scholarly journals Optical coherence tomography for precision brain imaging, neurosurgical guidance and minimally invasive theranostics

2018 ◽  
Vol 12 (1) ◽  
pp. 12-23 ◽  
Author(s):  
Yingwei Fan ◽  
Yan Xia ◽  
Xinran Zhang ◽  
Yu Sun ◽  
Jie Tang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Minimally Invasive ◽  
Brain Imaging ◽  
Optical Coherence

scholarly journals Full‐field swept‐source optical coherence tomography and neural tissue classification for deep brain imaging

2019 ◽  
Vol 13 (2) ◽  
Author(s):  
Ilan Felts Almog ◽  
Fu‐Der Chen ◽  
Suhan Senova ◽  
Anton Fomenko ◽  
Elise Gondard ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Brain Imaging ◽  
Neural Tissue ◽  
Optical Coherence ◽  
Tissue Classification ◽  
Swept Source ◽  
Full Field ◽  
Deep Brain

scholarly journals A Mesh-Based Monte Carlo Study for Investigating Structural and Functional Imaging of Brain Tissue Using Optical Coherence Tomography

2019 ◽  
Vol 9 (19) ◽  
pp. 4008
Author(s):  
Luying Yi ◽  
Liqun Sun ◽  
Mingli Zou ◽  
Bo Hou
Keyword(s):  
Optical Coherence Tomography ◽  
Monte Carlo ◽  
Brain Imaging ◽  
Brain Tissue ◽  
Three Dimensional ◽  
Hemoglobin Concentration ◽  
Monte Carlo Study ◽  
Biological Tissues ◽  
Optical Coherence ◽  
Quantitative Accuracy

Optical coherence tomography (OCT) can obtain high-resolution three-dimensional (3D) structural images of biological tissues, and spectroscopic OCT, which is one of the functional extensions of OCT, can also quantify chromophores of tissues. Due to its unique features, OCT has been increasingly used for brain imaging. To support the development of the simulation and analysis tools on which OCT-based brain imaging depends, a model of mesh-based Monte Carlo for OCT (MMC-OCT) is presented in this work to study OCT signals reflecting the structural and functional activities of brain tissue. In addition, an approach to improve the quantitative accuracy of chromophores in tissue is proposed and validated by MMC-OCT simulations. Specifically, the OCT-based brain structural imaging was first simulated to illustrate and validate the MMC-OCT strategy. We then focused on the influences of different wavelengths on the measurement of hemoglobin concentration C, oxygen saturation Y, and scattering coefficient S in brain tissue. Finally, it is proposed and verified here that the measurement accuracy of C, Y, and S can be improved by selecting appropriate wavelengths for calculation, which contributes to the experimental study of brain functional sensing.

scholarly journals En-face optical coherence tomography/fluorescence endomicroscopy for minimally invasive imaging using a robotic scanner

2019 ◽  
Vol 24 (06) ◽  
pp. 1 ◽  
Author(s):  
Manuel J. Marques ◽  
Michael R. Hughes ◽  
Khushi Vyas ◽  
Andrew Thrapp ◽  
Haojie Zhang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Minimally Invasive ◽  
Optical Coherence ◽  
En Face

scholarly journals Longitudinal deep-brain imaging in mouse using visible-light optical coherence tomography through chronic microprism cranial window

2019 ◽  
Vol 10 (10) ◽  
pp. 5235 ◽  
Author(s):  
Lisa Beckmann ◽  
Xian Zhang ◽  
Neil A. Nadkarni ◽  
Zhen Cai ◽  
Ayush Batra ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visible Light ◽  
Brain Imaging ◽  
Optical Coherence ◽  
Cranial Window ◽  
Deep Brain
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