A case for biopsying all adult adenoidal tissue

10.5580/653 ◽  
2009 ◽  
Vol 9 (2) ◽  
Keyword(s):  
Adenoidal Tissue

Effect of topical mometasone furoate on adenoidal lymphoid tissue: a light microscopic study

2019 ◽  
Vol 133 (2) ◽  
pp. 106-109 ◽  
Author(s):  
M R Ahmed ◽  
A S Abou-Halawa ◽  
I H Ibrahim ◽  
R F Zittoon ◽  
E F Y Makary
Keyword(s):  
Nasal Spray ◽  
Lymphoid Tissue ◽  
Topical Steroid ◽  
Upper Airway ◽  
Mometasone Furoate ◽  
Control Group ◽  
Adenoid Hypertrophy ◽  
Nasal Steroids ◽  
Grade 3 ◽  
Adenoidal Tissue

AbstractBackgroundAdenoid hypertrophy is a common cause of upper airway obstruction, and adenoidectomy is one of the most frequently performed operations in children. Topical nasal steroids can act directly on nasopharyngeal lymphoid tissue to decrease its reactive inflammatory changes and potentially reduce its size.ObjectiveTo study the light microscopic changes in adenoidal lymphoid tissue after one month of topical steroid use.MethodsTwenty-six children with adenoid hypertrophy grade 3 scheduled for adenoidectomy were randomly divided into two equal groups: one group received mometasone furoate aqueous nasal spray (Nasonex) 100 mcg/day for four weeks, and a control group received nasal normal saline 0.9 per cent for four weeks. The removed adenoids were examined histopathologically.ResultsAdenoidal tissue from the mometasone group had less reactive germinal centres and less spongiosis compared to the control group. The latter showed proliferating, reactive, variable sized and shaped lymphoid follicles, with congested blood vessels in the interfollicular areas.ConclusionThe use of intranasal mometasone furoate aqueous nasal spray (Nasonex) for one month reduced adenoidal tissue reactive cellular changes and its vascularity. This is, however, a pilot study; a longer treatment period is needed to assess the effect of treatment on adenoidal size.

Use of narrow-band imaging in detection of nasopharyngeal carcinoma

2013 ◽  
Vol 127 (2) ◽  
pp. 163-169 ◽  
Author(s):  
J F Thong ◽  
D Loke ◽  
R Karumathil Sivasankarannair ◽  
P Mok
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Papillary Adenocarcinoma ◽  
Nasopharyngeal Mass ◽  
Surface Patterns ◽  
Brown Centre ◽  
Epstein Barr ◽  
Characteristic Features ◽  
Adenoidal Tissue

AbstractAim:To compare narrow-band images of nasopharyngeal carcinoma with those of normal adenoidal tissue.Method:Patients with a nasopharyngeal mass were evaluated using both conventional white light and narrow-band light. Biopsies were performed and Epstein–Barr viral serology was tested for all patients.Results:Thirty consecutive patients were recruited. Twenty-one patients had normal adenoidal tissue and seven had nasopharyngeal carcinoma. One patient with papillary adenocarcinoma was excluded. The features of narrow-band imaging in normal adenoidal tissue were: (1) a regularly arranged follicular pattern, and (2) each ‘follicle’ comprising a pale centre with surrounding dark periphery. The features of narrow-band imaging in nasopharyngeal carcinoma were: (1) absence of surface patterns (n = 7), and/or (2) ‘reverse’, haphazard follicular pattern comprising a dark brown centre and pale periphery (n = 3).Conclusion:Narrow-band imaging of the surface of adenoidal tissue and nasopharyngeal carcinoma appears to identify distinct, characteristic features as described. Narrow-band imaging may be a useful adjunct in differentiating normal adenoidal tissue from malignancy. Further studies are needed to evaluate its diagnostic accuracy.

Adenoidal tissue mass as a clinical guide of disease evolution in vertically HIV-1 infected children

1999 ◽  
Vol 51 (3) ◽  
pp. 145-155 ◽  
Author(s):  
Margarita Bartolomé Benito ◽  
Teresa Hernández Sampelayo ◽  
Dolores Gurbindo ◽  
Silvia Sánchez-Ramón ◽  
Eugenio Molina Gómez ◽  
...  
Keyword(s):  
Tissue Mass ◽  
Disease Evolution ◽  
Adenoidal Tissue ◽  
Hiv 1

scholarly journals Adenoid hypertrophy existence in adulthood- a truth revealed

2014 ◽  
Vol 03 (01) ◽  
pp. 12-16
Author(s):  
Atul M Bage ◽  
Anand Karthikeyan D. ◽  
Nutan N Bage
Keyword(s):  
Nasal Obstruction ◽  
Strong Association ◽  
Endoscopic Examination ◽  
P Value ◽  
Adenoid Hypertrophy ◽  
Macroscopic Appearance ◽  
True Incidence ◽  
Presenting Symptoms ◽  
Waldeyer’S Ring ◽  
Adenoidal Tissue

Abstract Background and aims: The adenoids (nasopharyngeal tonsils) are part of Waldeyer’s ring of lymphoid tissue. Endoscopic examination of the nasopharynx increasingly recognized that adenoidal tissue in adults is not an uncommon finding. The aims of this study were to determine prevalence of adult adenoid tissue and the possible reasons behind it. Methods: A retrospective study of 1,100 adult patients, who had routine nasal endoscopic examination for nasal obstruction and related pathologies, was undertaken. 84 cases with incidental hypertrophied adenoid were reviewed to determine the probable cause, presenting symptoms, clinical suspicion and final histological diagnosis. Results: The age of patients ranged from 18 years to 77 years. Median age was 32 years. 59 (70.24%) of adenoid hypertrophy patients were smokers and only 25 (29.76%) were nonsmokers suggesting strong association between smoking and adult adenoid hypertrophy with odds ratio=5.3251, χ2value of 54.23 and an extremely significant p value. All the 84 cases were confirmed histopathologically as Reactive adenoid hyperplasia and no signs of malignancy in any of them. Conclusions: The true incidence of adenoidal hypertrophy in adults is unknown. Adenoidal tissue in adults, if present, must always be biopsied or removed irrespective of their macroscopic appearance. The result underlines the importance of considering adenoid hypertrophy as a cause or contributing factor in nasal obstruction and related pathologies in adults. It also supports the theory that it represents a long-standing inflammatory process rather than being a novel clinical entity.

