scholarly journals Drug-resistant tuberculosis in Eastern Europe: challenges and ways forward

2014 ◽  
Vol 4 (2) ◽  
pp. 3-12 ◽  
Author(s):  
C. D. Acosta ◽  
A. Dadu ◽  
A. Ramsay ◽  
M. Dara
Keyword(s):  
Eastern Europe ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis

Drug resistant tuberculosis soars in eastern Europe

BMJ ◽  
2004 ◽  
Vol 328 (Suppl S4) ◽  
pp. 0404137a
Author(s):  
Chibuzo Odigwe
Keyword(s):  
Eastern Europe ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis

Multi-drug-resistant tuberculosis in HIV positive patients in Eastern Europe

2014 ◽  
Vol 68 (3) ◽  
pp. 259-263 ◽  
Author(s):  
Frank A. Post ◽  
Daniel Grint ◽  
Anne Marie Werlinrud ◽  
Alexander Panteleev ◽  
Vieja Riekstina ◽  
...  
Keyword(s):  
Eastern Europe ◽  
Hiv Positive ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Multi Drug Resistant Tuberculosis

Characteristics of drug-resistant tuberculosis in Abkhazia (Georgia), a high-prevalence area in Eastern Europe

Tuberculosis ◽  
2009 ◽  
Vol 89 (4) ◽  
pp. 317-324 ◽  
Author(s):  
Manuela Pardini ◽  
Stefan Niemann ◽  
Francis Varaine ◽  
Elisabetta Iona ◽  
Francesca Meacci ◽  
...  
Keyword(s):  
Eastern Europe ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
High Prevalence

scholarly journals Factors contributing to drug-resistant tuberculosis treatment outcome in five countries in the Eastern Europe and Central Asia region

2020 ◽  
Vol 90 (1) ◽  
Author(s):  
Christian Auer ◽  
Rais Mazitov ◽  
Alisher Makhmudov ◽  
Bobojon Pirmahmadzoda ◽  
Alena Skrahina ◽  
...  
Keyword(s):  
Treatment Outcome ◽  
Eastern Europe ◽  
Central Asia ◽  
Oral Treatment ◽  
Primary Health Care System ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis ◽  
Clinical Records ◽  
Desk Review

Drug-resistant tuberculosis (DR-TB) is a global challenge and a major contributor of death from anti-microbial resistance. With the main aim to determine factors contributing to treatment outcomes observed among DR-TB patients in the countries in Eastern Europe and Central Asia (EECA), a multi-method study was conducted in: Azerbaijan, Belarus, Romania, Tajikistan and Ukraine. Both quantitative and qualitative methodologies were used for data collection and analysis. The quantitative approaches included a desk review of documents related to the DR-TB responses and an analysis of clinical records of DR-TB patients in selected health facilities of the five countries. Qualitative methods included in-depth interviews with national TB programme (NTP) managers, other healthcare providers and non-governmental organizations (NGOs) workers, as well as interviews and Focus Group Discussions (FGDs) with DR-TB patients. The desk review of 38 reports identified as the main challenges to address DR-TB financial and/or management issues and adverse events of the medicines. The most common recommendations related to treatment outcome focussed on general programme management, treatment regimen composition, clinical management and social support for the patients. In all the five countries the NTPs still have a vertical structure. Some integration into the primary health care system (PHC) already exists but further involvement of PHC facilities is feasible and recommended. Interviews with stakeholders indicated that alcoholism and homelessness and a lack of appropriate response to these issues remain as major challenges for a sub-set of patients. Civil society groups, NGOs and communities are substantially engaged in providing different services to DR-TB patients, especially in Ukraine, Romania and Tajikistan. Data from clinical records of 212 patients revealed that independent risk factors for unfavourable treatment outcome (death, loss to follow-up, failure) were culture-positivity at two months of treatment, history of treatment with second-line drugs and homelessness. More powerful, less toxic and shorter oral treatment regimens as well as comprehensive patient support are needed to improve treatment outcome of patients with DR-TB.

scholarly journals Fighting drug-resistant tuberculosis in eastern Europe

2017 ◽  
Vol 17 (7) ◽  
pp. 691-692
Author(s):  
Francis Drobniewski ◽  
Soudeh Ehsani ◽  
Masoud Dara
Keyword(s):  
Eastern Europe ◽  
Drug Resistant ◽  
Drug Resistant Tuberculosis ◽  
Resistant Tuberculosis
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