
Topical Delivery ◽  
Ophthalmic Drugs ◽  
Viscous Solution

Voriconazole loaded nanostructured lipid carriers based topical delivery system: QbD based designing, characterization, in-vitro and ex-vivo evaluation

2019 ◽  
Vol 52 ◽  
pp. 303-315 ◽  
Author(s):  
Tejashree Waghule ◽  
Vamshi Krishna Rapalli ◽  
Gautam Singhvi ◽  
Prachi Manchanda ◽  
Neha Hans ◽  
...  
Keyword(s):  
Delivery System ◽  
Ex Vivo ◽  
Topical Delivery ◽  
Nanostructured Lipid Carriers

Characterization of Topical Delivery System of ZnPcSO^4to Use in Photodynamic Therapy of Skin Cancer

2010 ◽  
Author(s):  
Wanessa Medina ◽  
Clayton Azevedo ◽  
Patricia Farias ◽  
Beate Santos ◽  
Adriana Fontes ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Skin Cancer ◽  
Delivery System ◽  
Topical Delivery

scholarly journals Vesicular carriers containing phenylethyl resorcinol for topical delivery system; liposomes, transfersomes and invasomes

2018 ◽  
Vol 13 (5) ◽  
pp. 472-484 ◽  
Author(s):  
Thanaporn Amnuaikit ◽  
Tunyaluk Limsuwan ◽  
Pasarat Khongkow ◽  
Prapaporn Boonme
Keyword(s):  
Delivery System ◽  
Topical Delivery ◽  
Vesicular Carriers

scholarly journals Nanoemulgel for Improved Topical Delivery of Retinyl Palmitate: Formulation Design and Stability Evaluation

Nanomaterials ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 848 ◽  
Author(s):  
Mohammed S. Algahtani ◽  
Mohammad Zaki Ahmad ◽  
Javed Ahmad
Keyword(s):  
Droplet Size ◽  
Delivery System ◽  
Skin Irritation ◽  
Topical Delivery ◽  
Skin Aging ◽  
Retinyl Palmitate ◽  
Skin Permeability ◽  
Therapeutic Benefits ◽  
Behavior Study ◽  
Hydrogel System

Retinyl palmitate is a vitamin A ester belonging to the family of endogenous natural retinoid and used to treat various skin disorders like acne, skin aging, wrinkles, and dark spots, as well as to protect against psoriasis. Despite the known therapeutic benefits of retinyl palmitate, the conventional topical delivery of retinyl palmitate commonly associated with adverse reactions such as skin irritation, redness, excessive peeling, and dryness. Therefore, the current study aims to encapsulate the retinyl palmitate in nanoemulsion then incorporate it into a hydrogel system to improve the topical delivery and stability. Low-energy emulsification method was used for the nano-encapsulation of retinyl palmitate. The phase behavior study was used for the investigation and the optimization of the formulation. The droplet size of the optimized nanoemulsion was in nano dimension (16.71 nm) with low polydispersity index (PdI) (0.015), negative zeta potential (−20.6 mV). It demonstrated the influence of vortexing on droplet size and PdI during nanoemulsion preparation. The retinyl palmitate loaded nanoemulgel delivery system exhibited significant improvement (p < 0.05) in skin permeability after topical application. Employment of the nano-encapsulation approach afterward dispersion into hydrogel system for the development of a topical delivery system of retinyl palmitate resulted in improvement in its UV and storage stability as well.

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