scholarly journals 509 Nasal SCC in a Young Caucasian Male

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
A Calmuc
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Case Reports ◽  
Stage Iv ◽  
Caucasian Male ◽  
Clinical Notes ◽  
Progression Of Disease ◽  
Caucasian Patients ◽  
Adenoidal Tissue

Abstract Introduction Nasal squamous cell carcinoma (SCC) is common in Asian men in their 50s. However, 1 - 2 per million 15–19-year-old Caucasian patients will also develop nasal SCC. This case reports a rare finding of a 19-year-old Caucasian male with nasal SCC. Method Medical records were used to access to all relevant clinical notes for the patient, including blood results, clinical documentation, imaging, and histology. The patient’s clinical journey was reviewed from initial referral to the ENT department to diagnosis with non-keratinising squamous cell carcinoma (NKSCC) stage IV b. Progression of disease: The patient was initially referred to ENT with unilateral tinnitus and temporal headache and diagnosed in clinic with glue ear and hypertrophic adenoidal tissue. He was due to have grommets and EUA, which was postponed due to the COVID-19 pandemic and lack of clinical suspicion of SCC. Patient was later seen in ED for epistaxis, and then for neck swelling after which he was diagnosed with SCC. Conclusions As the patient is a young, caucasian and a non-smoker, the initial diagnosis was lymphoma rather than SCC. This highlights the difficulties of diagnosing this type of cancer in young Caucasian patients.

Mast cells in aural polyps: a preliminary report

1995 ◽  
Vol 109 (6) ◽  
pp. 491-494 ◽  
Author(s):  
S. S. M. Hussain ◽  
J. M. Hopkinson
Keyword(s):  
Electron Microscopy ◽  
Mast Cells ◽  
Preliminary Report ◽  
Nasal Polyps ◽  
Biologically Active ◽  
Upper Aerodigestive Tract ◽  
Inflammatory Conditions ◽  
Preliminary Study ◽  
One Year ◽  
Adenoidal Tissue

AbstractMast cells are a rich source of potent biologically active mediators and are found in connective tissue, associated with blood vessels in many varied inflammatory conditions. Mast cells have been described in nasal polyps and turbinates and in adenoidal tissue in the upper aerodigestive tract. As the middle ear lining is contiguous with the nose and the nasopharynx, the presence of mast cells in aural polyps is interesting.This preliminary study investigated the presence of mast cells in inflammatory aural polyps using light microscopy. All patients presenting to the department in one year were included. Patients with previous ear disease or surgery and in whom cholesteatoma was suspected were excluded. Except for one patient mast cells were seen in all aural polyps. The implications of these findings is discussed. Further work is needed using electron microscopy.

Relationship between bacteriology of the adenoid core and middle meatus in children with sinusitis

2010 ◽  
Vol 125 (3) ◽  
pp. 279-281 ◽  
Author(s):  
S Elwany ◽  
A N El-Dine ◽  
A El-Medany ◽  
A Omran ◽  
Z Mandour ◽  
...  
Keyword(s):  
Predictive Value ◽  
Bacterial Species ◽  
Group A Streptococci ◽  
Middle Meatus ◽  
University Hospitals ◽  
Coagulase Negative Staphylococci ◽  
Airway Patency ◽  
Group A ◽  
Adenoidal Tissue ◽  
Core Culture

AbstractObjective:To assess the correlation between bacterial pathogens in the adenoid core and the middle meatus, in children with hypertrophied adenoids and chronic or recurrent sinusitis.Design:The study was conducted at Alexandria University Hospitals. We included 103 children aged four to 12 years who were scheduled for adenoidectomy and who had clinical and/or radiological evidence of chronic or recurrent sinusitis. Adenoid core specimens and middle meatal swabs were obtained from every patient and were sent for bacteriological evaluation using standard qualitative and quantitative microbiological techniques. The results were statistically analysed.Results:The bacterial species isolated most frequently from the adenoid core were coagulase-negative staphylococci (40.8 per cent),Staphylococcus aureus(22.3 per cent),Streptococcus pneumoniae(18.4 per cent),Haemophilus influenzae(16.5 per cent) and group A streptococci (15.5 per cent). The bacterial species isolated most frequently from the middle meatus were coagulase-negative staphylococci (41.7 per cent),S aureus(32 per cent),S pneumoniae(28.1 per cent),H influenzae(21.6 per cent) and group A streptococci (19.4 per cent). The adenoid core and middle meatal cultures were both positive for at least one bacterial species in 63 cases, and were both negative in 25 cases. In six cases, a positive adenoid core culture was associated with a negative middle meatal culture. In five cases, a negative adenoid core culture was associated with a positive middle meatal culture (for one or more pathogenic species). Thus, adenoid core culture had a positive predictive value of 91.5 in forecasting the middle meatal culture result, and a negative predictive value of 84.3.Conclusion:Apart from its effect on nasal airway patency, adenoidal tissue may function as a bacterial reservoir initiating and maintaining sinus infection in children. These study findings support a potential role for adenoidectomy in the treatment of chronic or recurrent paediatric sinusitis.

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