Rare Case Of Plasma Cell Hyperplasia (Inflammatory Pseudotumor) Of The Central Nervous System

10.5580/79a ◽  
2010 ◽  
Vol 11 (2) ◽  
Neurosurgery ◽  
1989 ◽  
Vol 24 (3) ◽  
pp. 429-434 ◽  
Author(s):  
Karen M. Weidenheim ◽  
Wallace G. Campbell ◽  
H. Warren Goldman

Abstract Hematopoietic proliferations rich in plasma cells rarely occur within the central nervous system without the involvement of other organ systems. Depending on their histological pattern and cellular composition, several different terms, including plasmacytoma, plasma cell granuloma, hyalinizing plasmacytic granulomatosis, and inflammatory meningioma, are used for these lesions. We report a left temporal dural lesion composed of plasma cells, lymphocytes, histiocytes, and rare eosinophils with hyaline changes and a suggestion of follicle formation, which stained predominantly for IgG and kappa light chains. This lesion arose in an otherwise healthy 52-year-old woman. Free kappa light chains without a monoclonal peak were found in the urine. We are aware of only two other heterogeneous, predominantly plasmacytic, solitary dural lesions that were found to be monoclonal on immunohistochemical examination. The label atypical monoclonal plasma cell hyperplasia appears to suit the morphological characteristics of our lesion. We suggest that a spectrum of solitary plasmacytic lesions may occur within the central nervous system and that atypical plasma cell hyperplasias have the potential to evolve into plasmacytoma. The preneoplastic nature of this lesion and its potential for evolution to malignant myeloma should be considered when planning treatment and lifelong follow-up for patients.


Neurosurgery ◽  
1989 ◽  
Vol 24 (3) ◽  
pp. 429???34 ◽  
Author(s):  
K M Weidenheim ◽  
W G Campbell ◽  
H W Goldman

2021 ◽  
Vol 21 ◽  
pp. S437-S438
Author(s):  
Carine Ribeiro Franzon ◽  
Andressa Oliveira Martin Wagner ◽  
Annelise Correa Wengerkievicz Lopes ◽  
Douglas Gebauer Bona ◽  
Talita Bertazzo Schmitz

2019 ◽  
Vol 59 (3) ◽  
pp. 135-139
Author(s):  
Takayuki Murase ◽  
Atsushi Inagaki ◽  
Ayako Masaki ◽  
Keiichiro Fujii ◽  
Tomoko Narita ◽  
...  

2013 ◽  
Vol 11 (2) ◽  
pp. 224-226 ◽  
Author(s):  
Carlos Eduardo Molinari Nardi ◽  
Alexandre Wakil Burzichelli ◽  
Elio Gilberto Pfuetzenreiter ◽  
Rogerio Aparecido Dedivitis

Schwannoma is a benign encapsulated tumor that originates from the Schwann cells lining nerve fibers outside the central nervous system. We report a rare case of schwannoma that arose from the left arythenoid cartilage The patient underwent excision of the mass through microlaryngeal endoscopic procedure. No recurrence was observed during follow-up.


Neurosurgery ◽  
1994 ◽  
Vol 35 (4) ◽  
pp. 744-747 ◽  
Author(s):  
John Hsiang ◽  
David Moorhouse ◽  
David Barba

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