scholarly journals Development of tuberculosis infection control guidelines in a pediatric HIV clinic in sub-Saharan Africa

2015 ◽  
Vol 5 (1) ◽  
pp. 2-5 ◽  
Author(s):  
J. G. Carlucci ◽  
L. Jin ◽  
J. E. Sanders ◽  
E. Q. Mohapi ◽  
A. M. Mandalakas
Keyword(s):  
Infection Control ◽  
Pediatric Hiv ◽  
Sub Saharan Africa ◽  
Tuberculosis Infection ◽  
Tuberculosis Infection Control ◽  
Sub Saharan ◽  
Infection Control Guidelines

Adherence to tuberculosis infection control guidelines by nurses in Lesotho

2015 ◽  
Vol 43 (7) ◽  
pp. 735-738 ◽  
Author(s):  
Eltony Mugomeri ◽  
Peter Chatanga ◽  
Mamotlatsi Lefunyane ◽  
Vurayai Ruhanya ◽  
George Nyandoro ◽  
...  
Keyword(s):  
Infection Control ◽  
Tuberculosis Infection ◽  
Tuberculosis Infection Control ◽  
Infection Control Guidelines

scholarly journals Addressing Pediatric HIV Pretreatment Drug Resistance and Virologic Failure in Sub-Saharan Africa: A Cost-Effectiveness Analysis of Diagnostic-Based Strategies in Children ≥3 Years Old

Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 567
Author(s):  
Mutita Siriruchatanon ◽  
Shan Liu ◽  
James G. Carlucci ◽  
Eva A. Enns ◽  
Horacio A. Duarte
Keyword(s):  
Drug Resistance ◽  
Cost Effectiveness ◽  
Virologic Failure ◽  
Pediatric Hiv ◽  
Sub Saharan Africa ◽  
Financial Investment ◽  
Switching Strategy ◽  
Wide Range ◽  
Sub Saharan ◽  
Living With Hiv

Improvement of antiretroviral therapy (ART) regimen switching practices and implementation of pretreatment drug resistance (PDR) testing are two potential approaches to improve health outcomes for children living with HIV. We developed a microsimulation model of disease progression and treatment focused on children with perinatally acquired HIV in sub-Saharan Africa who initiate ART at 3 years of age. We evaluated the cost-effectiveness of diagnostic-based strategies (improved switching and PDR testing), over a 10-year time horizon, in settings without and with pediatric dolutegravir (DTG) availability as first-line ART. The improved switching strategy increases the probability of switching to second-line ART when virologic failure is diagnosed through viral load testing. The PDR testing strategy involves a one-time PDR test prior to ART initiation to guide choice of initial regimen. When DTG is not available, PDR testing is dominated by the improved switching strategy, which has an incremental cost-effectiveness ratio (ICER) of USD 579/life-year gained (LY), relative to the status quo. If DTG is available, improved switching has a similar ICER (USD 591/LY) relative to the DTGstatus quo. Even when substantial financial investment is needed to achieve improved regimen switching practices, the improved switching strategy still has the potential to be cost-effective in a wide range of sub-Saharan African countries. Our analysis highlights the importance of strengthening existing laboratory monitoring systems to improve the health of children living with HIV.

scholarly journals Health care workers' recommendations for strengthening tuberculosis infection control in the Dominican Republic

2018 ◽  
Vol 42 ◽  
pp. 1-9
Author(s):  
Helena J. Chapman ◽  
Bienvenido A. Veras-Estévez ◽  
Jamie L. Pomeranz ◽  
Eddy N. Pérez-Then ◽  
Belkys Marcelino ◽  
...  
Keyword(s):  
Health Care ◽  
Dominican Republic ◽  
Infection Control ◽  
Health Care Workers ◽  
Tuberculosis Infection ◽  
Care Workers ◽  
Tuberculosis Infection Control
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