Use Of Nano Particles And Nanocrystals In Drug Discovery

10.5580/f3a ◽  
2009 ◽  
Vol 3 (1) ◽  
Keyword(s):  
Drug Discovery ◽  
Nano Particles

scholarly journals Synthesis of Silver Nano-Particles from Natural Products and its Applications

2019 ◽  
Vol 18 (2) ◽  
pp. 37-44
Author(s):  
Anjali Sharma ◽  
Sherin Thomas ◽  
Agnes Mary Mathew ◽  
Anil Kumar Agarwal
Keyword(s):  
Silver Nanoparticles ◽  
Natural Products ◽  
Drug Discovery ◽  
Nano Particles ◽  
Multiple Drug ◽  
Drug Resistant ◽  
Multiple Drug Resistant

Infections, that are resistant to the various antibiotics, have increased and become a major concern in the field of drug discovery. This has initiated the need to improve the quality of the existing drugs or find an innovative set of strategies to overcome this issue. In the hope of treating multiple-drug resistant infections, the concept of using natural products to form nanoparticles that could resolve the problem has been introduced. This review talks about the myriad ways of synthesis of silver nanoparticles from natural products which helps in the treatment of multiple diseases.

Electron holography of catalysts

1995 ◽  
Vol 53 ◽  
pp. 416-417
Author(s):  
A. K. Datye ◽  
D. S. Kalakkad ◽  
L. F. Allard ◽  
E. Völkl
Keyword(s):  
Heterogeneous Catalysts ◽  
High Surface ◽  
High Surface Area ◽  
Atomic Scale ◽  
Nano Particles ◽  
Phase Image ◽  
Electron Holography ◽  
Specimen Thickness ◽  
Phase Information ◽  
Particle Structure

The active phase in heterogeneous catalysts consists of nanometer-sized metal or oxide particles dispersed within the tortuous pore structure of a high surface area matrix. Such catalysts are extensively used for controlling emissions from automobile exhausts or in industrial processes such as the refining of crude oil to produce gasoline. The morphology of these nano-particles is of great interest to catalytic chemists since it affects the activity and selectivity for a class of reactions known as structure-sensitive reactions. In this paper, we describe some of the challenges in the study of heterogeneous catalysts, and provide examples of how electron holography can help in extracting details of particle structure and morphology on an atomic scale.Conventional high-resolution TEM imaging methods permit the image intensity to be recorded, but the phase information in the complex image wave is lost. However, it is the phase information which is sensitive at the atomic scale to changes in specimen thickness and composition, and thus analysis of the phase image can yield important information on morphological details at the nanometer level.

Coherent electron nanodiffraction from clean silver nano particles in a UHV STEM

1993 ◽  
Vol 51 ◽  
pp. 1058-1059
Author(s):  
J. Liu ◽  
M. Pan ◽  
G. E. Spinnler
Keyword(s):  
Supported Catalysts ◽  
Imaging Techniques ◽  
Nano Particles ◽  
Metal Particles ◽  
Shape Structure ◽  
Dynamical Simulations ◽  
Small Metal Particles ◽  
Extract Information

Small metal particles have peculiar chemical and physical properties as compared to bulk materials. They are especially important in catalysis since metal particles are common constituents of supported catalysts. The structural characterization of small particles is of primary importance for the understanding of structure-catalytic activity relationships. The shape and size of metal particles larger than approximately 5 nm in diameter can be determined by several imaging techniques. It is difficult, however, to deduce the shape of smaller metal particles. Coherent electron nanodiffraction (CEND) patterns from nano particles contain information about the particle size, shape, structure and defects etc. As part of an on-going program of STEM characterization of supported catalysts we report some preliminary results of CEND study of Ag nano particles, deposited in situ in a UHV STEM instrument, and compare the experimental results with full dynamical simulations in order to extract information about the shape of Ag nano particles.

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