scholarly journals Immunomodulating and anticancer properties of fungi

2013 ◽  
Vol 47 (1) ◽  
pp. 91-96 ◽  
Author(s):  
Kazimierz Kopczyński
Keyword(s):  
Cardiovascular Disease ◽  
Vitamin D ◽  
Immune System ◽  
Human Health ◽  
Cholesterol Level ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Anticancer Properties ◽  
Active Substances

Fungi contain a number of biologically active substances whose importance for human health has been confirmed in several studies. In particular, β-glucans, selenium, vitamin D, C and E should be mentioned. These substances play an important role in shaping the immune system and prevent cancer. β-Glucans reduce the risk of cardiovascular disease and lower the cholesterol level.

scholarly journals Biotechnological research in Ukraine for solving energy, medical-biological and medical-ecological problems in 2009-2015 taking into account the implementation of the association agreement with the EU

2018 ◽  
pp. 49-71 ◽  
Author(s):  
Igor Yu. Matyushenko ◽  
Iryna An. Sviatukha ◽  
Marina S. Loktionova
Keyword(s):  
Human Health ◽  
New Technologies ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
National Academy Of Sciences ◽  
Animal Cells ◽  
Association Agreement ◽  
Modern Methods ◽  
Ecological Problems ◽  
Active Substances

This article summarizes the main results of the biotechnological research of the National Academy of Sciences of Ukraine aimed at solving energy, medical-biological and medical-ecological problems during the period from 2009 to 2015. The prospective bioresources and directions of implementation of the latest technologies of bioenergy conversion for the production of liquid biofuels and expansion of their use for biodiesel were determined. The latest medical and biological and bioengineering technologies for human health and the national economy, biologically active substances for human health, ecological and economic mechanisms of rational use, protection and monitoring of natural resources, new technologies for the efficient use of energy resources were presented in the article. The authors systematized the results of the current research of the National Academy of Science of Ukraine aimed at the development of modern methods for the prevention and diagnosis of diseases in humans and animals, modern methods of cell biotechnology and metabolic engineering for the creation of superproducts of biologically active substances, new forms of plants and microorganisms, the genetic design of improved microorganisms and lines of plant and animal cells for the development of medical and agricultural biotechnology. The authors proved that these directions of research fully correspond to the world-wide trends in research in biomedicine.

scholarly journals What Function Do Platelets Play in Inflammation and Bacterial and Viral Infections?

2021 ◽  
Vol 12 ◽  
Author(s):  
Beata Tokarz-Deptuła ◽  
Joanna Palma ◽  
Łukasz Baraniecki ◽  
Michał Stosik ◽  
Roman Kołacz ◽  
...  
Keyword(s):  
Immune System ◽  
Extracellular Vesicles ◽  
Vascular Endothelium ◽  
Viral Infections ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Active Substances

The article presents the function of platelets in inflammation as well as in bacterial and viral infections, which are the result of their reaction with the endovascular environment, including cells of damaged vascular endothelium and cells of the immune system. This role of platelets is conditioned by biologically active substances present in their granules and in their specific structures – EV (extracellular vesicles).

Microscopic fungi of lithobiont communities of Argentine Islands Region: Data from the 22nd Ukrainian Antarctic Expedition

2020 ◽  
Vol 62 (1-2) ◽  
pp. 49-68
Author(s):  
T. O. Kondratiuk ◽  
T. V. Beregova ◽  
I. Yu. Parnikoza ◽  
S. Y. Kondratyuk ◽  
A. Thell
Keyword(s):  
Filamentous Fungi ◽  
Mucor Circinelloides ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Microscopic Fungi ◽  
Rhodotorula Rubra ◽  
Yeast Fungi ◽  
Antarctic Expedition ◽  
Geomyces Pannorum ◽  
Active Substances

The identification of the diversity of microscopic fungi of lithobiont communities of the Argentine Islands in specimens collected during the 22nd Ukrainian Antarctic Expedition was the purpose of this work. Samples of rock, soil, mosses and lichens of rock micro-habitats of “Crustose lichen sub-formation and fruticose lichen and moss cushion sub-formation” were used in the work. These samples were used for extracting and cultivation of filamentous fungi on dense nutrient media. Determination of physiological and biochemical characteristics and identification of yeast-like fungi were performed using a microbiological analyser ‘Vitek-2’ (‘Bio Merieux’, France). Cultivation of microorganisms was carried out at temperatures from +2 to +37 °C. In results cultures of microscopic fungi of Zygomycota (Mucor circinelloides), Ascomycota (species of the genera cf. Tlielebolus, Talaromyces), representatives of the Anamorphic fungi group (Geomyces pannorum, species of the genera Alternaria, Acremonium, Aspergillus, Penicillium, and Cladosporium) were isolated from Antarctic samples. Microscopic fungi Penicillium spp. were dominated after the frequency in the studied samples (54.5%). Rhodotorula rubra and Candida sp. among isolated yeast fungi, and dark pigmented fungi represented by Aureobasidium pulhdans and Exophiala spp. were identified. The biological properties of a number of isolated fungi (the potential ability to synthesise important biologically active substances: melanins, carotenoids, lipids) are characterised. Mycobiota of rock communities of Argentine Islands is rich on filamentous and yeast fungi similarly to other regions of Antarctica. A number of fungi investigated are potentially able to synthesise biologically active substances. The dark pigmented species of the genera Cladosporium, Exophiala, Aureobasidium pulhdans, capable of melanin synthesis; ‘red’ yeast Rhodotorula rubra (carotenoid producers and resistant to toxic metals); Mucor circinelloides and Geomyces pannorum, lipid producers, are among these fungi. Yeast-like fungi assimilated a wide range of carbohydrates, which will allow them to be further used for cultivation in laboratory and process conditions. The collection of technologically promising strains of microorganisms, part of the Culture Collection of Fungi at Taras Shevchenko National University of Kyiv (Ukraine), is updated with isolated species (strains) of filamentous fungi and yeast – potential producers of biologically active substances, obtained within this study.

The content of decenoic acids in drone brood preparations and combined preparations based on it

Biomics ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 389-393
Author(s):  
D.V. Mitrofanov ◽  
N.V. Budnikova
Keyword(s):  
Royal Jelly ◽  
Storage Conditions ◽  
Water Soluble ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Strict Adherence ◽  
Drone Brood ◽  
Wide Range ◽  
Active Substances ◽  
Melanin Complex

The drone brood contains a large number of substances with antioxidant activity. These substances require stabilization and strict adherence to storage conditions. Among these substances are unique decenoic acids, the content of which is an indicator of the quality of drone brood and products based on it. The ability of drone brood to reduce the manifestations of oxidative stress is shown. There are dietary supplements for food and drugs based on drone brood, which are used for a wide range of diseases. Together with drone brood, chitosan-containing products, propolis, royal jelly can be used. They enrich the composition with their own biologically active substances and affect the preservation of the biologically active substances of the drone brood. Promising are the products containing, in addition to the drone brood, a chitin-chitosan-melanin complex from bees, propolis, royal jelly. The chitin-chitosan-melanin complex in the amount of 5% in the composition of the adsorbent practically does not affect the preservation of decenic acids, while in the amount of 2% and 10% it somewhat worsens. The acid-soluble and water-soluble chitosan of marine crustaceans significantly worsens the preservation of decenoic acids in the product. Drone brood with royal jelly demonstrates a rather high content of decenoic acids. When propolis is introduced into the composition of the product, the content of decenoic acids increases according to the content of propolis.

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